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Human pathogens transmitted through environmental pathways are subject to stress and pressures outside of the host. These pressures may cause pathogen pathovars to diverge in their environmental persistence and their infectivity on an…

Populations and Evolution · Quantitative Biology 2018-02-16 Andrew F. Brouwer , Marisa C. Eisenberg , Nancy G. Love , Joseph N. S. Eisenberg

We introduce and analyze a within-host dynamical model of the coevolution between rapidly mutating pathogens and the adaptive immune response. Pathogen mutation and a homeostatic constraint on lymphocytes both play a role in allowing the…

Populations and Evolution · Quantitative Biology 2014-08-06 Kimberly J. Schlesinger , Sean P. Stromberg , Jean M. Carlson

The spread of infectious diseases, rumors, fashions, innovations are complex contagion processes, embedded both in networked and spatial contexts. Here we investigate the pattern dynamics of a complex contagion, where two agents, say $A$…

Physics and Society · Physics 2019-02-18 Li Chen

Epidemic processes are used commonly for modeling and analysis of biological networks, computer networks, and human contact networks. The idea of competing viruses has been explored recently, motivated by the spread of different ideas along…

Optimization and Control · Mathematics 2017-05-16 Philip E. Paré , Ji Liu , Carolyn L. Beck , Angelia Nedić , Tamer Başar

Habitat fragmentation, often driven by human activities, alters ecological landscapes by disrupting connectivity and reshaping species interactions. In such fragmented environments, habitats can be modeled as networks, where individuals…

Populations and Evolution · Quantitative Biology 2025-11-07 James Austin Orgeron , Malbor Asllani

We use a multitype continuous time Markov branching process model to describe the dynamics of the spread of parasites of two types that can mutate into each other in a common host population. Instead of using a single virulence…

Probability · Mathematics 2011-09-02 Konstantin Borovkov , Robert Day , Timothy Rice

We formulate a compartmental model for the propagation of a respiratory disease in a patchy environment. The patches are connected through the mobility of individuals, and we assume that disease transmission and recovery are possible during…

Populations and Evolution · Quantitative Biology 2021-10-11 Indrajit Ghosh , Sk Shahid Nadim , Soumyendu Raha , Debnath Pal

Coinfection phenomena are common in nature, yet there is a lack of analytical approaches for coinfection systems with a high number of circulating and interacting strains. In this paper, we investigated a coinfection SIS framework applied…

Populations and Evolution · Quantitative Biology 2026-02-06 Sten Madec , Nicola Cinardi , Erida Gjini

Despite being similar in structure, functioning, and size viral pathogens enjoy very different mostly well-defined ways of life. They occupy their hosts for a few days (influenza), for a few weeks (measles), or even lifelong (HCV), which…

Populations and Evolution · Quantitative Biology 2020-05-01 Alexander Lange

The sustainable use of multicomponent treatments such as combination therapies, combination vaccines/chemicals, and plants carrying multigenic resistance requires an understanding of how their population-wide deployment affects the speed of…

Populations and Evolution · Quantitative Biology 2015-06-16 Romain Bourget , Loïc Chaumont , Natalia Sapoukhina

Mutualists and pathogens, collectively called symbionts, are ubiquitous in plant communities. While some symbionts are highly host-specific, others associate with multiple hosts. The outcomes of multispecies host-symbiont interactions with…

Probability · Mathematics 2007-05-23 N. Lanchier , C. Neuhauser

Diseases spread through host populations over the networks of contacts between individuals, and a number of results about this process have been derived in recent years by exploiting connections between epidemic processes and bond…

Statistical Mechanics · Physics 2007-05-23 M. E. J. Newman

Movement behavior of biological entities plays a crucial role in their destiny through regulating their intraspecific and interspecific interactions as well as their interaction with surrounding environment. In spite of various models for…

Tissues and Organs · Quantitative Biology 2017-11-10 Youness Azimzade

We introduce a model called Host-Pathogen game for studying biological competitions. Notably, we focus on the invasive dynamics of external agents, like bacteria, within a host organism. The former are mapped to a population of defectors…

Populations and Evolution · Quantitative Biology 2018-09-03 Marco Alberto Javarone

Human diseases spread over networks of contacts between individuals and a substantial body of recent research has focused on the dynamics of the spreading process. Here we examine a model of two competing diseases spreading over the same…

Physics and Society · Physics 2015-03-19 Brian Karrer , M. E. J. Newman

The propagation of infectious diseases and its impact on individuals play a major role in disease dynamics, and it is important to incorporate population heterogeneity into efforts to study diseases. As a simplistic but illustrative…

Populations and Evolution · Quantitative Biology 2019-07-24 Juan G. Calvo , Alberto Hernández , Mason A. Porter , Fabio Sanchez

We investigate the spatial dynamics of two disease epidemics reaching a three-species cyclic model. Regardless of their species, all individuals are susceptible to being infected with two different pathogens, which spread through…

Populations and Evolution · Quantitative Biology 2024-06-05 J. Menezes , E. Rangel

Metapopulation models have been instrumental in demonstrating the ecological impact of landscape structure on the survival of a focal species in complex environments. However, extensions to multiple species with arbitrary dispersal networks…

Populations and Evolution · Quantitative Biology 2024-11-06 Prajwal Padmanabha , Giorgio Nicoletti , Davide Bernardi , Samir Suweis , Sandro Azaele , Andrea Rinaldo , Amos Maritan

Population structure induced by both spatial embedding and more general networks of interaction, such as model social networks, have been shown to have a fundamental effect on the dynamics and outcome of evolutionary games. These effects…

Populations and Evolution · Quantitative Biology 2009-11-13 Gergely J Szollosi , Imre Derenyi

Human mobility, contact patterns, and their interplay are key aspects of our social behavior that shape the spread of infectious diseases across different regions. In the light of new evidence and data sets about these two elements,…

Physics and Society · Physics 2021-07-26 Wesley Cota , David Soriano-Paños , Alex Arenas , Silvio C. Ferreira , Jesús Gómez-Gardeñes