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Adverse drug reactions (ADR) are widely concerning for public health issue. In this study we propose an original approach to detect ADRs using a feature matrix and feature selection. The experiments are carried out on the drug Simvastatin.…
This paper claims that a new field of empirical software engineering research and practice is emerging: data mining using/used-by optimizers for empirical studies or DUO. For example, data miners can generate models that are explored by…
Inferring causal relationships from observational data is often challenging due to endogeneity. This paper provides new identification results for causal effects of discrete, ordered and continuous treatments using multiple binary…
Randomised controlled trials (RCTs) are the most effective approach to causal discovery, but in many circumstances it is impossible to conduct RCTs. Therefore observational studies based on passively observed data are widely accepted as an…
A fundamental problem in data fusion is to determine the veracity of multi-source data in order to resolve conflicts. While previous work in truth discovery has proved to be useful in practice for specific settings, sources' behavior or…
Building robust online content recommendation systems requires learning complex interactions between user preferences and content features. The field has evolved rapidly in recent years from traditional multi-arm bandit and collaborative…
While deep convolutional neural networks (CNNs) are vulnerable to adversarial attacks, considerably few efforts have been paid to construct robust deep tracking algorithms against adversarial attacks. Current studies on adversarial attack…
Data mining is wide spreading its applications in several areas. There are different tasks in mining which provides solutions for wide variety of problems in order to discover knowledge. Among those tasks association mining plays a pivotal…
Warfarin, a commonly prescribed drug to prevent blood clots, has a highly variable individual response. Determining a maintenance warfarin dose that achieves a therapeutic blood clotting time, as measured by the international normalized…
Identification of drug-target interactions is an indispensable part of drug discovery. While conventional shallow machine learning and recent deep learning methods based on chemogenomic properties of drugs and target proteins have pushed…
In longitudinal studies using routinely collected data, such as electronic health records (EHRs), patients tend to have more measurements when they are unwell; this informative observation pattern may lead to bias. While semi-parametric…
Pharmacovigilance and clinical decision support systems utilize structured drug safety data to guide medical practice. However, existing datasets frequently depend on terminologies such as MedDRA, which limits their semantic reasoning…
Combining experimental and observational follow-up datasets has received a lot of attention lately. In a time-to-event setting, recent work has used medicare claims to extend the follow-up period for participants in a prostate cancer…
Longitudinal network consists of a sequence of temporal edges among multiple nodes, where the temporal edges are observed in real time. It has become ubiquitous with the rise of online social platform and e-commerce, but largely…
Long-term causal inference has drawn increasing attention in many scientific domains. Existing methods mainly focus on estimating average long-term causal effects by combining long-term observational data and short-term experimental data.…
Complementary and alternative medicine are commonly used concomitantly with conventional medications leading to adverse drug reactions and even fatality in some cases. Furthermore, the vast possibility of herb-drug interactions prevents…
Long-term outcomes are often unavailable in randomized clinical trials, although short-term surrogate outcomes are commonly observed. External observational data may contain the long-term outcome, but causal comparisons based on such data…
Joint models for longitudinal and time-to-event data are commonly used in longitudinal studies to forecast disease trajectories over time. While there are many advantages to joint modeling, the standard forms suffer from limitations that…
In recent years, many methods have been developed for detecting causal relationships in observational data. Some of them have the potential to tackle large data sets. However, these methods fail to discover a combined cause, i.e. a…
The exponential growth of data in current times and the demand to gain information and knowledge from the data present new challenges for database researchers. Known database systems and algorithms are no longer capable of effectively…