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Tandem mass spectrometry (MS/MS) is a high-throughput technology used toidentify the proteins in a complex biological sample, such as a drop of blood. A collection of spectra is generated at the output of the process, each spectrum of which…

Quantitative Methods · Quantitative Biology 2019-09-06 John T. Halloran , David M. Rocke

Diffusion distillation, exemplified by Distribution Matching Distillation (DMD), has shown great promise in few-step generation but often sacrifices quality for sampling speed. While integrating Reinforcement Learning (RL) into distillation…

Machine Learning · Computer Science 2026-04-22 Linwei Dong , Ruoyu Guo , Ge Bai , Zehuan Yuan , Yawei Luo , Changqing Zou

Atomistic simulation methods have evolved through successive computational levels, each building upon more fundamental approaches: from quantum mechanics to density functional theory (DFT), and subsequently, to machine learning interatomic…

Machine learning tasks involving biomedical signals frequently grapple with issues such as limited data availability, imbalanced datasets, labeling complexities, and the interference of measurement noise. These challenges often hinder the…

Signal Processing · Electrical Eng. & Systems 2024-01-30 Xiaomin Li , Mykhailo Sakevych , Gentry Atkinson , Vangelis Metsis

Diffusion models generate high-quality images but require dozens of forward passes. We introduce Distribution Matching Distillation (DMD), a procedure to transform a diffusion model into a one-step image generator with minimal impact on…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Tianwei Yin , Michaël Gharbi , Richard Zhang , Eli Shechtman , Fredo Durand , William T. Freeman , Taesung Park

We consider the estimation of Dirichlet Process Mixture Models (DPMMs) in distributed environments, where data are distributed across multiple computing nodes. A key advantage of Bayesian nonparametric models such as DPMMs is that they…

Machine Learning · Statistics 2017-09-20 Ruohui Wang , Dahua Lin

Synthetic microbiomes offer new possibilities for modulating microbiota, to address the barriers in multidtug resistance (MDR) research. We present a Bayesian optimization approach to enable efficient searching over the space of synthetic…

Quantitative Methods · Quantitative Biology 2024-05-02 Nisha Pillai , Bindu Nanduri , Michael J Rothrock , Zhiqian Chen , Mahalingam Ramkumar

Fueled by applications in sensor networks, these years have witnessed a surge of interest in distributed estimation and filtering. A new approach is hereby proposed for the Distributed Kalman Filter (DKF) by integrating a local covariance…

Systems and Control · Computer Science 2017-03-17 Ye Yuan , Ling Shi , Jun Liu , Zhiyong Chen , Hai-Tao Zhang , Jorge Goncalves

In this paper, we introduce DistDD, a novel approach within the federated learning framework that reduces the need for repetitive communication by distilling data directly on clients' devices. Unlike traditional federated learning that…

Machine Learning · Computer Science 2024-10-14 Peiran Wang , Haohan Wang

In this work, we present the first algorithm for identifying the minimum reboiler vapor duty requirement for a general multi-feed, multi-product (MFMP) distillation column separating ideal multicomponent mixtures. This algorithm…

Optimization and Control · Mathematics 2025-10-31 Zheyu Jiang , Mohit Tawarmalani , Rakesh Agrawal

In the realm of unsupervised learning, Bayesian nonparametric mixture models, exemplified by the Dirichlet Process Mixture Model (DPMM), provide a principled approach for adapting the complexity of the model to the data. Such models are…

Machine Learning · Computer Science 2022-04-20 Or Dinari , Raz Zamir , John W. Fisher , Oren Freifeld

Biomedical and biochemical processes in paper-based microfluidic devices often deal with mixing of two analytes to perform important functions. Uniform mixing of analytes in paper matrix is a challenging proposition, often necessitating…

Dataset distillation has emerged as a powerful approach for reducing data requirements in deep learning. Among various methods, distribution matching-based approaches stand out for their balance of computational efficiency and strong…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Shaobo Wang , Yicun Yang , Zhiyuan Liu , Chenghao Sun , Xuming Hu , Conghui He , Linfeng Zhang

The miniaturization and integration of electronic circuitry has not only made the enormous increase in performance of semiconductor devices possible but also spawned a myriad of new products and applications ranging from a cellular phone to…

Fluid Dynamics · Physics 2011-03-16 A. Rathgeber , C. Strobl , H. -J. Kutschera , A. Wixforth

Machine learning optimization often depends on stochastic gradient descent, where the precision of gradient estimation is vital for model performance. Gradients are calculated from mini-batches formed by uniformly selecting data samples…

Machine Learning · Computer Science 2025-01-29 Corentin Salaün , Xingchang Huang , Iliyan Georgiev , Niloy J. Mitra , Gurprit Singh

The task of dataset distillation aims to find a small set of synthetic images such that training a model on them reproduces the performance of the same model trained on a much larger dataset of real samples. Existing distillation methods…

Computer Vision and Pattern Recognition · Computer Science 2025-11-21 George Cazenavette , Antonio Torralba , Vincent Sitzmann

Micro/nanoporous membranes have been used extensively in biological and medical applications associated with filtration, particle sorting, cell separation, and real-time sensing. Expanding its applications to microfluidics offers several…

We develop a novel parallel resampling algorithm for fully parallelized particle filters, which is designed with GPUs (graphics processing units) or similar parallel computing devices in mind. With our new algorithm, a full cycle of…

Computation · Statistics 2016-08-17 Kenichiro McAlinn , Teruo Nakatsuma

With the development of deep convolutional neural networks, medical image segmentation has achieved a series of breakthroughs in recent years. However, the high-performance convolutional neural networks always mean numerous parameters and…

Computer Vision and Pattern Recognition · Computer Science 2022-08-30 Wenxuan Zou , Muyi Sun

Block Floating Point (BFP) arithmetic is currently seeing a resurgence in interest because it requires less power, less chip area, and is less complicated to implement in hardware than standard floating point arithmetic. This paper explores…

Numerical Analysis · Mathematics 2023-07-04 Nils Kohl , Stephen F. McCormick , Rasmus Tamstorf