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Many biochemical and industrial applications involve complicated networks of simultaneously occurring chemical reactions. Under the assumption of mass action kinetics, the dynamics of these chemical reaction networks are governed by systems…

Dynamical Systems · Mathematics 2014-07-15 Matthew D. Johnston

The global dynamics of gene regulatory networks are known to show robustness to perturbations in the form of intrinsic and extrinsic noise, as well as mutations of individual genes. One molecular mechanism underlying this robustness has…

Molecular Networks · Quantitative Biology 2015-06-15 Claus Kadelka , David Murrugarra , Reinhard Laubenbacher

A mathematical model for a two-gene regulatory network is derived and several of their properties analyzed. Due to the presence of mixed continuous/discrete dynamics and hysteresis, we employ a hybrid systems model to capture the dynamics…

Systems and Control · Computer Science 2014-02-04 Qin Shu , Ricardo G. Sanfelice

In this paper we study the dynamical behavior of Boolean networks with firing memory, namely Boolean networks whose vertices are updated synchronously depending on their proper Boolean local transition functions so that each vertex remains…

Discrete Mathematics · Computer Science 2022-04-25 Eric Goles , Fabiola Lobos , Gonzalo A. Ruz , Sylvain Sené

Boolean networks are discrete dynamical systems where each automaton has its own Boolean function for computing its state according to the configuration of the network. The updating mode then determines how the configuration of the network…

Dynamical Systems · Mathematics 2021-06-30 Loïc Paulevé , Sylvain Sené

We analyse the equilibrium behaviour and non-equilibrium dynamics of sparse Boolean networks with self-interactions that evolve according to synchronous Glauber dynamics. Equilibrium analysis is achieved via a novel application of the…

Disordered Systems and Neural Networks · Physics 2022-10-19 Christian John Hurry , Alexander Mozeika , Alessia Annibale

Boolean network (BN) is a simple model widely used to study complex dynamic behaviour of biological systems. Nonetheless, it might be difficult to gather enough data to precisely capture the behavior of a biological system into a set of…

Molecular Networks · Quantitative Biology 2020-09-02 Lubos Brim , Samuel Pastva , David Safranek , Eva Smijakova

The dynamical behavior of networked systems is expected to reflect the features of their coupling structure. Yet, symmetry-broken solutions often occur in symmetrically coupled networks. An example is provided by the so-called solitary…

Pattern Formation and Solitons · Physics 2022-11-30 Leonhard Schülen , Maria Mikhailenko , Everton S. Medeiros , Anna Zakharova

The theory of complex networks and of disordered systems is used to study the stability and dynamical properties of a simple model of material flow networks defined on random graphs. In particular we address instabilities that are…

Disordered Systems and Neural Networks · Physics 2009-11-13 Kartik Anand , Tobias Galla

In the context of discrete dynamical systems and their applications, fixed points often have a clear interpretation. This is indeed a central topic of gene regulatory mechanisms modeled by Boolean automata networks (BANs), where a…

Discrete Mathematics · Computer Science 2025-07-29 Kévin Perrot , Sylvain Sené , Léah Tapin

Living systems are often described utilizing informational analogies. An important open question is whether information is merely a useful conceptual metaphor, or intrinsic to the operation of biological systems. To address this question,…

Molecular Networks · Quantitative Biology 2015-08-19 Hyunju Kim , Paul Davies , Sara Imari Walker

The study of dynamical systems on complex networks is of paramount importance in engineering, given that many natural and artificial systems find a natural embedding on discrete topologies. For instance, power grids, chemical reactors and…

Optimization and Control · Mathematics 2024-04-26 Riccardo Muolo , Anthony Hastir , Hiroya Nakao

Switch-like responses arising from bistability have been linked to cell signaling processes and memory. Revealing the shape and properties of the set of parameters that lead to bistability is necessary to understand the underlying…

Molecular Networks · Quantitative Biology 2023-04-26 Máté L. Telek , Elisenda Feliu

Observabililty is an important topic of Boolean control networks (BCNs). In this paper, we propose a new type of observability named online observability to present the sufficient and necessary condition of determining the initial states of…

Systems and Control · Computer Science 2020-12-08 Guisen Wu , Liyun Dai , Zhiming Liu , Taolue Chen , Jun Pang

Random walks represent an important tool for probing the structural and dynamical properties of networks and modeling transport and diffusion processes on networks. However, when individuals' movement becomes dictated by more complicated…

Pattern Formation and Solitons · Physics 2022-11-24 Per Sebastian Skardal

This paper exploits bisimulation relations, generated by extracting the concept of morphisms between algebraic structures, to analyze set stabilization of Boolean control networks with lower complexity. First, for two kinds of bisimulation…

Optimization and Control · Mathematics 2024-12-25 Tiantian Mu , Jun-e Feng , Biao Wang

The problem on how to determine the observability of Boolean control networks (BCNs) has been open for five years already. In this paper, we propose a unified approach to determine all the four types of observability of BCNs in the…

Optimization and Control · Mathematics 2015-12-10 Kuize Zhang , Lijun Zhang

Recent progress in experimental techniques has enabled us to quantitatively study stochastic and flexible behavior of biological systems. For example, gene regulatory networks perform stochastic information processing and their…

Statistical Mechanics · Physics 2018-06-21 Shun Otsubo , Takahiro Sagawa

This paper proposes a new parameter for studying Boolean networks: the independence number. We establish that a Boolean network is $k$-independent if, for any set of $k$ variables and any combination of binary values assigned to them, there…

Combinatorics · Mathematics 2024-10-08 Julio Aracena , Raúl Astete-Elguin

Despite significant progress on stability analysis of conventional multiagent networked systems with weakly coupled state-network dynamics, most of the existing results have shortcomings in addressing multiagent systems with highly coupled…

Systems and Control · Electrical Eng. & Systems 2020-07-21 S. Rasoul Etesami
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