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Radiotherapy (RT) planning is complex, subjective, and time-intensive. Advances with artificial intelligence (AI) promise to improve its precision and efficiency, but progress is often limited by the scarcity of large, standardized…

Unrolled networks have been widely used for Magnetic Resonance Imaging (MRI) reconstruction due to their efficiency. However, they typically exhibit unstable output quality across cascades, resulting in sub-optimal final reconstruction…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Kehan Qi , Saumya Gupta , Xiaoling Hu , Qingqiao Hu , Weimin Lyu , Chao Chen

Neurodegenerative parkinsonism can be assessed by dopamine transporter single photon emission computed tomography (DaT-SPECT). Although generating images is time consuming, these images can show interobserver variability and they have been…

Computer Vision and Pattern Recognition · Computer Science 2021-05-10 Jun-En Ding , Chi-Hsiang Chu , Mong-Na Lo Huang , Chien-Ching Hsu

We propose a novel multi-task neural network approach for estimating distributional treatment effects (DTE) in randomized experiments. While DTE provides more granular insights into the experiment outcomes over conventional methods focusing…

Machine Learning · Computer Science 2025-07-11 Tomu Hirata , Undral Byambadalai , Tatsushi Oka , Shota Yasui , Shingo Uto

The main focus of image mining in the proposed method is concerned with the classification of brain tumor in the CT scan brain images. The major steps involved in the system are: pre-processing, feature extraction, association rule mining…

Computer Vision and Pattern Recognition · Computer Science 2010-03-25 P. Rajendran , M. Madheswaran

Treatment planning, which is a critical component of the radiotherapy workflow, is typically carried out by a medical physicist in a time-consuming trial-and-error manner. Previous studies have proposed knowledge-based or…

Image and Video Processing · Electrical Eng. & Systems 2024-03-29 Yiwen Zhang , Chuanpu Li , Liming Zhong , Zeli Chen , Wei Yang , Xuetao Wang

Radiation therapy treatment planning can be viewed as an iterative hyperparameter tuning process to balance conflicting clinical goals. In this work, we investigated the performance of modern Bayesian Optimization (BO) methods on automated…

Medical Physics · Physics 2023-02-15 Qingying Wang , Ruoxi Wang , Jiacheng Liu , Fan Jiang , Haizhen Yue , Yi Du , Hao Wu

In the treatment plan optimization for intensity modulated radiation therapy (IMRT), dose-deposition coefficient (DDC) matrix is often pre-computed to parameterize the dose contribution to each voxel in the volume of interest from each…

Medical Physics · Physics 2013-03-15 Zhen Tian , Masoud Zarepisheh , Xun Jia , Steve B. Jiang

Determining the optimal initial dose for warfarin is a critically important task. Several factors have an impact on the therapeutic dose for individual patients, such as patients' physical attributes (Age, Height, etc.), medication profile,…

Machine Learning · Computer Science 2019-03-25 Ashkan Sharabiani , Adam Bress , William Galanter , Rezvan Nazempour , Houshang Darabi

Background: Proton arc therapy is an emerging radiation therapy technique where either the gantry or the patient continuously rotates during the irradiation treatment. One of the perceived advantages of proton arc therapy is the reduced…

Medical Physics · Physics 2023-10-20 Viktor Wase , Otte Marthin , Albin Fredriksson , Anton Finnson

Saliency maps have been widely used to interpret deep learning classifiers for Alzheimer's disease (AD). However, since AD is heterogeneous and has multiple subtypes, the pathological mechanism of AD remains not fully understood and may…

Computer Vision and Pattern Recognition · Computer Science 2024-07-12 Yihan Zhang , Xuanshuo Zhang , Wei Wu , Haohan Wang

Random access is necessary in crowded scenarios due to the limitation of pilot sequences and the intermittent pattern of device activity. Nowadays, most of the related works are based on independent and identically distributed (i.i.d.)…

Signal Processing · Electrical Eng. & Systems 2019-08-19 Junyuan Gao , Yongpeng Wu , Fan Wei

Background and purpose: In-beam Positron Emission Tomography (PET) is one of the modalities that can be used for in-vivo non-invasive treatment monitoring in proton therapy. PET distributions obtained during various treatment sessions can…

Causal inference methods for treatment effect estimation usually assume independent units. However, this assumption is often questionable because units may interact, resulting in spillover effects between them. We develop augmented inverse…

Methodology · Statistics 2025-04-08 Corinne Emmenegger , Meta-Lina Spohn , Timon Elmer , Peter Bühlmann

More than 13 million people suffer from ischemic cerebral stroke worldwide each year. Thrombolytic treatment can reduce brain damage but has a narrow treatment window. Computed Tomography Perfusion imaging is a commonly used primary…

Image and Video Processing · Electrical Eng. & Systems 2021-04-22 Luca Tomasetti , Kjersti Engan , Mahdieh Khanmohammadi , Kathinka Dæhli Kurz

Randomized controlled trials are the standard method for estimating causal effects, ensuring sufficient statistical power and confidence through adequate sample sizes. However, achieving such sample sizes is often challenging. This study…

Methodology · Statistics 2025-03-28 Keisuke Hanada , Masahiro Kojima

Learning-based fluence map prediction offers a fast alternative to iterative inverse planning in intensity-modulated radiation therapy (IMRT), but its robustness under realistic distribution shifts remains unclear. We study a two-stage…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Ujunwa Mgboh , Rafi Ibn Sultan , Joshua Kim , Kundan Thind , Dongxiao Zhu

The planar-diagrammatic technique of large-$N$ random matrices is extended to evaluate averages over the circular ensemble of unitary matrices. It is then applied to study transport through a disordered metallic ``grain'', attached through…

Condensed Matter · Physics 2009-10-28 N. Argaman , A. Zee

Machine learning (ML) estimates of conditional average treatment effects (CATE) can guide policy decisions, either by allowing targeting of individuals with beneficial CATE estimates, or as inputs to decision trees that optimise overall…

Econometrics · Economics 2023-10-04 Julia Hatamyar , Noemi Kreif

Noncoplanar radiation therapy treatment planning has the potential to improve dosimetric quality as compared to traditional coplanar techniques. Likewise, automated treatment planning algorithms can reduce a planner's active treatment…

Medical Physics · Physics 2022-01-19 Charles Huang , Yong Yang , Lei Xing
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