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In medical imaging, chromosome straightening plays a significant role in the pathological study of chromosomes and in the development of cytogenetic maps. Whereas different approaches exist for the straightening task, typically geometric…

Computer Vision and Pattern Recognition · Computer Science 2021-10-20 Sifan Song , Daiyun Huang , Yalun Hu , Chunxiao Yang , Jia Meng , Fei Ma , Frans Coenen , Jiaming Zhang , Jionglong Su

Subspace clustering is a classical technique that has been widely used for human motion segmentation and other related tasks. However, existing segmentation methods often cluster data without guidance from prior knowledge, resulting in…

Computer Vision and Pattern Recognition · Computer Science 2022-02-11 Tao Zhou , Huazhu Fu , Chen Gong , Ling Shao , Fatih Porikli , Haibin Ling , Jianbing Shen

The probability of two loci, separated by a certain genome length, being in contact can be inferred using the Chromosome Conformation Capture (3C) method and related Hi-C experiments. How to go from the contact map, a matrix listing the…

Soft Condensed Matter · Physics 2021-03-24 Guang Shi , D. Thirumalai

We describe a strategy for detection and classification of man-made objects in large high-resolution satellite photos under computational resource constraints. We detect and classify candidate objects by using five pipelines of…

Computer Vision and Pattern Recognition · Computer Science 2018-10-25 Gilbert Rotich , Rodrigo Minetto , Sudeep Sarkar

Researchers developed chromosome capture methods such as Hi-C to better understand DNA's 3D folding in nuclei. The Hi-C method captures contact frequencies between DNA segment pairs across the genome. When analyzing Hi-C data sets, it is…

Physics and Society · Physics 2023-11-14 Dolores Bernenko , Sang Hoon Lee , Ludvig Lizana

The antibody repertoire of each individual is continuously updated by the evolutionary process of B cell receptor mutation and selection. It has recently become possible to gain detailed information concerning this process through…

Populations and Evolution · Quantitative Biology 2015-05-11 Connor O. McCoy , Trevor Bedford , Vladimir N. Minin , Philip Bradley , Harlan Robins , Frederick A. Matsen

We investigate the localization property of an electron in the disordered two-chain system (ladder model) with long-range correlation as a simple model for electronic property in DNA sequence. The chains are constructed by repetition of the…

Disordered Systems and Neural Networks · Physics 2009-11-10 Hiroaki Yamada

Artificial intelligence (AI) has introduced numerous opportunities for human assistance and task automation in medicine. However, it suffers from poor generalization in the presence of shifts in the data distribution. In the context of…

The Consecutive-Ones Property (C1P) is a classical concept in discrete mathematics that has been used in several genomics applications, from physical mapping of contemporary genomes to the assembly of ancient genomes. A common issue in…

Data Structures and Algorithms · Computer Science 2013-06-21 Cedric Chauve , Murray Patterson , Ashok Rajaraman

DNA data storage offers a high-density, long-term alternative to traditional storage systems, addressing the exponential growth of digital data. Composite DNA extends this paradigm by leveraging mixtures of nucleotides to increase storage…

Information Theory · Computer Science 2026-02-13 Busra Tegin , Tolga M Duman

Motivation: Thanks to the recent advances in structural biology, nowadays three-dimensional structures of various proteins are solved on a routine basis. A large portion of these contain structural repetitions or internal symmetries. To…

Quantitative Methods · Quantitative Biology 2018-10-30 Guillaume Pagès , Sergei Grudinin

Galaxy clusters appear as extended sources in XMM-Newton images, but not all extended sources are clusters. So, their proper classification requires visual inspection with optical images, which is a slow process with biases that are almost…

The XMM Cluster Archive Super Survey (X-CLASS) is a serendipitously-detected X-ray-selected sample of 845 galaxy clusters based on 2774 XMM archival observations and covering approximately 90 deg$^2$ spread across the high-Galactic latitude…

Cosmology and Nongalactic Astrophysics · Physics 2017-04-12 J. Ridl , N. Clerc , T. Sadibekova , L. Faccioli , F. Pacaud , J. Greiner , T. Krühler , A. Rau , M. Salvato , M. -L. Menzel , H. Steinle , P. Wiseman , K. Nandra , J. Sanders

We present the compilation and properties of a Meta-Catalogue of X-ray detected Clusters of galaxies, the MCXC. This very large catalogue is based on publicly available ROSAT All Sky Survey-based (NORAS, REFLEX, BCS, SGP, NEP, MACS, and…

Cosmology and Nongalactic Astrophysics · Physics 2015-05-19 R. Piffaretti , M. Arnaud , G. W. Pratt , E. Pointecouteau , J. -B. Melin

RNAnet provides a bridge between two widely used Human gene databases. Ensembl describes DNA sequences and transcripts but not experimental gene expression. Whilst NCBI's GEO contains actual expression levels from Human samples. RNAnet…

Molecular Networks · Quantitative Biology 2010-01-26 W. B. Langdon , Olivia Sanchez Graillet , A. P. Harrison

DNA-based storage offers unprecedented density and durability, but its scalability is fundamentally limited by the efficiency of parallel strand synthesis. Existing methods either allow unconstrained nucleotide additions to individual…

Information Theory · Computer Science 2025-10-27 Boaz Moav , Ryan Gabrys , Eitan Yaakobi

Although theories regarding the role of sequence-specific DNA resonance in biology have abounded for over 40 years, the published evidence for it is lacking. Here, the authors reasoned that for sustained resonance signaling, the number of…

Other Quantitative Biology · Quantitative Biology 2019-10-28 Ivan Savelev , Max Myakishev-Rempel

Complex spatial and temporal patterns of gene expression underlie embryo differentiation, yet methods do not yet exist for the efficient genome-wide determination of spatial expression patterns during development. In situ imaging of…

Genomics · Quantitative Biology 2013-08-15 Peter A. Combs , Michael B. Eisen

The intra- and inter-species genetic diversity of bacteria and the absence of 'reference', or the most representative, sequences of individual species present a significant challenge for sequence-based identification. The aims of this study…

Genomics · Quantitative Biology 2023-12-01 Manal Helal , Fanrong Kong , Sharon C. A. Chen , Michael Bain , Richard Christen , Vitali Sintchenko

The upcoming XMM Large Scale Structure Survey (XMM-LSS) will ultimately provide a unique mapping of the distribution of X-ray sources in a contiguous 64 sq. deg. region. In particular, it will provide the 3-dimensional location of about 900…

Astrophysics · Physics 2009-11-07 Alexandre Refregier , Ivan Valtchanov , Marguerite Pierre