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The fluid dynamics video presented here outlines recent advances in the simulation of multiphase cellular blood flow through the direct numerical simulations of deformable red blood cells (RBCs) demonstrated through several numerical…

Fluid Dynamics · Physics 2010-10-18 Daniel A. Reasor , Jonathan R. Clausen , Brian M. Yun , Cyrus K. Aidun

One-dimensional (1D) blood flow simulations are extensively used in cardiovascular research due to their computational efficiency and effectiveness in analyzing pulse wave dynamics. Despite their versatility and simplicity, there is a lack…

Quantitative Methods · Quantitative Biology 2025-08-27 Daehyun Kim , Jeffrey Tithof

Biological cells utilize membranes and liquid-like droplets, known as biomolecular condensates, to structure their interior. The interaction of droplets and membranes, despite being involved in several key biological processes, is so far…

Soft Condensed Matter · Physics 2024-02-21 Marcel Mokbel , Dominic Mokbel , Susanne Liese , Christoph A. Weber , Sebastian Aland

We illustrate the potential of PDE-based traffic flow control in cardiovascular flow analysis, monitoring, and control, presenting a PDE-based control-oriented formulation, for 1-D blood flow dynamics in the presence of stenosis. This is…

Optimization and Control · Mathematics 2021-12-23 Nikolaos Bekiaris-Liberis

Event-driven molecular dynamics simulations are carried out on two rigid body systems which differ in the symmetry of their molecular mass distributions. First, simulations of methane in which the molecules interact via discontinuous…

Statistical Mechanics · Physics 2007-05-23 Lisandro Hernandez de la Pena , Ramses van Zon , Jeremy Schofield , Sheldon B. Opps

Many of the intriguing properties of blood originate from its cellular nature. Bulk effects, such as viscosity, depend on the local shear rates and on the size of the vessels. While empirical descriptions of bulk rheology are available for…

Computational Engineering, Finance, and Science · Computer Science 2023-05-05 Gabor Zavodszky , Christian Spieker , Benjamin Czaja , Britt van Rooij

This study aims at finding a method for constructing molecular dynamics like models using the formalism of cellular automata for fast simulation of fluid dynamic systems (including compressible phenomena). In as much as the results…

comp-gas · Physics 2009-09-25 Himanshu Agrawal

High-resolution blood flow simulations have potential for developing better understanding biophysical phenomena at the microscale, such as vasodilation, vasoconstriction and overall vascular resistance. To this end, we present a scalable…

Computational Engineering, Finance, and Science · Computer Science 2019-09-26 Libin Lu , Matthew J. Morse , Abtin Rahimian , Georg Stadler , Denis Zorin

Cardiac disease and clinical intervention may both lead to an increased risk for thrombosis events due to modified blood flow in the heart, and thereby a change in the mechanical stimuli of blood cells passing through the chambers of the…

Methods of Computational Fluid Dynamics are applied to simulate pulsatile blood flow in human vessels and in the aortic arch. The non-Newtonian behaviour of the human blood is investigated in simple vessels of actual size. A detailed…

Computational Physics · Physics 2008-02-19 Renat A. Sultanov , Dennis Guster , Brent Engelbrekt , Richard Blankenbecler

We use molecular dynamics simulations to study the evaporation of particle-laden droplets on a heated surface. The droplets are composed of a Lennard-Jones fluid containing rigid particles which are spherical sections of an atomic lattice,…

Soft Condensed Matter · Physics 2015-06-04 Weikang Chen , Joel Koplik , Ilona Kretzschmar

In this work, we present mixed dimensional models for simulating blood flow and transport processes in breast tissue and the vascular tree supplying it. These processes are considered, to start from the aortic inlet to the capillaries and…

Tissues and Organs · Quantitative Biology 2022-10-10 Marvin Fritz , Tobias Köppl , J. Tinsley Oden , Andreas Wagner , Barbara Wohlmuth , Chengyue Wu

We report computational results of blood flow through a model of the human aortic arch and a vessel of actual diameter and length. On the top of the aortic arch the branching of the %%three arteries are included: the subclavian and jugular.…

Fluid Dynamics · Physics 2008-11-11 Renat A. Sultanov , Dennis Guster

This paper presents a novel particle method to compute strongly coupled incompressible fluid and rigid bodies. The method adopts a velocity-based formulation and utilizes the linear complementarity problem for the incompressibility…

Fluid Dynamics · Physics 2023-03-01 Shugo Miyamoto , Seiichi Koshizuka

Particle methods play an important role in computational fluid dynamics, but they are among the most difficult to implement and solve. The most common method is smoothed particle hydrodynamics, which is suitable for problem settings that…

Fluid Dynamics · Physics 2025-08-26 Masato Shibukawa , Naoya Ozaki , Maximilien Berthet

We study the settling of solid particles within a viscous incompressible fluid contained in a two-dimensional channel, where the mass density of the particles is slightly greater than that of the fluid. The fluid-structure interaction…

Fluid Dynamics · Physics 2015-09-07 Sudeshna Ghosh , John M. Stockie

Many biological examples of fluid-structure interaction, including the transit of red blood cells through the narrow slits in the spleen and the intracellular trafficking of vesicles into dendritic spines, involve the near-contact of…

Numerical Analysis · Mathematics 2017-12-20 Thomas G. Fai , Chris H. Rycroft

The dynamics and rheology of suspensions of fluid vesicles or red blood cells is investigated by a combination of molecular dynamics and mesoscale hydrodynamics simulations in two dimensions. The vesicle suspension is confined between two…

Soft Condensed Matter · Physics 2013-05-03 A. Lamura , G. Gompper

Around the third week after gestation in embryonic development, the human heart consists only of a valvless tube, unlike a fully developed adult heart, which is multi-chambered. At this stage in development, the heart valves have not formed…

Tissues and Organs · Quantitative Biology 2018-09-19 Nicholas A. Battista , Andrea N. Lane , Laura A. Miller

Flux of rigid or soft particles (such as drops, vesicles, red blood cells, etc.) in a channel is a complex function of particle concentration, which depends on the details of induced dissipation and suspension structure due to hydrodynamic…