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Current theoretical and computational models of dopamine-based reinforcement learning are largely rooted in the classical behaviorist tradition, and envision the organism as a purely reactive recipient of rewards and punishments, with…

Neurons and Cognition · Quantitative Biology 2014-05-01 Randall C. O'Reilly , Thomas E. Hazy , Jessica Mollick , Prescott Mackie , Seth Herd

Network control theory has recently emerged as a promising approach for understanding brain function and dynamics. By operationalizing notions of control theory for brain networks, it offers a fundamental explanation for how brain dynamics…

Quantitative Methods · Quantitative Biology 2020-03-20 Shikuang Deng , Shi Gu

The glow of a starry night sky, the smell of a freshly brewed cup of coffee or the sound of ocean waves breaking on the beach are representations of the physical world that have been created by the dynamic interactions of thousands of…

Neurons and Cognition · Quantitative Biology 2011-07-28 Henry Lütcke , Fritjof Helmchen

What is the relationship between brain and behavior? The answer to this question necessitates characterizing the mapping between structure and function. The aim of this paper is to discuss broad issues surrounding the link between structure…

Neurons and Cognition · Quantitative Biology 2015-06-19 Luiz Pessoa

It takes several years for the developing brain of a baby to fully master word repetition-the task of hearing a word and repeating it aloud. Repeating a new word, such as from a new language, can be a challenging task also for adults.…

Computation and Language · Computer Science 2025-06-17 Daniel Dager , Robin Sobczyk , Emmanuel Chemla , Yair Lakretz

Traditional approaches to understanding the brain's resilience to neuropathology have identified neurophysiological variables, often described as brain or cognitive 'reserve,' associated with better outcomes. However, mechanisms of function…

Neurons and Cognition · Quantitative Biology 2017-01-18 John D. Medaglia , Fabio Pasqualetti , Roy H. Hamilton , Sharon L. Thompson-Schill , Danielle S. Bassett

Ageing impacts the brain's structural and functional organization and over time leads to various disorders, such as Alzheimer's disease and cognitive impairment. The process also impacts sensory function, bringing about a general slowing in…

Neurons and Cognition · Quantitative Biology 2022-09-07 L. J. Fosque , A. Alipour , M. Zare , R. V. Williams-Garcia , J. M. Beggs , G. Ortiz

Modern neuroscience has accumulated extensive evidence on perception, memory, prediction, valuation, and consciousness, yet still lacks an explicit operational architecture capable of integrating these phenomena within a unified…

Neurons and Cognition · Quantitative Biology 2026-03-17 Ionel Cristian Vladu , Nicu Bizdoaca , Ionica Pirici , Tudor-Adrian Balseanu , Eduard Nicusor Bondoc

The brain is a complex organ characterized by heterogeneous patterns of structural connections supporting unparalleled feats of cognition and a wide range of behaviors. New noninvasive imaging techniques now allow these patterns to be…

Neurons and Cognition · Quantitative Biology 2020-04-03 Christopher W. Lynn , Danielle S. Bassett

Codifying memories is one of the fundamental problems of modern Neuroscience. The functional mechanisms behind this phenomenon remain largely unknown. Experimental evidence suggests that some of the memory functions are performed by…

Neurons and Cognition · Quantitative Biology 2022-05-17 Ivan Y. Tyukin , Alexander N. Gorban , Carlos Calvo , Julia Makarova , Valeri A. Makarov

Representation is a key notion in neuroscience and artificial intelligence (AI). However, a longstanding philosophical debate highlights that specifying what counts as representation is trickier than it seems. With this brief opinion paper…

Artificial Intelligence · Computer Science 2022-04-21 Eloy Parra-Barrero , Yulia Sandamirskaya

We present a computational and theoretical model of the neural mechanisms underlying human decision-making. We propose a detailed model of the interaction between brain regions, under a proposer-predictor-actor-critic framework.…

Neurons and Cognition · Quantitative Biology 2019-12-18 Seth Herd , Kai Krueger , Ananta Nair , Jessica Mollick , Randall OReilly

The cognitive functions of human and non-human primates rely on the dynamic interplay of distributed neural assemblies. As such, it seems unlikely that cognition can be supported by macroscopic brain dynamics at the proximity of…

The ability to form memories is a basic feature of learning and accumulating knowledge. But where is memory information stored in the brain? Within the scientific research community, it is generally believed that memory information is…

Neurons and Cognition · Quantitative Biology 2024-03-28 Jie Zhang

The cerebral cortex spontaneously displays different patterns of activity that evolve over time according to the brain state. Sleep, wakefulness, resting states, and attention are examples of a wide spectrum of physiological states that can…

The coding mechanism of sensory memory on the neuron scale is one of the most important questions in neuroscience. We have put forward a quantitative neural network model, which is self organized, self similar, and self adaptive, just like…

Neural and Evolutionary Computing · Computer Science 2014-06-26 Peilei Liu , Ting Wang

When we experience an event, it feels like our previous experiences, our interpretations of that event (e.g., aesthetics, emotions), and our current state will determine how we will remember it. However, recent work has revealed a strong…

Neurons and Cognition · Quantitative Biology 2021-04-15 Wilma A. Bainbridge

The brain is immensely complex, with diverse components and dynamic interactions building upon one another to orchestrate a wide range of functions and behaviors. Understanding patterns of these complex interactions and how they are…

Neurons and Cognition · Quantitative Biology 2024-08-06 Suman Kulkarni , Dani S. Bassett

Memory plays a foundational role in augmenting the reasoning, adaptability, and contextual fidelity of modern Large Language Models and Multi-Modal LLMs. As these models transition from static predictors to interactive systems capable of…

Artificial Intelligence · Computer Science 2026-01-15 Zixia Jia , Jiaqi Li , Yipeng Kang , Yuxuan Wang , Tong Wu , Quansen Wang , Xiaobo Wang , Shuyi Zhang , Junzhe Shen , Qing Li , Siyuan Qi , Yitao Liang , Di He , Zilong Zheng , Song-Chun Zhu

We consider the implications of the mathematical analysis of neurone-to-neurone dynamical complex networks. We show how the dynamical behaviour of small scale strongly connected networks lead naturally to non-binary information processing…

Neurons and Cognition · Quantitative Biology 2016-09-15 Peter Grindrod