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Adaptive behavior, cognition and emotion are the result of a bewildering variety of brain spatiotemporal activity patterns. An important problem in neuroscience is to understand the mechanism by which the human brain's 100 billion neurons…

Neurons and Cognition · Quantitative Biology 2011-05-09 Paul Expert , Renaud Lambiotte , Dante R. Chialvo , Kim Christensen , Henrik Jeldtoft Jensen , David J. Sharp , Federico Turkheimer

A fundamental understanding of the network architecture of the brain is necessary for the further development of theories explicating circuit function. Perhaps as a derivative of its initial application to abstract informational systems,…

Neurons and Cognition · Quantitative Biology 2018-07-13 Jennifer Stiso , Danielle Bassett

Magnetoencephalography, the noninvasive measurement of magnetic fields produced by brain activity, utilizes quantum sensors such as superconducting quantum interference devices and atomic magnetometers. Combining the energy resolution limit…

Biological Physics · Physics 2026-03-06 E. Gkoudinakis , S. Li , I. K. Kominis

With the wide adoption of functional magnetic resonance imaging (fMRI) by cognitive neuroscience researchers, large volumes of brain imaging data have been accumulated in recent years. Aggregating these data to derive scientific insights…

Applications · Statistics 2020-06-01 Ming Bo Cai , Michael Shvartsman , Anqi Wu , Hejia Zhang , Xia Zhu

Neural electrical activity is fundamental to brain function, underlying a range of cognitive and behavioral processes, including movement, perception, decision-making, and consciousness. Abnormal patterns of neural signaling often indicate…

Neurons and Cognition · Quantitative Biology 2025-09-03 Zhizhang Yuan , Fanqi Shen , Meng Li , Yuguo Yu , Chenhao Tan , Yang Yang

The neural mechanism of memory has a very close relation with the problem of representation in artificial intelligence. In this paper a computational model was proposed to simulate the network of neurons in brain and how they process…

Neurons and Cognition · Quantitative Biology 2020-12-02 Hui Wei

We show that scaling arguments are very useful to analyze the dynamics of periodically modulated noisy systems. Information about the behavior of the relevant quantities, such as the signal-to-noise ratio, upon variations of the noise…

Statistical Mechanics · Physics 2016-08-15 J. M. G. Vilar , J. M. Rubí

Common measures of neural representational (dis)similarity are designed to be insensitive to rotations and reflections of the neural activation space. Motivated by the premise that the tuning of individual units may be important, there has…

Machine Learning · Computer Science 2023-11-17 Meenakshi Khosla , Alex H. Williams

Our knowledge of the sensory world is encoded by neurons in sequences of discrete, identical pulses termed action potentials or spikes. There is persistent controversy about the extent to which the precise timing of these spikes is relevant…

Neurons and Cognition · Quantitative Biology 2007-05-23 Ilya Nemenman , Geoffrey D. Lewen , William Bialek , Rob R. de Ruyter van Steveninck

Perceptions and actions, thoughts and memories result from coordinated activity in hundreds or even thousands of neurons in the brain. It is an old dream of the physics community to provide a statistical mechanics description for these and…

Disordered Systems and Neural Networks · Physics 2024-09-04 Leenoy Meshulam , William Bialek

Many deep architectures and self-supervised pre-training techniques have been proposed for human activity recognition (HAR) from wearable multimodal sensors. Scaling laws have the potential to help move towards more principled design by…

Machine Learning · Computer Science 2025-05-22 Tom Hoddes , Alex Bijamov , Saket Joshi , Daniel Roggen , Ali Etemad , Robert Harle , David Racz

In the brain, neural activity undergoes directed flows between states, thus breaking time-reversal symmetry. At the same time, animals also exhibit irreversible flows between behavioral states. Yet it remains unclear whether -- and how --…

Neurons and Cognition · Quantitative Biology 2026-01-12 Kaiyue Shi , Christopher W. Lynn

The study of plasticity in spiking neural networks is an active area of research. However, simulations that involve complex plasticity rules, dense connectivity/high synapse counts, complex neuron morphologies, or extended simulation times…

Neural and Evolutionary Computing · Computer Science 2024-12-05 Philipp Spilger , Eric Müller , Johannes Schemmel

Backpropagation-optimized artificial neural networks, while precise, lack robustness, leading to unforeseen behaviors that affect their safety. Biological neural systems do solve some of these issues already. Unlike artificial models,…

Neural and Evolutionary Computing · Computer Science 2025-02-04 Konstantin Holzhausen , Mia Merlid , Håkon Olav Torvik , Anders Malthe-Sørenssen , Mikkel Elle Lepperød

Starting from the concept of binary interactions between pairs of particles, a kinetic framework for the description of the action potential dynamics on a neural network is proposed. It consists of two coupled levels: the description of a…

Biological Physics · Physics 2023-03-21 Martina Conte , Maria Groppi , Andrea Tosin

Physical limit of molecular sensing has been extensively studied in biological systems. Biosensors are engineered equivalents of molecular sensors in living systems and play critical role in disease diagnosis and management. Investigation…

Biological Physics · Physics 2021-08-10 Tuhin Chakrabortty , Manoj M Varma

Intracranial recordings in epilepsy patients are increasingly utilized to gain insight into the electrophysiological mechanisms of human cognition. There are currently several practical limitations to conducting research with these…

Neurons and Cognition · Quantitative Biology 2021-06-23 Omer E Ashmaig , Liberty S Hamilton , Pradeep Modur , Robert J Buchanan , Alison R Preston , Andrew J Watrous

Current magnetic resonance imaging (MRI) requires the subject to remain stationary to limit motion artifacts and avoid unwanted field-induced brain stimulation. However, imaging during large-scale motion could enable studies in which motion…

Full scale simulations of neuronal network models of the brain are challenging due to the high density of connections between neurons. This contribution reports run times shorter than the simulated span of biological time for a full scale…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-10-04 Anno C. Kurth , Johanna Senk , Dennis Terhorst , Justin Finnerty , Markus Diesmann

Neural systems can be modeled as networks of functionally connected neural elements. The resulting network can be analyzed using mathematical tools from network science and graph theory to quantify the system's topological organization and…

Neurons and Cognition · Quantitative Biology 2020-07-01 Richard F. Betzel , Katherine C. Wood , Christopher Angeloni , Maria Neimark Geffen , Danielle S. Bassett