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We consider the optimal experimental design problem of allocating subjects to treatment or control when subjects participate in multiple, separate controlled experiments within a short time-frame and subject covariate information is…

Methodology · Statistics 2024-12-16 William Fisher , Qiong Zhang , Lulu Kang , Xinwei Deng

In this paper, we derive optimal designs for the Rasch Poisson counts model and the Rasch Poisson-Gamma counts model incorporating several binary predictors for the difficulty parameter. To efficiently estimate the regression coefficients…

Methodology · Statistics 2021-04-07 Ulrike Graßhoff , Heinz Holling , Rainer Schwabe

Principal component analysis and factor analysis are fundamental multivariate analysis methods. In this paper a unified framework to connect them is introduced. Under a general latent variable model, we present matrix optimization problems…

Methodology · Statistics 2024-05-31 Shifeng Xiong

In this work we present the results of several simulations on main-effect factorial designs. The goal of such simulations is to investigate the connections between the $D$-optimality of a design and its geometrical structure. By means of a…

Computation · Statistics 2016-04-18 Roberto Fontana , Fabio Rapallo

In experimental design, we are given $n$ vectors in $d$ dimensions, and our goal is to select $k\ll n$ of them to perform expensive measurements, e.g., to obtain labels/responses, for a linear regression task. Many statistical criteria have…

Machine Learning · Computer Science 2019-06-11 Michał Dereziński , Feynman Liang , Michael W. Mahoney

Given a positive definite covariance matrix $\widehat \Sigma$, we strive to construct an optimal \emph{approximate} factor analysis model $HH^\top +D$, with $H$ having a prescribed number of columns and $D>0$ diagonal. The optimality…

Probability · Mathematics 2023-02-27 Lorenzo Finesso , Peter Spreij

Locally optimal designs for generalized linear models are derived at certain values of the regression parameters. In the present paper a general setup of the generalized linear model is considered. Analytic solutions for optimal designs are…

Statistics Theory · Mathematics 2019-06-06 Osama Idais

The modal factor model represents a new factor model for dimension reduction in high dimensional panel data. Unlike the approximate factor model that targets for the mean factors, it captures factors that influence the conditional mode of…

Econometrics · Economics 2024-10-01 Zhe Sun , Yundong Tu

A class of nonlinear models combining a pharmacokinetic compartmental model and a pharmacodynamic Emax model is introduced. The locally D-optimal (LD) design for a four-parameter composed model is found to be a saturated four-point uniform…

Methodology · Statistics 2008-12-18 X. Fang , A. S. Hedayat

We consider the problem of constructing optimal designs for model discrimination between competing regression models. Various new properties of optimal designs with respect to the popular $T$-optimality criterion are derived, which in many…

Statistics Theory · Mathematics 2009-08-14 Holger Dette , Stefanie Titoff

We present a new approach to the design of D-optimal experiments with multivariate polynomial regressions on compact semi-algebraic design spaces. We apply the moment-sum-of-squares hierarchy of semidefinite programming problems to solve…

Statistics Theory · Mathematics 2017-03-07 Yohann De Castro , F Gamboa , D Henrion , R Hess , J. -B Lasserre

Two-level factorial designs are widely used in industrial experiments. For processes involving \(n\) factors, the construction of designs comprising \(2^n\) and \(2^{n-p}\) factorials, arranged in blocks of size \(2^q\) is investigated. The…

Statistics Theory · Mathematics 2019-07-05 Janet Godolphin

We study the optimal design problem under second-order least squares estimation which is known to outperform ordinary least squares estimation when the error distribution is asymmetric. First, a general approximate theory is developed,…

Statistics Theory · Mathematics 2014-05-14 Mausumi Bose , Rahul Mukerjee

To address efficiency and design challenges in choice-based matching platforms, we introduce a two-sided assortment optimization framework under general choice preferences. The goal in this problem is to maximize the expected number of…

Optimization and Control · Mathematics 2026-05-08 Omar El Housni , Ulysse Hennebelle , Alfredo Torrico

Row-column factorial designs that provide unconfounded estimation of all main effects and the maximum number of two-factor interactions (2fi's) are called 2fi-optimal. This issue has been paid great attention recently for its wide…

Statistics Theory · Mathematics 2023-08-02 Yingnan Zhang , Jiangmin Pan , Lei Shi

Optimal designs can help experimenters obtain more accurate parameter estimates with reduced experimental time and cost. In this paper, we characterize the Expected Weighted (EW) D-optimal designs as robust designs against unknown parameter…

Methodology · Statistics 2026-04-08 Siting Lin , Yifei Huang , Jie Yang

Alternating direction methods of multipliers (ADMMs) are popular approaches to handle large scale semidefinite programs that gained attention during the past decade. In this paper, we focus on solving doubly nonnegative programs (DNN),…

Optimization and Control · Mathematics 2020-09-15 Martina Cerulli , Marianna De Santis , Elisabeth Gaar , Angelika Wiegele

In this paper, we address the problem of designing an experimental plan with both discrete and continuous factors under fairly general parametric statistical models. We propose a new algorithm, named ForLion, to search for locally optimal…

Computation · Statistics 2024-05-24 Yifei Huang , Keren Li , Abhyuday Mandal , Jie Yang

The subject of this work is two treatment groups random coefficient regression models, in which observational units receive some group-specific treatments. We provide A- and D-optimality criteria for the estimation of the fixed parameter…

Statistics Theory · Mathematics 2020-08-11 Maryna Prus

With the help of Generalized Estimating Equations, we identify locally D-optimal crossover designs for generalized linear models. We adopt the variance of parameters of interest as the objective function, which is minimized using…

Methodology · Statistics 2023-09-11 Jeevan Jankar , Jie Yang , Abhyuday Mandal