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Group testing is a long studied problem in combinatorics: A small set of $r$ ill people should be identified out of the whole ($n$ people) by using only queries (tests) of the form "Does set X contain an ill human?". In this paper we…

Data Structures and Algorithms · Computer Science 2008-04-29 Ely Porat , Amir Rothschild

Two-phase sampling is commonly adopted for reducing cost and improving estimation efficiency. In many two-phase studies, the outcome and some cheap covariates are observed for a large sample in Phase I, and expensive covariates are obtained…

Methodology · Statistics 2025-10-14 Qingning Zhou , Kin Yau Wong

In this paper, we propose algorithms that leverage a known community structure to make group testing more efficient. We consider a population organized in connected communities: each individual participates in one or more communities, and…

Information Theory · Computer Science 2021-03-18 Pavlos Nikolopoulos , Sundara Rajan Srinivasavaradhan , Tao Guo , Christina Fragouli , Suhas Diggavi

In this paper, we describe a two-stage method for solving optimization problems with bound constraints. It combines the active-set estimate described in [Facchinei and Lucidi, 1995] with a modification of the non-monotone line search…

Optimization and Control · Mathematics 2016-11-08 Andrea Cristofari , Marianna De Santis , Stefano Lucidi , Francesco Rinaldi

Latent class models are widely used for identifying unobserved subgroups from multivariate categorical data in social sciences, with binary data as a particularly popular example. However, accurately recovering individual latent class…

Methodology · Statistics 2026-02-25 Zhongyuan Lyu , Yuqi Gu

In group testing, the task is to determine the distinguished members of a set of objects L by asking subset queries of the form ``does the subset Q of L contain a distinguished object?'' The primary biological application of group testing…

Combinatorics · Mathematics 2008-02-03 Emanuel Knill , S. Muthukrishnan

In this paper, we propose an efficient two-stage decoding algorithm for non-adaptive Group Testing (GT) with general correlated prior statistics. The proposed solution can be applied to any correlated statistical prior represented in…

Information Theory · Computer Science 2026-03-03 Ayelet C. Portnoy , Amit Solomon , Alejandro Cohen

In group testing, the goal is to identify a subset of defective items within a larger set of items based on tests whose outcomes indicate whether at least one defective item is present. This problem is relevant in areas such as medical…

Information Theory · Computer Science 2022-10-24 Eric Price , Jonathan Scarlett , Nelvin Tan

The study in group testing aims to develop strategies to identify a small set of defective items among a large population using a few pooled tests. The established techniques have been highly beneficial in a broad spectrum of applications…

Information Theory · Computer Science 2025-01-23 Venkata Gandikota , Nikita Polyanskii , Haodong Yang

In small sample studies with binary outcome data, use of a normal approximation for hypothesis testing can lead to substantial inflation of the type-I error-rate. Consequently, exact statistical methods are necessitated, and accordingly,…

Methodology · Statistics 2017-11-29 Michael Grayling , Adrian Mander , James Wason

The goal of combinatorial group testing is to efficiently identify up to $d$ defective items in a large population of $n$ items, where $d \ll n$. Defective items satisfy certain properties while the remaining items in the population do not.…

Information Theory · Computer Science 2019-04-02 Thach V. Bui , Minoru Kuribayashi , Mahdi Cheraghchi , Isao Echizen

In a high dimensional regression setting in which the number of variables ($p$) is much larger than the sample size ($n$), the number of possible two-way interactions between the variables is immense. If the number of variables is in the…

Methodology · Statistics 2024-06-26 Marianne A Jonker , Luc van Schijndel , Eric Cator

Biological machine learning is often bottlenecked by a lack of scaled data. One promising route to relieving data bottlenecks is through high throughput screens, which can experimentally test the activity of $10^6-10^{12}$ protein sequences…

Machine Learning · Statistics 2025-10-21 Eli N. Weinstein , Andrei Slabodkin , Mattia G. Gollub , Elizabeth B. Wood

We describe an implementation of a genetic algorithm on partially commutative groups and apply it to the double coset search problem on a subclass of groups. This transforms a combinatorial group theory problem to a problem of combinatorial…

Group Theory · Mathematics 2007-05-23 Matthew Craven

The experimenter must perform a legitimate search in the entire set of feasible censoring schemes to identify the optimal type II progressive censoring scheme, when applied to a life-testing experiment. Current recommendations are limited…

Applications · Statistics 2025-07-29 Ujjwal Roy , Ritwik Bhattacharya

In the group testing problem the aim is to identify a small set of $k\sim n^\theta$ infected individuals out of a population size $n$, $0<\theta<1$. We avail ourselves of a test procedure capable of testing groups of individuals, with the…

Discrete Mathematics · Computer Science 2021-05-14 Amin Coja-Oghlan , Oliver Gebhard , Max Hahn-Klimroth , Philipp Loick

Inspired by recent results from collusion-resistant traitor tracing, we provide a framework for constructing efficient probabilistic group testing schemes. In the traditional group testing model, our scheme asymptotically requires T ~ 2 K…

Information Theory · Computer Science 2014-04-11 Thijs Laarhoven

In the group testing problem we aim to identify a small number of infected individuals within a large population. We avail ourselves to a procedure that can test a group of multiple individuals, with the test result coming out positive iff…

Discrete Mathematics · Computer Science 2021-05-14 Amin Coja-Oghlan , Oliver Gebhard , Max Hahn-Klimroth , Philipp Loick

High-throughput screening (HTS) is a large-scale hierarchical process in which a large number of chemicals are tested in multiple stages. Conventional statistical analyses of HTS studies often suffer from high testing error rates and…

Applications · Statistics 2017-07-13 Tao Feng , Pallavi Basu , Wenguang Sun , Hsun Teresa Ku , Wendy J. Mack

We introduce the Genetic-Gated Networks (G2Ns), simple neural networks that combine a gate vector composed of binary genetic genes in the hidden layer(s) of networks. Our method can take both advantages of gradient-free optimization and…

Neural and Evolutionary Computing · Computer Science 2019-03-06 Simyung Chang , John Yang , Jaeseok Choi , Nojun Kwak