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Detection of false-positive motifs is one of the main causes of low performance in motif finding methods. It is generally assumed that false-positives are mostly due to algorithmic weakness of motif-finders. Here, however, we derive the…

Genomics · Quantitative Biology 2010-12-23 Amin Zia , Alan M. Moses

As the anti-viruses run in a trusted kernel level any loophole in the anti-virus program can enable attackers to take full control over the computer system and steal data or do serious damages. Hence the anti-virus engines must be developed…

Cryptography and Security · Computer Science 2013-07-23 Umakant Mishra

Positivity is one of the three conditions for causal inference from observational data. The standard way to validate positivity is to analyze the distribution of propensity. However, to democratize the ability to do causal inference by…

Machine Learning · Computer Science 2021-11-09 Guy Wolf , Gil Shabat , Hanan Shteingart

We review the fingerprinting scheme by Tardos and show that it has a much better performance than suggested by the proofs in Tardos' original paper. In particular, the length of the codewords can be significantly reduced. First we…

Cryptography and Security · Computer Science 2008-06-03 B. Skoric , T. U. Vladimirova , M. Celik , J. C. Talstra

Random numbers play a crucial role in science and industry. Many numerical methods require the use of random numbers, in particular the Monte Carlo method. Therefore it is of paramount importance to have efficient random number generators.…

Computational Physics · Physics 2010-05-25 Helmut G. Katzgraber

Industry practitioners care about small improvements in malware detection accuracy because their models are deployed to hundreds of millions of machines, meaning a 0.1\% change can cause an overwhelming number of false positives. However,…

Machine Learning · Computer Science 2023-12-27 Tirth Patel , Fred Lu , Edward Raff , Charles Nicholas , Cynthia Matuszek , James Holt

Consider the problem of simultaneously testing null hypotheses H_1,...,H_s. The usual approach to dealing with the multiplicity problem is to restrict attention to procedures that control the familywise error rate (FWER), the probability of…

Statistics Theory · Mathematics 2007-06-13 E. L. Lehmann , Joseph P. Romano

Positive and negative likelihood ratios are parameters which are used to assess and compare the effectiveness of binary diagnostic tests. Both parameters only depend on the sensitivity and specificity of the diagnostic test and are…

Other Statistics · Statistics 2024-09-02 Jose Antonio Roldan-Nofuentes , Saad Bouh Sidaty-Regad

Distinguishing abnormal nodes from those with normal packet loss in clusters helps reduce the loss of clustered network resources. The detection performance of existing detection schemes is limited by the techniques to quantify node…

Systems and Control · Electrical Eng. & Systems 2025-05-14 Yingying Huangfu , Tian Bai

A new method based on the rejection sampling for finding statistical tests is proposed. This method is conceptually intuitive, easy to implement, and applicable for arbitrary dimension. To illustrate its potential applicability, three…

Methodology · Statistics 2026-03-11 Markku Kuismin

Obtaining datasets labeled to facilitate model development is a challenge for most machine learning tasks. The difficulty is heightened for medical imaging, where data itself is limited in accessibility and labeling requires costly time and…

Computation and Language · Computer Science 2018-10-03 Nithya Attaluri , Ahmed Nasir , Carolynne Powe , Harold Racz , Ben Covington , Li Yao , Jordan Prosky , Eric Poblenz , Tobi Olatunji , Kevin Lyman

Multiple testing problems are a staple of modern statistical analysis. The fundamental objective of multiple testing procedures is to reject as many false null hypotheses as possible (that is, maximize some notion of power), subject to…

Methodology · Statistics 2020-11-30 Saharon Rosset , Ruth Heller , Amichai Painsky , Ehud Aharoni

In research on eye movements in reading, it is common to analyze a number of canonical dependent measures to study how the effects of a manipulation unfold over time. Although this gives rise to the well-known multiple comparisons problem,…

Applications · Statistics 2016-10-11 Titus von der Malsburg , Bernhard Angele

We develop a new approach to multi-label conformal prediction in which we aim to output a precise set of promising prediction candidates with a bounded number of incorrect answers. Standard conformal prediction provides the ability to adapt…

Machine Learning · Computer Science 2022-02-16 Adam Fisch , Tal Schuster , Tommi Jaakkola , Regina Barzilay

We analyze different types of simulations that applied researchers can use to assess whether their inference methods reliably control false-positive rates. We show that different assessments involve trade-offs, varying in the types of…

Econometrics · Economics 2025-10-03 Bruno Ferman

The accuracy of published medical research is critical both for scientists, physicians and patients who rely on these results. But the fundamental belief in the medical literature was called into serious question by a paper suggesting most…

Applications · Statistics 2013-01-17 Leah R. Jager , Jeffrey T. Leek

Dynamic languages are praised for their flexibility and expressiveness, but static analysis often yields many false positives and verification is cumbersome for lack of structure. Hence, unit testing is the prevalent incomplete method for…

Programming Languages · Computer Science 2015-02-06 Robert Jakob , Peter Thiemann

Classification is a fundamental task in many applications on which data-driven methods have shown outstanding performances. However, it is challenging to determine whether such methods have achieved the optimal performance. This is mainly…

Machine Learning · Computer Science 2024-01-30 Minoh Jeong , Martina Cardone , Alex Dytso

Testing symptomatic individuals for a disease can deliver treatment resources, if tests' results turn positive, which speeds up their treatment and might also decrease individuals' contacts to other ones. An imperfect test, however, might…

Populations and Evolution · Quantitative Biology 2015-06-25 Daniel A. M. Villela

Instance segmentation of images is an important tool for automated scene understanding. Neural networks are usually trained to optimize their overall performance in terms of accuracy. Meanwhile, in applications such as automated driving, an…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Kira Maag