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Understanding protein folding has been one of the great challenges in biochemistry and molecular biophysics. Over the past 50 years, many thermodynamic and kinetic studies have been performed addressing the stability of globular proteins.…

Biomolecules · Quantitative Biology 2014-04-01 Ernesto A. Roman , F. Luis Gonzalez Flecha

Sliding of two-dimensional materials is critical for their application as solid lubricants for space, and also relevant for strain engineering and device fabrication. Dopants such as Ni surprisingly improve lubrication in MoS$_2$, despite…

Materials Science · Physics 2022-10-03 Enrique Guerrero , David A. Strubbe

In this paper, we mathematically describe the time evolution of protein folding features via Iori et al.'s heteropolymer model. More specifically, we identify that the folding amino acid chain evolve according to a power law $D \sim…

Dynamical Systems · Mathematics 2026-04-22 Okezue Bell

Polyampholytes (PA) are charged polymers composed of positively and negatively charged monomers along their backbone. The sequence of the charged monomers and the bending of the chain significantly influence the conformation and dynamical…

Soft Condensed Matter · Physics 2024-08-29 Rakesh Palariya , Sunil P. Singh

The transport of polymers with folded configurations across membrane pores is investigated theoretically by analyzing simple discrete stochastic models. The translocation dynamics is viewed as a sequence of two events: motion of the folded…

Statistical Mechanics · Physics 2009-11-13 Stanislav Kotsev , Anatoly B. Kolomeisky

We consider the rupture dynamics of a homopolymer chain pulled at one end at a constant loading rate r. Compared to single bond breaking, the existence of the chain introduces two new aspects into rupture dynamics: the non-Markovian aspect…

Soft Condensed Matter · Physics 2009-10-29 S. Fugmann , I. M. Sokolov

Mechanical unfolding of several domains of calmodulin and titin is studied using a Go-like model with a realistic contact map and Lennard-Jones contact interactions. It is shown that this simple model captures the experimentally observed…

Biomolecules · Quantitative Biology 2009-11-10 Marek Cieplak

The porous titanium nickelide is very popular in various industries due to unique combination of physical and mechanical properties such as shape memory effect, high corrosion resistance, and biocompatibility. The non-equilibrium molecular…

Materials Science · Physics 2021-05-17 Bulat N. Galimzyanov , Anatolii V. Mokshin

Mixtures of polymers of varying topologies and stiffnesses display complex emergent rheological properties that often cannot be predicted from their single-component counterparts. For example, entangled blends of ring and linear polymers…

Soft Condensed Matter · Physics 2022-11-23 Karthik R. Peddireddy , Ryan Clairmont , Rae M. Robertson-Anderson

The effects of entanglement in solutions and melts of unknotted ring polymers have been addressed by several theoretical and numerical studies. The system properties have been typically profiled as a function of ring contour length at fixed…

Soft Condensed Matter · Physics 2011-11-29 Angelo Rosa , Enzo Orlandini , Luca Tubiana , Cristian Micheletti

Molecular valves are becoming popular for potential biomedical applications. However, little is known concerning their performance in energy and environmental areas. Zeolite RHO shows unique pore deformations upon changes in hydration,…

We have carried out experiments to probe the static and dynamic interfacial properties of $\beta$--casein monolayers spread at the air-buffer interface, and analysed these results in the context of models of weak polyampholytes.…

Soft Condensed Matter · Physics 2009-11-07 Pietro Cicuta , Ian Hopkinson

The dynamics and structural characteristics of polymethacrylic acid bound rhodamine-123 (PMAAR123) and its interpolymer complex with poly(vinylpyrrolidone) were investigated using single molecular fluorescence studies. The time resolved…

Chemical Physics · Physics 2020-02-25 K. Durai Murugan

The knowledge of how oxygen atoms are distributed at a magnetic-metal / oxide, or magnetic-metal / non-magnetic-metal interface, can be an useful tool to optimize device production. Multilayered Ni81Fe19 / Ta samples consisting of 15…

Materials Science · Physics 2021-11-15 T. J. A. Mori , R. D. D. Pace , W. H. Flores , M. Carara , L. F. Schelp , L. S. Dorneles

Thermal unfolding of proteins is compared to folding and mechanical stretching in a simple topology-based dynamical model. We define the unfolding time and demonstrate its low-temperature divergence. Below a characteristic temperature,…

Biomolecules · Quantitative Biology 2009-11-13 Marek Cieplak , Joanna I. Sulkowska

The functioning of machines typically requires a concerted action of their parts. This requirement also holds for molecular motors that drive vital cellular processes and imposes constraints on their conformational changes as well as the…

Biological Physics · Physics 2022-06-14 Zena Hadjivasiliou , Karsten Kruse

We consider a lattice model of a semiflexible homopolymer chain in a bad solvent. Beside the temperature $T$, this model is described by (i) a curvature energy $\varepsilon_h$, representing the stiffness of the chain (ii) a…

Condensed Matter · Physics 2009-10-28 S. Doniach , T. Garel , H. Orland

I develop a kinetic mechanism to explain chain folding in polymer crystallization which is based on the competition between the formation of stems, which is due to frequent occupations of trans states along the chains in the supercooled…

Soft Condensed Matter · Physics 2014-09-23 S. Stepanow

We present results from extensive molecular dynamics simulations of collapse transitions of hydrophobic polymers in explicit water focused on understanding effects of lengthscale of the hydrophobic surface and of attractive interactions on…

Statistical Mechanics · Physics 2007-05-23 Manoj V. Athawale , Gaurav Goel , Tuhin Ghosh , Thomas M. Truskett , Shekhar Garde

Crosslinked semi-flexible and flexible filaments that are actively deformed by molecular motors occur in various natural settings, such as the ordered eukaryotic flagellum, and the disordered cytoskeleton. The deformation of these composite…

Biological Physics · Physics 2018-10-02 Arvind Gopinath , Raghunath Chelakkot , L. Mahadevan