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Biological tissue imaging by secondary ion mass spectrometry has seen rapid development with the commercial availability of polyatomic primary ion sources. Endogenous lipids and other small bio-molecules can now be routinely mapped on the…

Instrumentation and Detectors · Physics 2013-06-05 Donald F. Smith , Andras Kiss , Franklin E. Leach , Errol W. Robinson , Ljiljana Paša-Tolić , Ron M. A. Heeren

Mass Spectrometry (MS) is a largely used analytical technique in biology with applications such as the determination of molecule masses or the elucidation of structural data. Fourier Transform Ion Cyclotron Resonance MS is one…

Chemical Physics · Physics 2019-06-17 Laura Duciel , Afef Cherni , Marc-André Delsuc

Broadband precision spectroscopy is indispensable for providing high fidelity molecular parameters for spectroscopic databases. We have recently shown that mechanical Fourier transform spectrometers based on optical frequency combs can…

Instrumentation and Detectors · Physics 2018-05-09 Lucile Rutkowski , Piotr Maslowski , Alexandra C. Johansson , Amir Khodabakhsh , Aleksandra Foltynowicz

Optical frequency-comb-based-high-resolution spectrometers offer enormous potential for spectroscopic applications. Although various implementations have been demonstrated, the lack of suitable mid-infrared comb sources has impeded…

Single-ion mass identification is important for atomic and nuclear physics experiments on ions produced with low yields. Cooling the ion to ultra-low temperatures by interacting with a laser-cooled ion will enhance the precision of the…

Astronomical spectrographs require frequency calibration through sources like hollow-cathode lamps or absorption-gas cells. Laser frequency combs (LFCs) provide highest accuracy but are facing operational challenges. We aim to provide a…

Instrumentation and Methods for Astrophysics · Physics 2024-09-05 Ansgar Reiners , Michael Debus , Sebastian Schäfer , Eberhard Tiemann , Mathias Zechmeister

Fourier transform spectroscopy based on incoherent light sources is a well-established tool in research fields from molecular spectroscopy and atmospheric monitoring to material science and biophysics. It provides broadband molecular…

Fourier-transform infrared spectroscopy (FTIR) is a powerful analytical method for not only the chemical identification of solid, liquid, and gas species, but also the quantification of their concentration. However, the chemical…

With the recent implementation of a radio-frequency quadrupole (RFQ) cooler-buncher and a multi-step laser resonance ionization technique, our previously developed collinear laser spectroscopy setup has been successfully upgraded into a…

Instrumentation and Detectors · Physics 2025-05-22 H. R. Hu , Y. F. Guo , X. F. Yang , Z. Yan , W. C. Mei , S. J. Chen , Y. S. Liu , P. Zhang , S. W. Bai , D. Y. Chen , Y. C. Liu , S. J. Wang , Q. T. Li , Y. L. Ye , C. Y. He , J. Yang , Z. Y. Liu

We demonstrate broadband and sensitive cavity ring-down spectroscopy using a near infrared frequency comb and a time-resolved Fourier transform spectrometer. The cavity decays are measured simultaneously and spectrally sorted, leading to…

Optics · Physics 2022-01-28 Romain Dubreoucq , Lucile Rutkowski

We present a robust analysis code developed in the Python language and incorporating libraries of the ROOT data analysis framework for the state-of-the-art mass spectrometry method called phase-imaging ion-cyclotron-resonance (PI-ICR). A…

Computational Physics · Physics 2021-07-28 Jonas Karthein , Dinko Atanasov , Klaus Blaum , David Lunney , Vladimir Manea , Maxime Mougeot

Methods to visualize the two-dimensional distribution of molecules by mass spectrometric imaging evolve rapidly and yield novel applications in biology, medicine, and material surface sciences. Most mass spectrometric imagers acquire high…

Instrumentation and Detectors · Physics 2011-03-11 Casimir Bamberger , Uwe Renz , Andreas Bamberger

Femtosecond interferometry combined with acousto-optical phase modulation is an effective approach to implement various types of coherent nonlinear and multidimensional spectroscopy schemes. The high sensitivity of this method has recently…

Atomic Physics · Physics 2025-02-24 Friedemann Landmesser , Nicolai Gölz , Ulrich Bangert , Tobias Sixt , Lukas Bruder

Measurement of low power infrared light emission spectra from microstructures can be challenging, but is of key importance in several research fields. Fourier transform infrared spectrometers (FTIR) can be used for characterizing such weak…

Optics · Physics 2025-11-18 Maxime Brazeau , Mathieu Giroux , Nada Boubrik , Raphael St-Gelais

Non-thermal molecular plasmas play a crucial role in numerous industrial processes and hold significant potential for driving essential chemical transformations. Accurate information about the molecular composition of the plasmas and the…

Fourier transform (FT) spectroscopy is a versatile technique for studying the infrared (IR) optical response of solid-, liquid-, and gas-phase samples. In standard FT-IR spectrometers, a light beam passing through a Michelson interferometer…

Applied Physics · Physics 2021-03-12 Takashi Kuroda , Siti Chalimah , Yuanzhao Yao , Naoki Ikeda , Yoshimasa Sugimoto , Kazuaki Sakoda

Sonography techniques use multiple transducer elements for tissue visualization. Signals detected at each element are sampled prior to digital beamforming. The required sampling rates are up to 4 times the Nyquist rate of the signal and…

Information Theory · Computer Science 2012-12-21 T. Chernyakova , Y. C. Eldar , R. Amit

Fourier ptychographic microscopy (FPM) is a pivotal computational imaging technique that achieves phase and amplitude reconstruction with high resolution and wide field of view, using low numerical aperture objectives and LED array…

Sonography techniques use multiple transducer elements for tissue visualization. Signals detected at each element are sampled prior to digital beamforming. The sampling rates required to perform high resolution digital beamforming are…

Information Theory · Computer Science 2013-07-25 Tanya Chernyakova , Yonina C. Eldar

We demonstrate a new computational illumination technique that achieves large space-bandwidth-time product, for quantitative phase imaging of unstained live samples in vitro. Microscope lenses can have either large field of view (FOV) or…

Optics · Physics 2015-10-16 Lei Tian , Ziji Liu , Li-Hao Yeh , Michael Chen , Jingshan Zhong , Laura Waller
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