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The exponential growth of neuroscientific data necessitates platforms that facilitate data management and multidisciplinary collaboration. In this paper, we introduce Pennsieve - an open-source, cloud-based scientific data management…

Computers and Society · Computer Science 2024-09-24 Zack Goldblum , Zhongchuan Xu , Haoer Shi , Patryk Orzechowski , Jamaal Spence , Kathryn A Davis , Brian Litt , Nishant Sinha , Joost Wagenaar

Accurately estimating the wiring diagram of a brain, known as a connectome, at an ultrastructure level is an open research problem. Specifically, precisely tracking neural processes is difficult, especially across many image slices. Here,…

Computer Vision and Pattern Recognition · Computer Science 2014-05-09 Ayushi Sinha , William Gray Roncal , Narayanan Kasthuri , Jeff W. Lichtman , Randal Burns , Michael Kazhdan

The human brain is a complex system defined by multi-way, higher-order interactions invisible to traditional pairwise network models. Although a diverse array of analytical methods has been developed to address this shortcoming, the field…

Quantitative Methods · Quantitative Biology 2025-11-11 Mohamma Reza Salehi , Ali BashirGonbadi , Hamid Soltanian-Zadeh

The rapid growth of data-intensive applications such as generative AI, scientific simulations, and large-scale analytics is driving modern supercomputers and data centers toward increasingly heterogeneous and tightly integrated…

A prominent goal of neuroimaging studies is mapping the human brain, in order to identify and delineate functionally-meaningful regions and elucidate their roles in cognitive behaviors. These brain regions are typically represented by…

Human-Computer Interaction · Computer Science 2020-09-04 Roza G. Bayrak , Nhung Hoang , Colin B. Hansen , Catie Chang , Matthew Berger

Clustering is a fundamental learning task widely used as a first step in data analysis. For example, biologists use cluster assignments to analyze genome sequences, medical records, or images. Since downstream analysis is typically…

Machine Learning · Computer Science 2024-06-11 Jonathan Svirsky , Ofir Lindenbaum

At this moment, databanks worldwide contain brain images of previously unimaginable numbers. Combined with developments in data science, these massive data provide the potential to better understand the genetic underpinnings of brain…

Machine Learning · Statistics 2025-01-30 Santiago Silva , Boris Gutman , Eduardo Romero , Paul M Thompson , Andre Altmann , Marco Lorenzi

In this article, we study association between the structural connectome and cognitive profiles using a multi-response nonparametric regression model.The cognitive profiles are measured in terms of seven age-adjusted cognitive test scores.…

Methodology · Statistics 2022-12-06 Arkaprava Roy

Early brain development is characterized by the formation of a highly organized structural connectome. The interconnected nature of this connectome underlies the brain's cognitive abilities and influences its response to diseases and…

Neurons and Cognition · Quantitative Biology 2023-08-24 Yihan Wu , Lana Vasung , Camilo Calixto , Ali Gholipour , Davood Karimi

Recently, a number of cloud platforms and services have been developed for data intensive computing, including Hadoop, Sector, CloudStore (formerly KFS), HBase, and Thrift. In order to benchmark the performance of these systems, to…

Distributed, Parallel, and Cluster Computing · Computer Science 2009-07-29 Robert Grossman , Yunhong Gu , Michal Sabala , Collin Bennet , Jonathan Seidman , Joe Mambratti

Distributed dataflow systems enable data-parallel processing of large datasets on clusters. Public cloud providers offer a large variety and quantity of resources that can be used for such clusters. Yet, selecting appropriate cloud…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-12-03 Jonathan Will , Lauritz Thamsen , Dominik Scheinert , Jonathan Bader , Odej Kao

We discuss computing issues for data analysis and image reconstruction of PET-TOF medical scanner or other medical scanning devices producing large volumes of data. Service architecture based on the grid and cloud concepts for distributed…

Multi-view clustering has become a significant area of research, with numerous methods proposed over the past decades to enhance clustering accuracy. However, in many real-world applications, it is crucial to demonstrate a clear…

Machine Learning · Computer Science 2025-02-07 Mudi Jiang , Lianyu Hu , Zengyou He , Zhikui Chen

Today, the human brain can be studied as a whole. Electroencephalography, magnetoencephalography, or functional magnetic resonance imaging techniques provide functional connectivity patterns between different brain areas, and during…

Data Analysis, Statistics and Probability · Physics 2011-01-21 Mario Chavez , Miguel Valencia , Vito Latora , Jacques Martinerie

For the past two decades, the DB community has devoted substantial research to take advantage of cheap clusters of machines for distributed data analytics -- we believe that we are at the beginning of a paradigm shift. The scaling laws and…

Databases · Computer Science 2025-08-05 Bowen Wu , Wei Cui , Carlo Curino , Matteo Interlandi , Rathijit Sen

Functional connectivity is a key approach to investigate oscillatory activities of the brain that provides important insights on the underlying dynamic of neuronal interactions and that is mostly applied for brain activity analysis.…

Neurons and Cognition · Quantitative Biology 2022-02-17 Marie-Constance Corsi , Sylvain Chevallier , Fabrizio De Vico Fallani , Florian Yger

Analyzing high-dimensional data and finding hidden patterns is a difficult problem and has attracted numerous research efforts. Automated methods can be useful to some extent but bringing the data analyst into the loop via interactive…

Human-Computer Interaction · Computer Science 2017-12-04 Bing Wang , Klaus Mueller

The connectomes of different human brains are pairwise distinct: we cannot talk about an abstract "graph of the brain". Two typical connectomes, however, have quite a few common graph edges that may describe the same connections between the…

Neurons and Cognition · Quantitative Biology 2015-01-07 Balazs Szalkai , Csaba Kerepesi , Balint Varga , Vince Grolmusz

Memory-compute disaggregation promises transparent elasticity, high utilization and balanced usage for resources in data centers by physically separating memory and compute into network-attached resource "blades". However, existing designs…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-10-22 Seung-seob Lee , Yanpeng Yu , Yupeng Tang , Anurag Khandelwal , Lin Zhong , Abhishek Bhattacharjee

High-performance computing (HPC) is essential for tackling complex computational problems across various domains. As the scale and complexity of HPC applications continue to grow, the need for scalable systems and software architectures…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-08-21 Risshab Srinivas Ramesh