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It is generally believed that bias is minimized in well-controlled randomized clinical trials. However, bias can arise in active controlled noninferiority trials because the inference relies on a previously estimated effect size obtained…

Applications · Statistics 2013-12-02 Lei Nie , Zhiwei Zhang , Daniel Rubin , Jianxiong Chu

This article considers the problem of estimating a multivariate probit model in a panel data setting with emphasis on sampling a high-dimensional correlation matrix and improving the overall efficiency of the data augmentation approach. We…

Computation · Statistics 2020-05-07 Vincent Chin , David Gunawan , Denzil G. Fiebig , Robert Kohn , Scott A. Sisson

We study variable selection (also called support recovery) in high-dimensional sparse linear regression when one has external information on which variables are likely to be associated with the response. Consistent recovery is only possible…

Statistics Theory · Mathematics 2026-02-16 Paul Rognon-Vael , David Rossell , Piotr Zwiernik

Whereas confidence intervals are used to assess uncertainty due to unmeasured individuals, confounding intervals can be used to assess uncertainty due to unmeasured attributes. Previously, we have introduced a methodology for computing…

Methodology · Statistics 2025-08-13 Brian Knaeble , R Mitchell Hughes

Sequential Multiple-Assignment Randomized Trials (SMARTs) play an increasingly important role in psychological and behavioral health research. This experimental approach enables researchers to answer scientific questions about how to…

Methodology · Statistics 2023-06-21 John J. Dziak , Daniel Almirall , Walter Dempsey , Catherine Stanger , Inbal Nahum-Shani

We review some aspects of Bayesian and frequentist interval estimation, focusing first on their relative strengths and weaknesses when used in "clean" or "textbook" contexts. We then turn attention to observational-data situations which are…

Methodology · Statistics 2010-10-05 Paul Gustafson , Sander Greenland

Data augmentation is a commonly applied technique with two seemingly related advantages. With this method one can increase the size of the training set generating new samples and also increase the invariance of the network against the…

Computer Vision and Pattern Recognition · Computer Science 2022-05-31 Jalal Al-afandi , Bálint Magyar , András Horváth

In most nonrandomized observational studies, differences between treatment groups may arise not only due to the treatment but also because of the effect of confounders. Therefore, causal inference regarding the treatment effect is not as…

Methodology · Statistics 2018-07-04 Debashis Ghosh

Longitudinal cohort studies, which follow a group of individuals over time, provide the opportunity to examine causal effects of complex exposures on long-term health outcomes. Utilizing data from multiple cohorts has the potential to add…

A common problem in health research is that we have a large database with many variables measured on a large number of individuals. We are interested in measuring additional variables on a subsample; these measurements may be newly…

Methodology · Statistics 2022-03-22 Thomas Lumley , Tong Chen

Experimental datasets are growing rapidly in size, scope, and detail, but the value of these datasets is limited by unwanted measurement noise. It is therefore tempting to apply analysis techniques that attempt to reduce noise and enhance…

Applications · Statistics 2022-07-12 Kendrick Kay

Large-scale prediction models using tools from artificial intelligence (AI) or machine learning (ML) are increasingly common across a variety of industries and scientific domains. Despite their effectiveness, training AI and ML tools at…

Methodology · Statistics 2025-01-09 Kentaro Hoffman , Stephen Salerno , Jeff Leek , Tyler McCormick

The paper illustrates an application of the Resampling approach [2] for the estimation of the aircraft circulation plan reliability. Resampling is an intensive computer statistical method, which can be used effectively in the case of small…

Applications · Statistics 2013-05-14 Maxim Fioshin

This paper presents Sparse Partitioning, a Bayesian method for identifying predictors that either individually or in combination with others affect a response variable. The method is designed for regression problems involving binary or…

Quantitative Methods · Quantitative Biology 2011-08-31 Doug Speed , Simon Tavaré

Many prediction tasks can admit multiple models that can perform almost equally well. This phenomenon can can undermine interpretability and safety when competing models assign conflicting predictions to individuals. In this work, we study…

Machine Learning · Computer Science 2025-08-01 Erin George , Deanna Needell , Berk Ustun

As a part of the Data-Centric AI Competition, we propose a data-centric approach to improve the diversity of the training samples by iterative sampling. The method itself relies strongly on the fidelity of augmented samples and the…

Machine Learning · Computer Science 2021-11-09 Devrim Cavusoglu , Ogulcan Eryuksel , Sinan Altinuc

Realizing when a model is right for a wrong reason is not trivial and requires a significant effort by model developers. In some cases an input salience method, which highlights the most important parts of the input, may reveal problematic…

Computation and Language · Computer Science 2023-01-12 Sebastian Ebert , Alice Shoshana Jakobovits , Katja Filippova

Machine learning models can capture and amplify biases present in data, leading to disparate test performance across social groups. To better understand, evaluate, and mitigate these biases, a deeper theoretical understanding of how model…

Machine Learning · Computer Science 2025-03-19 Arjun Subramonian , Samuel J. Bell , Levent Sagun , Elvis Dohmatob

Various strategies for active learning have been proposed in the machine learning literature. In uncertainty sampling, which is among the most popular approaches, the active learner sequentially queries the label of those instances for…

Machine Learning · Computer Science 2019-09-04 Vu-Linh Nguyen , Sébastien Destercke , Eyke Hüllermeier

In conventional randomized controlled trials, adjustment for baseline values of covariates known to be at least moderately associated with the outcome increases the power of the trial. Recent work has shown particular benefit for more…

Methodology · Statistics 2023-11-27 James Willard , Shirin Golchi , Erica EM Moodie