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The behavior of some stochastic chemical reaction networks is largely unaffected by slight inaccuracies in reaction rates. We formalize the robustness of state probabilities to reaction rate deviations, and describe a formal connection…

Computational Complexity · Computer Science 2009-01-28 David Soloveichik

Message passing algorithms have proved surprisingly successful in solving hard constraint satisfaction problems on sparse random graphs. In such applications, variables are fixed sequentially to satisfy the constraints. Message passing is…

Artificial Intelligence · Computer Science 2019-06-05 Andrea Montanari , Federico Ricci-Tersenghi , Guilhem Semerjian

We study here a natural situation when constraint programming can be entirely reduced to rule-based programming. To this end we explain first how one can compute on constraint satisfaction problems using rules represented by simple…

Artificial Intelligence · Computer Science 2007-05-23 Krzysztof R. Apt , Eric Monfroy

Chemical reaction network theory is a field of applied mathematics concerned with modeling chemical systems, and can be used in other contexts such as in systems biology to study cellular signaling pathways or epidemiology to study the…

Algebraic Geometry · Mathematics 2024-06-17 Maize Curiel , Elise Farr , Galileo Fries , Luis David García Puente , Julian Hutchins , Vuong Nguyen Hoang

For dynamical systems arising from chemical reaction networks, persistence is the property that each species concentration remains positively bounded away from zero, as long as species concentrations were all positive in the beginning. We…

Dynamical Systems · Mathematics 2016-07-29 Michael Marcondes de Freitas , Elisenda Feliu , Carsten Wiuf

The recently measured yeast transcriptional network is analyzed in terms of simplified Boolean network models, with the aim of determining feasible rule structures, given the requirement of stable solutions of the generated Boolean…

Molecular Networks · Quantitative Biology 2009-11-10 Stuart Kauffman , Carsten Peterson , Björn Samuelsson , Carl Troein

This paper depicts algorithms for solving the decision Boolean Satisfiability Problem. An extreme problem is formulated to analyze the complexity of algorithms and the complexity for solving it. A novel and easy reformulation as a lottery…

Computational Complexity · Computer Science 2016-04-15 Carlos Barrón-Romero

This paper draws on diverse areas of computer science to develop a unified view of computation: (1) Optimization in operations research, where a numerical objective function is maximized under constraints, is generalized from the numerical…

Artificial Intelligence · Computer Science 2013-02-11 A. Nait Abdallah , M. H. van Emden

Algorithms for learning the conditional probabilities of Bayesian networks with hidden variables typically operate within a high-dimensional search space and yield only locally optimal solutions. One way of limiting the search space and…

Artificial Intelligence · Computer Science 2013-01-18 Frank Wittig , Anthony Jameson

In most natural sciences there is currently the insight that it is necessary to bridge gaps between different processes which can be observed on different scales. This is especially true in the field of chemical reactions where the…

Molecular Networks · Quantitative Biology 2008-03-03 L. Sbano , M. Kirkilionis

Randomized algorithms are used in many state-of-the-art solvers for constraint satisfaction problems (CSP) and Boolean satisfiability (SAT) problems. For many of these problems, there is no single solver which will dominate others. Having…

Machine Learning · Computer Science 2021-06-25 Jake Tuero , Michael Buro

Boolean network models of strongly connected modules are capable of capturing the high regulatory complexity of many biological gene regulatory circuits. We study numerically the previously introduced basin entropy, a parameter for the…

Disordered Systems and Neural Networks · Physics 2009-11-13 P. Krawitz , I. Shmulevich

In this paper, we analyse large random Boolean networks in terms of a constraint satisfaction problem. We first develop an algorithmic scheme which allows to prune simple logical cascades and under-determined variables, returning thereby…

Statistical Mechanics · Physics 2009-11-11 L. Correale , M. Leone , A. Pagnani , M. Weigt , R. Zecchina

We introduce a graceful approach to probabilistic inference called bounded conditioning. Bounded conditioning monotonically refines the bounds on posterior probabilities in a belief network with computation, and converges on final…

Artificial Intelligence · Computer Science 2013-04-08 Eric J. Horvitz , Jaap Suermondt , Gregory F. Cooper

We exploit qualitative probabilistic relationships among variables for computing bounds of conditional probability distributions of interest in Bayesian networks. Using the signs of qualitative relationships, we can implement abstraction…

Artificial Intelligence · Computer Science 2013-02-01 Chao-Lin Liu , Michael P. Wellman

We are interested in assigning a pre-specified number of nodes as leaders in order to minimize the mean-square deviation from consensus in stochastically forced networks. This problem arises in several applications including control of…

Optimization and Control · Mathematics 2014-12-11 Fu Lin , Makan Fardad , Mihailo R. Jovanović

We consider the problem of searching for proofs in sequential presentations of logics with multiplicative (or intensional) connectives. Specifically, we start with the multiplicative fragment of linear logic and extend, on the one hand, to…

Logic in Computer Science · Computer Science 2007-05-23 James Harland , David Pym

In this work, several random Boolean networks (RBN) are generated and analyzed from two characteristics: their time evolution diagram and their transition diagram. For this purpose, its randomness is estimated using three measures, of which…

Information Theory · Computer Science 2024-09-04 Manuel de J. Luevano , Alejandro Puga

Quality control in industrial processes is increasingly making use of prior scientific knowledge, often encoded in physical models that require numerical approximation. Statistical prediction, and subsequent optimization, is key to ensuring…

Other Statistics · Statistics 2018-10-23 Antony Overstall , David Woods , Kieran Martin

Interacting biological systems at all organizational levels display emergent behavior. Modeling these systems is made challenging by the number and variety of biological components and interactions (from molecules in gene regulatory…

Molecular Networks · Quantitative Biology 2023-10-20 Jordan C. Rozum , Colin Campbell , Eli Newby , Fatemeh Sadat Fatemi Nasrollahi , Reka Albert