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Cancers are the leading cause of death in many countries. Early diagnosis plays a crucial role in having proper treatment for this debilitating disease. The automated classification of the type of cancer is a challenging task since…

Image and Video Processing · Electrical Eng. & Systems 2021-08-20 Hosein Barzekar , Zeyun Yu

Lung Cancer is the most common cause of cancer-related death worldwide. Early and automatic diagnosis of Solitary Pulmonary Nodules (SPN) in Computer Tomography (CT) chest scans can provide early treatment as well as doctor liberation from…

Image and Video Processing · Electrical Eng. & Systems 2020-03-31 Ioannis D. Apostolopoulos

The progression of lung cancer implies the intrinsic ordinal relationship of lung nodules at different stages-from benign to unsure then to malignant. This problem can be solved by ordinal regression methods, which is between classification…

Computer Vision and Pattern Recognition · Computer Science 2021-02-02 Yiming Lei , Hongming Shan , Junping Zhang

In cancer genomics, it is of great importance to distinguish driver mutations, which contribute to cancer progression, from causally neutral passenger mutations. We propose a random-effect regression approach to estimate the effects of…

Methodology · Statistics 2023-06-30 Kin Yau Wong , Donglin Zeng , D. Y. Lin

Early detection of breast cancer is a powerful tool towards decreasing its socioeconomic burden. Although, artificial intelligence (AI) methods have shown remarkable results towards this goal, their "black box" nature hinders their wide…

Machine Learning · Computer Science 2022-02-07 Panagiota Karatza , Kalliopi V. Dalakleidi , Maria Athanasiou , Konstantina S. Nikita

Cardiac diseases are among the leading causes of morbidity and mortality worldwide, which requires accurate and timely diagnostic strategies. In this study, we introduce an innovative approach that combines deep learning image registration…

Machine Learning · Computer Science 2025-07-09 Comte Valentin , Gemma Piella , Mario Ceresa , Miguel A. Gonzalez Ballester

Prognostication for lung cancer, a leading cause of mortality, remains a complex task, as it needs to quantify the associations of risk factors and health events spanning a patient's entire life. One challenge is that an individual's…

Machine Learning · Statistics 2025-08-28 Stephen Salerno , Yi Li

Accurate diagnosis of breast cancer in histopathology images is challenging due to the heterogeneity of cancer cell growth as well as of a variety of benign breast tissue proliferative lesions. In this paper, we propose a practical and…

Computer Vision and Pattern Recognition · Computer Science 2020-05-06 Xingyu Li , Marko Radulovic , Ksenija Kanjer , Konstantinos N. Plataniotis

The integration of multi-modal data, such as pathological images and genomic data, is essential for understanding cancer heterogeneity and complexity for personalized treatments, as well as for enhancing survival predictions. Despite the…

Quantitative Methods · Quantitative Biology 2023-01-09 Lin Qiu , Aminollah Khormali , Kai Liu

The early identification of malignant pulmonary nodules is critical for better lung cancer prognosis and less invasive chemo or radio therapies. Nodule malignancy assessment done by radiologists is extremely useful for planning a preventive…

Image and Video Processing · Electrical Eng. & Systems 2019-12-19 Ilaria Bonavita , Xavier Rafael-Palou , Mario Ceresa , Gemma Piella , Vicent Ribas , Miguel A. González Ballester

The need for more usable and explainable machine learning models in healthcare increases the importance of developing and utilizing causal discovery algorithms, which aim to discover causal relations by analyzing observational data.…

Machine Learning · Computer Science 2023-05-31 Mugariya Farooq , Shahad Hardan , Aigerim Zhumbhayeva , Yujia Zheng , Preslav Nakov , Kun Zhang

Breast cancer is one of the leading causes of death across the world in women. Early diagnosis of this type of cancer is critical for treatment and patient care. Computer-aided detection (CAD) systems using convolutional neural networks…

Image and Video Processing · Electrical Eng. & Systems 2019-09-27 Sara Hosseinzadeh Kassani , Peyman Hosseinzadeh Kassani , Michal J. Wesolowski , Kevin A. Schneider , Ralph Deters

Cancer is one of the most dangerous diseases to humans, and yet no permanent cure has been developed for it. Breast cancer is one of the most common cancer types. According to the National Breast Cancer foundation, in 2020 alone, more than…

Image and Video Processing · Electrical Eng. & Systems 2022-03-10 Ali Bou Nassif , Manar Abu Talib , Qassim Nasir , Yaman Afadar , Omar Elgendy

Diseases involve complex processes and modifications to the cellular machinery. The gene expression profile of the affected cells contains characteristic patterns linked to a disease. Hence, biological knowledge pertaining to a disease can…

Quantitative Methods · Quantitative Biology 2020-04-13 Thomas Gaudelet , Noel Malod-Dognin , Jon Sanchez-Valle , Vera Pancaldi , Alfonso Valencia , Natasa Przulj

This article represents one of the contemporary trends in the application of the latest methods of information and communication technology for medicine through an expert system helps the doctor to diagnose some chest diseases which is…

Artificial Intelligence · Computer Science 2018-02-21 Ismail Kayali

In 2020, prostate cancer saw a staggering 1.4 million new cases, resulting in over 375,000 deaths. The accurate identification of clinically significant prostate cancer is crucial for delivering effective treatment to patients.…

Image and Video Processing · Electrical Eng. & Systems 2024-05-14 Chi-en Amy Tai , Alexander Wong

Aim: This study investigates treatment response prediction to neoadjuvant chemotherapy (NACT) in breast cancer patients, using longitudinal contrast-enhanced magnetic resonance images (CE-MRI) and clinical data. The goal is to develop…

Image and Video Processing · Electrical Eng. & Systems 2025-12-22 Rahul Ravi , Ruizhe Li , Tarek Abdelfatah , Stephen Chan , Xin Chen

Disease-gene association through Genome-wide association study (GWAS) is an arduous task for researchers. Investigating single nucleotide polymorphisms (SNPs) that correlate with specific diseases needs statistical analysis of associations.…

Quantitative Methods · Quantitative Biology 2020-12-21 Sezin Kircali Ata , Min Wu , Yuan Fang , Le Ou-Yang , Chee Keong Kwoh , Xiao-Li Li

Breast cancer(BC) is a prevalent type of malignant tumor in women. Early diagnosis and treatment are vital for enhancing the patients' survival rate. Downsampling in deep networks may lead to loss of information, so for compensating the…

Computer Vision and Pattern Recognition · Computer Science 2024-01-05 Bo Yang , Hong Peng , Xiaohui Luo , Jun Wang

Lung cancer has a high rate of recurrence in early-stage patients. Predicting the post-surgical recurrence in lung cancer patients has traditionally been approached using single modality information of genomics or radiology images. We…

Image and Video Processing · Electrical Eng. & Systems 2020-02-07 Vaishnavi Subramanian , Minh N. Do , Tanveer Syeda-Mahmood
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