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This paper presents a diffusion based probabilistic interpretation of spectral clustering and dimensionality reduction algorithms that use the eigenvectors of the normalized graph Laplacian. Given the pairwise adjacency matrix of all…

Numerical Analysis · Mathematics 2007-05-23 Boaz Nadler , Stephane Lafon , Ronald R. Coifman , Ioannis G. Kevrekidis

We propose a novel method to embed a functional magnetic resonance imaging (fMRI) dataset in a low-dimensional space. The embedding optimally preserves the local functional coupling between fMRI time series and provides a low-dimensional…

Machine Learning · Statistics 2008-01-16 Xilin Shen , François G. Meyer

An active learning algorithm for the classification of high-dimensional images is proposed in which spatially-regularized nonlinear diffusion geometry is used to characterize cluster cores. The proposed method samples from estimated cluster…

Machine Learning · Computer Science 2019-11-07 James M. Murphy

Medical image segmentation demands an efficient and robust segmentation algorithm against noise. The conventional fuzzy c-means algorithm is an efficient clustering algorithm that is used in medical image segmentation. But FCM is highly…

Computer Vision and Pattern Recognition · Computer Science 2010-04-13 S. Zulaikha Beevi , M. Mohammed Sathik , K. Senthamaraikannan

Tractography fiber clustering using diffusion MRI (dMRI) is a crucial strategy for white matter (WM) parcellation. Current methods primarily use the geometric information of fibers (i.e., the spatial trajectories) to group similar fibers…

Image and Video Processing · Electrical Eng. & Systems 2024-12-17 Jin Wang , Bocheng Guo , Yijie Li , Junyi Wang , Yuqian Chen , Jarrett Rushmore , Nikos Makris , Yogesh Rathi , Lauren J O'Donnell , Fan Zhang

Diffusion magnetic resonance imaging offers unique in vivo sensitivity to tissue microstructure in brain white matter, which undergoes significant changes during development and is compromised in virtually every neurological disorder. Yet,…

Clustering algorithms partition a dataset into groups of similar points. The primary contribution of this article is the Multiscale Spatially-Regularized Diffusion Learning (M-SRDL) clustering algorithm, which uses spatially-regularized…

Machine Learning · Computer Science 2022-04-08 Sam L. Polk , James M. Murphy

The creation of fractal clusters by diffusion limited aggregation (DLA) is studied by using iterated stochastic conformal maps following the method proposed recently by Hastings and Levitov. The object of interest is the function…

Multi-subject functional magnetic resonance imaging (fMRI) data has been increasingly used to study the population-wide relationship between human brain activity and individual biological or behavioral traits. A common method is to regress…

Applications · Statistics 2015-09-15 Fan Li , Tingting Zhang , Quanli Wang , Marlen Z. Gonzalez , Erin L. Maresh , James A. Coan

Recently, fluorescence-based optical techniques have emerged as a powerful tool to probe information in the mammalian brain. However, tissue heterogeneities prevent clear imaging of deep neuron bodies due to light scattering. While several…

The use of brain images as markers for diseases or behavioral differences is challenged by the small effects size and the ensuing lack of power, an issue that has incited researchers to rely more systematically on large cohorts. Coupled…

Machine Learning · Statistics 2015-11-17 Bertrand Thirion , Andrés Hoyos-Idrobo , Jonas Kahn , Gael Varoquaux

Functional Magnetic Resonance Imaging (fMRI) is a primary modality for studying brain activity. Modeling spatial dependence of imaging data at different scales is one of the main challenges of contemporary neuroimaging, and it could allow…

Applications · Statistics 2016-06-16 Stefano Castruccio , Hernando Ombao , Marc G. Genton

Diffusion Tensor Imaging (DTI) is an effective tool for the analysis of structural brain connectivity in normal development and in a broad range of brain disorders. However efforts to derive inherent characteristics of structural brain…

Computational Engineering, Finance, and Science · Computer Science 2018-02-14 Yu Jin , Joseph F. JaJa , Rong Chen , Edward H. Herskovits

Functional data analysis deals with data recorded densely over time (or any other continuum) with one or more observed curves per subject. Conceptually, functional data are continuously defined, but in practice, they are usually observed at…

Methodology · Statistics 2023-01-20 Chengqian Xian , Camila de Souza , John Jewell , Ronaldo Dias

Standard fMRI connectivity analyses depend on aggregating the time series of individual voxels within regions of interest (ROIs). In certain cases, this spatial aggregation implies a loss of valuable functional and anatomical information…

Neurons and Cognition · Quantitative Biology 2019-08-12 Ruben Sanchez-Romero , Joseph D. Ramsey , Kun Zhang , Clark Glymour

Functional magnetic resonance imaging (fMRI) data contain complex spatiotemporal dynamics, thus researchers have developed approaches that reduce the dimensionality of the signal while extracting relevant and interpretable dynamics. Models…

Computer Vision and Pattern Recognition · Computer Science 2022-05-30 Eloy Geenjaar , Amrit Kashyap , Noah Lewis , Robyn Miller , Vince Calhoun

The high dimensionality of hyperspectral images often results in the degradation of clustering performance. Due to the powerful ability of deep feature extraction and non-linear feature representation, the clustering algorithm based on deep…

Machine Learning · Computer Science 2019-04-02 Jinguang Sun , Wanli Wang , Xian Wei , Li Fang , Xiaoliang Tang , Yusheng Xu , Hui Yu , Wei Yao

Spectral clustering and diffusion maps are celebrated dimensionality reduction algorithms built on eigen-elements related to the diffusive structure of the data. The core of these procedures is the approximation of a Laplacian through a…

Machine Learning · Statistics 2023-02-15 Loucas Pillaud-Vivien , Francis Bach

Information mapping is a popular application of Multivoxel Pattern Analysis (MVPA) to fMRI. Information maps are constructed using the so called searchlight method, where the spherical multivoxel neighborhood of every voxel (i.e., a…

Neurons and Cognition · Quantitative Biology 2012-10-24 Shivakumar Viswanathan , Matthew Cieslak , Scott T. Grafton

In several environmental applications data are functions of time, essentially con- tinuous, observed and recorded discretely, and spatially correlated. Most of the methods for analyzing such data are extensions of spatial statistical tools…

Methodology · Statistics 2011-06-28 Elvira Romano , Antonio Balzanella , Rosanna Verde