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When the motion of a motile cell is observed closely, it appears erratic, and yet the combination of nonequilibrium forces and surfaces can produce striking examples of organization in microbial systems. While most of our current…

We develop a numerical framework to simulate the locomotion of a flagellated bacterium with a spheroidal head (such as Escherichia coli) in biological fluids like mucus, which are entangled polymer solutions exhibiting elasto-viscoplastic…

Fluid Dynamics · Physics 2026-04-01 Arjun Sharma , Sabarish V. Narayanan , Sarah Hormozi , Donald L. Koch

How does a cell self-organize so that its appendages attain specific lengths that are convenient for their respective functions? What kind of 'rulers' does a cell use to measure the length of these appendages? How does a cell transport…

Biological Physics · Physics 2021-08-31 Swayamshree Patra , Debashish Chowdhury

An oscillating body floating at the water surface produces a wave-field of self-generated waves. When the oscillation induces a difference in fore-aft wave amplitude squared, these self-generated waves can be used as a mechanism to propel…

Fluid Dynamics · Physics 2025-06-16 D. O'Donovan , M. D. Bustamante , O. Devauchelle , G. P. Benham

The shear-induced deformation of a capsule with a stiff nucleus, a model of eukaryotic cells, is studied numerically. The membrane of the cell and of its nucleus are modelled as a thin and impermeable elastic material obeying a Neo-Hookean…

Fluid Dynamics · Physics 2017-05-29 Arash Alizad Banaei , Jean-Christophe Loiseau , Iman Lashgari , Luca Brandt

What is the optimal shape of a dendrite? Of course, optimality refers to some particular criterion. In this paper, we look at the case of a dendrite sealed at one end and connected at the other end to a soma. The electrical potential in the…

Analysis of PDEs · Mathematics 2008-11-04 Antoine Henrot , Yannick Privat

The optimal shapes attained by contractile cells on adhesive substrates are determined by the interplay between intracellular forces and adhesion with the extracellular matrix. We model the cell as a contractile film bounded by an elastic…

Biological Physics · Physics 2013-05-10 Shiladitya Banerjee , Luca Giomi

Ubiquitous in eukaryotic organisms, the flagellum is a well-studied organelle that is well-known to be responsible for motility in a variety of organisms. Commonly necessitated in their study is the capability to image and subsequently…

Quantitative Methods · Quantitative Biology 2019-03-22 Benjamin J. Walker , Kenta Ishimoto , Richard J. Wheeler

Adjoint-based shape optimization most often relies on Eulerian flow field formulations. However, since Lagrangian particle methods are the natural choice for solving sedimentation problems in oceanography, extensions to the Lagrangian…

Fluid Dynamics · Physics 2022-09-07 Luka Schlegel , Volker Schulz

A mechanism for self propulsion of deformable vesicle has been proposed, vesicle moves by sensing the self-generated chemical gradient. Like many molecular motors they suffer strong perturbations from the environment in which they move as a…

Biological Physics · Physics 2015-10-14 Shivam Gupta , Sreeja K. K. , Snigdha Thakur

The quest for the optimal navigation strategy in a complex environment is at the heart of microswimmer applications like cargo carriage or drug targeting to cancer cells. Here, we formulate a variational Fermat's principle for microswimmers…

Soft Condensed Matter · Physics 2019-01-25 Benno Liebchen , Hartmut Löwen

The quest for designing new self-propelled colloids is fuelled by the demand for simple experimental models to study the collective behaviour of their more complex natural counterparts. Most synthetic self-propelled particles move by…

Soft Condensed Matter · Physics 2017-09-21 Hanumantha Rao Vutukuri , Bram Bet , René van Roij , Marjolein Dijkstra , Wilhelm T. S. Huck

A fin-body configuration is tested in a water tunnel to study the hydrodynamic loads and vortex evolution under dynamic fin-flapping motions, which is an idealized approximation of the pectoral fins of fish. The fin flaps about its leading…

Fluid Dynamics · Physics 2026-04-24 Xiaowei He , Kenneth Breuer

Many swimming and flying animals are observed to cruise in a narrow range of Strouhal numbers, where the Strouhal number ${St = 2fA/U}$ is a dimensionless parameter that relates stroke frequency $f$, amplitude $A$, and forward speed $U$.…

Fluid Dynamics · Physics 2019-04-11 Daniel Floryan , Tyler Van Buren , Alexander J. Smits

Biologically inspired pressure actuated cellular structures can alter their shape through pressure variations. Previous work introduced a computational framework for pressure actuated cellular structures which was limited to two cell rows…

Quantitative Methods · Quantitative Biology 2017-04-10 Markus Pagitz , Remco I. Leine

Lipid vesicles appear ubiquitously in biological systems. Understanding how the mechanical and intermolecular interations deform vesicle membrane is a fundamental question in biophysics. In this article we developed a fast algorithm to…

Numerical Analysis · Mathematics 2014-11-17 Michael Mikucki , Y. C. Zhou

Biological microswimmers, like euglena, deform their body shape to swim through tight confinements having length scales comparable to the microswimmer length scale. Recently, it was shown that self-propelling active droplets can also…

Soft Condensed Matter · Physics 2024-07-08 Subhasish Guchhait , Smita Sontakke , Shubhadeep Mandal , Ranabir Dey

The passive rotation of rigid helical filaments is the propulsion strategy used by flagellated bacteria and some artificial microswimmers to navigate at low Reynolds numbers. In a classical 1976 paper, Lighthill calculated the `optimal'…

Fluid Dynamics · Physics 2025-03-27 Pyae Hein Htet , Eric Lauga

Flagella beating in complex fluids are significantly influenced by viscoelastic stresses. Relevant examples include the ciliary transport of respiratory airway mucus and the motion of spermatozoa in the mucus-filled female reproductive…

Soft Condensed Matter · Physics 2008-10-02 Eric Lauga

We present a model for unicellular algal growth as motivated by several experiments implicating the importance of calcium ions and ``loosening'' enzymes in morphogenesis. A growing cell at rest in a diffusive calcium solution is viewed as…

patt-sol · Physics 2009-10-30 Royce Kam , Herbert Levine
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