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Clustering methods are popular for revealing structure in data, particularly in the high-dimensional setting common to contemporary data science. A central statistical question is, "are the clusters really there?" One pioneering method in…

Methodology · Statistics 2023-08-28 Thomas H. Keefe , J. S. Marron

Cluster analysis has proved to be an invaluable tool for the exploratory and unsupervised analysis of high dimensional datasets. Among methods for clustering, hierarchical approaches have enjoyed substantial popularity in genomics and other…

Methodology · Statistics 2014-11-20 Patrick K. Kimes , Yufeng Liu , D. Neil Hayes , J. S. Marron

Although numerous algorithms have been proposed to solve the categorical data clustering problem, how to access the statistical significance of a set of categorical clusters remains unaddressed. To fulfill this void, we employ the…

Machine Learning · Computer Science 2022-11-09 Lianyu Hu , Mudi Jiang , Yan Liu , Zengyou He

Inference in clustering is paramount to uncovering inherent group structure in data. Clustering methods which assess statistical significance have recently drawn attention owing to their importance for the identification of patterns in high…

Methodology · Statistics 2021-06-18 Debora Zava Bello , Marcio Valk , Gabriela Bettella Cybis

Clustering methods are a valuable tool for the identification of patterns in high dimensional data with applications in many scientific problems. However, quantifying uncertainty in clustering is a challenging problem, particularly when…

Methodology · Statistics 2018-06-01 Marcio Valk , Gabriela Bettella Cybis

When scholars suspect units are dependent on each other within clusters but independent of each other across clusters, they employ cluster-robust standard errors (CRSEs). Nevertheless, what to cluster over is sometimes unknown. For…

Methodology · Statistics 2025-11-12 Kentaro Fukumoto

Cluster analysis is an unsupervised learning strategy that can be employed to identify subgroups of observations in data sets of unknown structure. This strategy is particularly useful for analyzing high-dimensional data such as microarray…

Methodology · Statistics 2016-10-07 Erika S. Helgeson , Eric Bair

High-dimensional clustering analysis is a challenging problem in statistics and machine learning, with broad applications such as the analysis of microarray data and RNA-seq data. In this paper, we propose a new clustering procedure called…

Methodology · Statistics 2022-10-31 Tianqi Liu , Yu Lu , Biqing Zhu , Hongyu Zhao

Cluster analysis is a fundamental research issue in statistics and machine learning. In many modern clustering methods, we need to determine whether two subsets of samples come from the same cluster. Since these subsets are usually…

Machine Learning · Computer Science 2025-07-15 Xinying Liu , Lianyu Hu , Mudi Jiang , Simeng Zhang , Jun Lou , Zengyou He

We consider clustering based on significance tests for Gaussian Mixture Models (GMMs). Our starting point is the SigClust method developed by Liu et al. (2008), which introduces a test based on the k-means objective (with k = 2) to decide…

Methodology · Statistics 2019-10-08 Purvasha Chakravarti , Sivaraman Balakrishnan , Larry Wasserman

While clustering is ubiquitously used across science and industry, uncertainty in cluster assignments is rarely quantified with rigorous guarantees. We propose a novel conformal inference framework for clustering that returns confidence…

Methodology · Statistics 2026-04-13 YoonHaeng Hur , Anirban Nath , Genevera Allen

Cluster analysis methods are used to identify homogeneous subgroups in a data set. In biomedical applications, one frequently applies cluster analysis in order to identify biologically interesting subgroups. In particular, one may wish to…

Methodology · Statistics 2016-09-23 Sheila Gaynor , Eric Bair

Spectral clustering is a powerful method for finding structure in a dataset through the eigenvectors of a similarity matrix. It often outperforms traditional clustering algorithms such as $k$-means when the structure of the individual…

Numerical Analysis · Mathematics 2019-04-26 Paola Favati , Grazia Lotti , Ornella Menchi , Francesco Romani

Unsupervised learning has gained prominence in the big data era, offering a means to extract valuable insights from unlabeled datasets. Deep clustering has emerged as an important unsupervised category, aiming to exploit the non-linear…

Machine Learning · Computer Science 2024-02-02 Georgios Vardakas , Ioannis Papakostas , Aristidis Likas

Clustering is an essential data mining tool that aims to discover inherent cluster structure in data. For most applications, applying clustering is only appropriate when cluster structure is present. As such, the study of clusterability,…

Machine Learning · Statistics 2018-10-30 A. Adolfsson , M. Ackerman , N. C. Brownstein

Clustering is a central tool in biomedical research for discovering heterogeneous patient subpopulations, where group boundaries are often diffuse rather than sharply separated. Traditional methods produce hard partitions, whereas soft…

Methodology · Statistics 2026-01-07 Qiuyi Wu , Zihan Zhu , Anru R. Zhang

Spectral clustering refers to a family of unsupervised learning algorithms that compute a spectral embedding of the original data based on the eigenvectors of a similarity graph. This non-linear transformation of the data is both the key of…

Machine Learning · Computer Science 2019-01-30 Nicolas Tremblay , Andreas Loukas

Data-based classification is fundamental to most branches of science. While recent years have brought enormous progress in various areas of statistical computing and clustering, some general challenges in clustering remain: model selection,…

Artificial Intelligence · Computer Science 2007-06-13 Jens Oehlschlägel

Unsupervised clustering algorithms for vectors has been widely used in the area of machine learning. Many applications, including the biological data we studied in this paper, contain some boundary datapoints which show combination…

Machine Learning · Computer Science 2022-05-23 Yingcong Li , Chandra Sekhar Mukherjee , Jiapeng Zhang

With rapidly increasing data, clustering algorithms are important tools for data analytics in modern research. They have been successfully applied to a wide range of domains; for instance, bioinformatics, speech recognition, and financial…

Data Structures and Algorithms · Computer Science 2015-12-01 Ka-Chun Wong
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