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We review and introduce a generalized reaction-diffusion approach to epidemic spreading in a metapopulation modeled as a complex network. The metapopulation consists of susceptible and infected individuals that are grouped in subpopulations…

Physics and Society · Physics 2015-06-12 Halvor Lund , Ludvig Lizana , Ingve Simonsen

Dynamical reaction-diffusion processes and meta-population models are standard modeling approaches for a wide variety of phenomena in which local quantities - such as density, potential and particles - diffuse and interact according to the…

Statistical Mechanics · Physics 2007-05-23 V. Colizza , R. Pastor-Satorras , A. Vespignani

We study a simple reaction-diffusion population model [proposed by A. Windus and H. J. Jensen, J. Phys. A: Math. Theor. 40, 2287 (2007)] on scale-free networks. In the case of fully random diffusion, the network topology cannot affect the…

Physics and Society · Physics 2009-11-13 An-Cai Wu , Xin-Jian Xu , J. F. F. Mendes , Ying-Hai Wang

We present new empirical evidence, based on millions of interactions on Twitter, confirming that human contacts scale with population sizes. We integrate such observations into a reaction-diffusion metapopulation framework providing an…

Physics and Society · Physics 2014-11-27 Michele Tizzoni , Kaiyuan Sun , Diego Benusiglio , Márton Karsai , Nicola Perra

This is a brief "proof of concept" article that shows nonlocal diffusion is well suited to the study of pattern formation and the particular application of public sentiment. We use a nonlocal reaction-diffusion equation to model the…

Analysis of PDEs · Mathematics 2022-10-28 Joseph L. Shomberg

Computational models of infectious disease can be broadly categorized into two types: individual-based (Agent-based), or compartmental models. While compartmental models can be structured to separate distinct sectors of a population, they…

Populations and Evolution · Quantitative Biology 2021-12-14 Cameron Zachreson , Sheryl Chang , Nathan Harding , Mikhail Prokopenko

The presence of one or more species at some spatial locations but not others is a central matter in ecology. This phenomenon is related to ecological pattern formation. Nonlocal interactions can be considered as one of the mechanisms…

Populations and Evolution · Quantitative Biology 2017-12-29 Ozgur Aydogmus

Capturing the structured mixing within a population is key to the reliable projection of infectious disease dynamics and hence informed control. Both heterogeneity in the number of contacts and age-structured mixing have been repeatedly…

Social and Information Networks · Computer Science 2026-03-17 Luke Murray Kearney , Emma L Davis , Matt J Keeling

Ideas, behaviors, and opinions spread through social networks. If the probability of spreading to a new individual is a non-linear function of the fraction of the individuals' affected neighbors, such a spreading process becomes a "complex…

Physics and Society · Physics 2023-08-30 Julian Kates-Harbeck , Michael M. Desai

The spatial structure of populations is a key element in the understanding of the large scale spreading of epidemics. Motivated by the recent empirical evidence on the heterogeneous properties of transportation and commuting patterns among…

Populations and Evolution · Quantitative Biology 2008-03-19 Vittoria Colizza , Alessandro Vespignani

We consider a reaction-diffusion model for a population structured in phenotype. We assume that the population lives in a heterogeneous periodic environment, so that a given phenotypic trait may be more or less fit according to the spatial…

Analysis of PDEs · Mathematics 2025-03-07 Nathanaël Boutillon , Luca Rossi

In this paper we analyse a class of nonlinear cross-diffusion systems for two species with local repulsive interactions that exhibit a formal gradient flow structure with respect to the Wasserstein metric. We show that systems where the…

Analysis of PDEs · Mathematics 2019-06-11 M. Burger , J. A. Carrillo , J. -F. Pietschmann , M. Schmidtchen

I study the spreading of infectious diseases on heterogeneous populations. I represent the population structure by a contact-graph where vertices represent agents and edges represent disease transmission channels among them. The population…

Populations and Evolution · Quantitative Biology 2009-11-13 Alexei Vazquez

Capturing the structure of a population and characterising contacts within the population are key to reliable projections of infectious disease. Two main elements of population structure -- contact heterogeneity and age -- have been…

Physics and Society · Physics 2025-03-17 Luke Murray Kearney , Emma L. Davis , Matt J. Keeling

In this paper, we consider reaction-diffusion epidemic models with mass action or standard incidence mechanism and study the impact of limiting population movement on disease transmissions. We set either the dispersal rate of the…

Analysis of PDEs · Mathematics 2023-12-19 Rachidi Salako , Yixiang Wu

A large variety of real systems are composed by entities in relationships which can be represented by networks. In many of these systems, elements are embedded in the space and location information impacts properties and evolution. Local…

Physics and Society · Physics 2021-11-09 Michele Tirico , Stefan Balev , Antoine Dutot , Damien Olivier

Individuals are always limited by some inelastic resources, such as time and energy, which restrict them to dedicate to social interaction and limit their contact capacity. Contact capacity plays an important role in dynamics of social…

Physics and Society · Physics 2015-12-25 Wei Wang , Panpan Shu , Yu-Xiao Zhu , Ming Tang , Yi-Cheng Zhang

Individual contributions to the spread of an epidemic vary widely due to an individual's location in a social network and their intrinsic ability to spread or contract diseases. While the effect of heterogeneous population structure and…

Populations and Evolution · Quantitative Biology 2026-05-14 Abhay Gupta , Nicholas W. Landry

Many epidemic processes in networks spread by stochastic contacts among their connected vertices. There are two limiting cases widely analyzed in the physics literature, the so-called contact process (CP) where the contagion is expanded at…

Computational Physics · Physics 2010-02-19 S. Gomez , A. Arenas , J. Borge-Holthoefer , S. Meloni , Y. Moreno

The contact structure of the population shapes the progression of epidemics. Nonetheless, the joint evolution of individual behavioral adaptations and disease dynamics on networks remains poorly understood. We use a…

Physics and Society · Physics 2025-08-27 Baltazar Espinoza , Jimmy Calvo-Monge , Fabio Sanchez , Simon A. Levin , Madhav Marathe
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