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The fields of computing and biology have begun to cross paths in new ways. In this paper a review of the current research in biological computing is presented. Fundamental concepts are introduced and these foundational elements are explored…

Computational Engineering, Finance, and Science · Computer Science 2009-11-10 Balaji Akula , James Cusick

Today's distributed and pervasive computing addresses large-scale cyber-physical ecosystems, characterised by dense and large networks of devices capable of computation, communication and interaction with the environment and people. While…

The drive for reproducibility in the computational sciences has provoked discussion and effort across a broad range of perspectives: technological, legislative/policy, education, and publishing. Discussion on these topics is not new, but…

Quantitative Methods · Quantitative Biology 2018-10-10 Daniel G. Hurley , Joseph Cursons , Matthew Faria , David M. Budden , Vijay Rajagopal , Edmund J. Crampin

In the era of big data, transformation of biomedical big data into valuable knowledge has been one of the most important challenges in bioinformatics. Deep learning has advanced rapidly since the early 2000s and now demonstrates…

Machine Learning · Computer Science 2016-06-21 Seonwoo Min , Byunghan Lee , Sungroh Yoon

Motivation: The rapid growth of biological data has intensified the need for transparent, reproducible, and well-documented computational workflows. The ability to clearly connect the steps of a workflow in the code with their description…

Computation and Language · Computer Science 2026-03-10 Clémence Sebe , Olivier Ferret , Aurélie Névéol , Mahdi Esmailoghli , Ulf Leser , Sarah Cohen-Boulakia

The main goal of this paper is to define a collaborative innovation process as well as a supporting tool. It is motivated through the increasing competition on global markets and the resultant propagation of decentralized projects with a…

Computers and Society · Computer Science 2019-05-08 Matthias Joiko , Florian Kohnen , Kevin Lapinski , Houda Moudrik , Irawan Nurhas , Florian Paproth , Jan M. Pawlowski

Open source bioinformatics tools running under MS Windows are rare to find, and those running under Windows HPC cluster are almost non-existing. This is despite the fact that the Windows is the most popular operating system used among life…

Mathematical Software · Computer Science 2009-05-06 Mohamed Abouelhoda , Hisham Mohamed

Bioinformatics is a new discipline that addresses the need to manage and interpret the data that in the past decade was massively generated by genomic research. This discipline represents the convergence of genomics, biotechnology and…

Computational Engineering, Finance, and Science · Computer Science 2009-11-24 Sabu M. Thampi

The web ecosystem is rapidly evolving with changing business and functional models. Cloud platforms are available in a SaaS, PaaS and IaaS model designed around commoditized Linux based servers. 10 billion users will be online and accessing…

Software Engineering · Computer Science 2018-09-24 Shaun C. D'Souza

It is popular nowadays to bring techniques from bibliometrics and scientometrics into the world of digital libraries to analyze the collaboration patterns and explore mechanisms which underlie community development. In this paper we use the…

Digital Libraries · Computer Science 2010-12-27 Maria Biryukov , Cailing Dong

Over the last decade, the cloud computing landscape has transformed from a centralised architecture made of large data centres to a distributed and heterogeneous architecture embracing edge and IoT units. This shift has created the…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-06-28 Jämes Ménétrey , Marcelo Pasin , Pascal Felber , Valerio Schiavoni

The applicability of computational models to the biological world is an active topic of debate. We argue that a useful path forward results from abandoning hard boundaries between categories and adopting an observer-dependent, pragmatic…

Multiagent Systems · Computer Science 2022-12-22 Joshua Bongard , Michael Levin

The rapid growth of scientific software has created practical barriers for bioinformatics research. Although powerful statistical, artificial intelligence (AI)-based methods are now widely available, their effective use is often hindered by…

Software Engineering · Computer Science 2026-04-24 Simon Süwer , Zoe Chervontseva , Kester Bagemihl , Jan Baumbach , Olga Tsoy , Andreas Maier

Background, enhancing interoperability of bioinformatics knowledge bases is a high priority requirement to maximize data reusability, and thus increase their utility such as the return on investment for biomedical research. A knowledge base…

Databases · Computer Science 2023-07-06 Tarcisio Mendes de Farias , Julien Wollbrett , Marc Robinson-Rechavi , Frederic Bastian

Large Language Models (LLMs) and LLM-based agents show great promise in accelerating scientific research. Existing benchmarks for measuring this potential and guiding future development continue to evolve from pure recall and rote knowledge…

"Volunteer computing" is the use of consumer digital devices for high-throughput scientific computing. It can provide large computing capacity at low cost, but presents challenges due to device heterogeneity, unreliability, and churn.…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-03-06 David P. Anderson

Biologically inspired computing is an area of computer science which uses the advantageous properties of biological systems. It is the amalgamation of computational intelligence and collective intelligence. Biologically inspired mechanisms…

Neural and Evolutionary Computing · Computer Science 2009-10-22 Sabu M. Thampi

User experience (UX) has undergone a revolution in collaborative practices, due to tools that enable quick feedback and continuous collaboration with a varied team across a design's lifecycle. However, it is unclear how this shift in…

Human-Computer Interaction · Computer Science 2023-02-28 K. J. Kevin Feng , Tony W. Li , Amy X. Zhang

Open-source software is increasingly reused, complicating the process of patching to repair bugs. In the case of Linux, a distinct ecosystem has formed, with Linux mainline serving as the upstream, stable or long-term-support (LTS) systems…

Software Engineering · Computer Science 2024-02-09 Xingyu Li , Zheng Zhang , Zhiyun Qian , Trent Jaeger , Chengyu Song

Real-time operating systems employ spatial and temporal isolation to guarantee predictability and schedulability of real-time systems on multi-core processors. Any unbounded and uncontrolled cross-core performance interference poses a…

Operating Systems · Computer Science 2024-12-25 Zhaomeng Deng , Ziqi Zhang , Ding Li , Yao Guo , Yunfeng Ye , Yuxin Ren , Ning Jia , Xinwei Hu