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We introduce a new survival tree method for censored failure time data that incorporates three key advancements over traditional approaches. First, we develop a more computationally efficient splitting procedure that effectively mitigates…

Methodology · Statistics 2025-09-24 Ruiwen Zhou , Ke Xie , Lei Liu , Zhichen Xu , Jimin Ding , Xiaogang Su

A filament consists of local maximizers of a smooth function $f$ when moving in a certain direction. A filamentary structure is an important feature of the shape of an object and is also considered as an important lower dimensional…

Statistics Theory · Mathematics 2020-03-26 Wei Li , Subhashis Ghosal

The Bayesian method is noted to produce spuriously high posterior probabilities for phylogenetic trees in analysis of large datasets, but the precise reasons for this over-confidence are unknown. In general, the performance of Bayesian…

Statistics Theory · Mathematics 2018-10-15 Ziheng Yang , Tianqi Zhu

Approximate Bayesian computation (ABC) methods provide an elaborate approach to Bayesian inference on complex models, including model choice. Both theoretical arguments and simulation experiments indicate, however, that model posterior…

Constraints are a natural choice for prior information in Bayesian inference. In various applications, the parameters of interest lie on the boundary of the constraint set. In this paper, we use a method that implicitly defines a…

Statistics Theory · Mathematics 2022-09-27 Jasper Marijn Everink , Yiqiu Dong , Martin Skovgaard Andersen

We propose a Bayesian approach, called the posterior spectral embedding, for estimating the latent positions in random dot product graphs, and prove its optimality. Unlike the classical spectral-based adjacency/Laplacian spectral embedding,…

Statistics Theory · Mathematics 2019-04-30 Fangzheng Xie , Yanxun Xu

We present TreeClone, a latent feature allocation model to reconstruct tumor subclones subject to phylogenetic evolution that mimics tumor evolution. Similar to most current methods, we consider data from next-generation sequencing of tumor…

Applications · Statistics 2017-10-26 Tianjian Zhou , Subhajit Sengupta , Peter Mueller , Yuan Ji

It was recently observed by de Vienne et al. that a simple square root transformation of distances between taxa on a phylogenetic tree allowed for an embedding of the taxa into Euclidean space. While the justification for this was based on…

Populations and Evolution · Quantitative Biology 2016-05-04 Mark Layer , John A. Rhodes

This work considers the problem of learning the structure of multivariate linear tree models, which include a variety of directed tree graphical models with continuous, discrete, and mixed latent variables such as linear-Gaussian models,…

Machine Learning · Computer Science 2011-11-09 Animashree Anandkumar , Kamalika Chaudhuri , Daniel Hsu , Sham M. Kakade , Le Song , Tong Zhang

A phylogenetic tree is a way to organize a finite set of species, individuals or other sources of related data. The species for which we have existing DNA data make up the set of leaves of the tree. The balanced minimal evolution method of…

Combinatorics · Mathematics 2016-08-05 Stefan Forcey , Logan Keefe , William Sands

In this paper, we analyze posterior consistency of a Bayesian data assimilation problem under discretization. We prove convergence rates for the discrete posterior to ground truth solution under both conforming discretization and finite…

Numerical Analysis · Mathematics 2025-06-18 Erik Burman , Mingfei Lu

Bayesian analyses combine information represented by different terms in a joint Bayesian model. When one or more of the terms is misspecified, it can be helpful to restrict the use of information from suspect model components to modify…

Methodology · Statistics 2022-06-27 Xuejun Yu , David J. Nott , Michael Stanley Smith

Evolutionary relationships between species are represented by phylogenetic trees, but these relationships are subject to uncertainty due to the random nature of evolution. A geometry for the space of phylogenetic trees is necessary in order…

Statistics Theory · Mathematics 2022-09-21 Jonas Lueg , Maryam K. Garba , Tom M. W. Nye , Stephan F. Huckemann

We study distorted metrics on binary trees in the context of phylogenetic reconstruction. Given a binary tree $T$ on $n$ leaves with a path metric $d$, consider the pairwise distances $\{d(u,v)\}$ between leaves. It is well known that these…

Combinatorics · Mathematics 2007-05-23 Elchanan Mossel

The block bootstrap approximates sampling distributions from dependent data by resampling data blocks. A fundamental problem is establishing its consistency for the distribution of a sample mean, as a prototypical statistic. We use a…

Statistics Theory · Mathematics 2017-06-23 Johannes Tewes , Daniel J. Nordman , Dimitris N. Politis

Tree ensembles are flexible predictive models that can capture relevant variables and to some extent their interactions in a compact and interpretable manner. Most algorithms for obtaining tree ensembles are based on versions of boosting or…

Machine Learning · Statistics 2020-02-21 Gitesh Dawer , Yangzi Guo , Adrian Barbu

We study the rates of convergence of the posterior distribution for Bayesian density estimation with Dirichlet mixtures of normal distributions as the prior. The true density is assumed to be twice continuously differentiable. The bandwidth…

Statistics Theory · Mathematics 2009-09-29 Subhashis Ghosal , Aad van der Vaart

Recent interest in treespaces as well-founded mathematical domains for phylogenetic inference and statistical analysis for populations of anatomical trees has motivated research into efficient and rigorous methods for optimization problems…

Optimization and Control · Mathematics 2017-08-17 Sean Skwerer , Scott Provan , J. S. Marron

Phylogenetic trees are hybrid objects: branch lengths vary continuously, while topologies change discretely through edge contractions and expansions. Billera-Holmes-Vogtmann (BHV) tree space provides a canonical geometry for this structure,…

Populations and Evolution · Quantitative Biology 2026-05-22 Yasha Ektefaie , Leo Cui , Shrey Jain , Marinka Zitnik , Pardis Sabeti

A recurring theme in the least squares approach to phylogenetics has been the discovery of elegant combinatorial formulas for the least squares estimates of edge lengths. These formulas have proved useful for the development of efficient…

Combinatorics · Mathematics 2009-11-13 Radu Mihaescu , Lior Pachter
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