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Despite the common usage of a canonical, data-independent, hemodynamic response function (HRF), it is known that the shape of the HRF varies across brain regions and subjects. This suggests that a data-driven estimation of this function…

Computational Engineering, Finance, and Science · Computer Science 2014-11-10 Fabian Pedregosa , Michael Eickenberg , Philippe Ciuciu , Bertrand Thirion , Alexandre Gramfort

We present a non-parametric joint estimation method for fMRI task activation values and the hemodynamic response function (HRF). The HRF is modeled as a Gaussian process, making continuous evaluation possible for jittered paradigms and…

Applications · Statistics 2017-09-01 Michael Eickenberg , Aina Frau-Pascual , Andrés Hoyos-Idrobo

When working with task-related fMRI data, one of the most crucial parts of the data analysis consists of determining a proper estimate of the BOLD response. The following document presents a lite model for the Hemodynamic Response Function…

Neurons and Cognition · Quantitative Biology 2020-04-29 Manuel Morante

Standard detection of evoked brain activity in functional MRI (fMRI) relies on a fixed and known shape of the impulse response of the neurovascular coupling, namely the hemodynamic response function (HRF). To cope with this issue, the joint…

Applications · Statistics 2015-01-07 Aina Frau-Pascual , Thomas Vincent , Florence Forbes , Philippe Ciuciu

In this paper we introduce a new hierarchical model for the simultaneous detection of brain activation and estimation of the shape of the hemodynamic response in multi-subject fMRI studies. The proposed approach circumvents a major…

Applications · Statistics 2015-11-13 David Degras , Martin A. Lindquist

In the event-related functional magnetic resonance imaging (fMRI) data analysis, there is an extensive interest in accurately and robustly estimating the hemodynamic response function (HRF) and its associated statistics (e.g., the magnitude…

Applications · Statistics 2013-12-23 Jiaping Wang , Hongtu Zhu , Jianqing Fan , Kelly Giovanello , Weili Lin

In the current paper, we introduce a parametric data-driven model for functional near-infrared spectroscopy that decomposes a signal into a series of independent, rescaled, time-shifted, hemodynamic basis functions. Each decomposed waveform…

Signal Processing · Electrical Eng. & Systems 2020-01-24 Marco A. Pinto-Orellana , Diego C. Nascimento , Peyman Mirtaheri , Rune Jonassen , Anis Yazidi , Hugo L. Hammer

Inferring the functional specificity of brain regions from functional Magnetic Resonance Images (fMRI) data is a challenging statistical problem. While the General Linear Model (GLM) remains the standard approach for brain mapping,…

Machine Learning · Computer Science 2012-07-17 Fabian Pedregosa , Alexandre Gramfort , Gaël Varoquaux , Bertrand Thirion , Christophe Pallier , Elodie Cauvet

Neuronal brain activity in response to repeated stimuli can be perceived using functional magnetic resonance imaging (fMRI). In this paper, we develop a statistical model for fMRI data that estimates both the associated haemodynamic…

Applications · Statistics 2015-01-26 Christopher J. Brignell , William J. Browne , Ian L. Dryden , Susan T. Francis

Functional magnetic resonance imaging (fMRI) aims to locate activated regions in human brains when specific tasks are performed. The conventional tool for analyzing fMRI data applies some variant of the linear model, which is restrictive in…

Statistics Theory · Mathematics 2008-08-08 Chunming Zhang , Tao Yu

Previous studies on event-related functional magnetic resonance imaging experimental designs are primarily based on linear models, in which a known shape of the hemodynamic response function (HRF) is assumed. However, the HRF shape is…

Applications · Statistics 2014-01-09 Ming-Hung Kao , Dibyen Majumdar , Abhyuday Mandal , John Stufken

There remains an open question about the usefulness and the interpretation of Machine learning (MLE) approaches for discrimination of spatial patterns of brain images between samples or activation states. In the last few decades, these…

Machine Learning · Statistics 2022-09-22 JM Gorriz , R. Martin-Clemente , C. G. Puntonet , A. Ortiz , J. Ramirez , J. Suckling

Functional magnetic resonance imaging (fMRI) provides an indirect measurement of neuronal activity via hemodynamic responses that vary across brain regions and individuals. Ignoring this hemodynamic variability can bias downstream…

Image and Video Processing · Electrical Eng. & Systems 2026-01-26 William Consagra , Eardi Lila

Functional magnetic resonance imaging (fMRI) is one of the most popular methods for studying the human brain. Task-related fMRI data processing aims to determine which brain areas are activated when a specific task is performed and is…

Signal Processing · Electrical Eng. & Systems 2022-10-18 Paris A. Karakasis , Athanasios P. Liavas , Nicholas D. Sidiropoulos , Panagiotis G. Simos , Efrosini Papadaki

Neuroscience theory posits that the brain's visual system coarsely identifies broad object categories via neural activation patterns, with similar objects producing similar neural responses. Artificial neural networks also have internal…

Computer Vision and Pattern Recognition · Computer Science 2018-11-28 Nathaniel Blanchard , Jeffery Kinnison , Brandon RichardWebster , Pouya Bashivan , Walter J. Scheirer

Contemporary neuroscience has embraced network science to study the complex and self-organized structure of the human brain; one of the main outstanding issues is that of inferring from measure data, chiefly functional Magnetic Resonance…

Optimization and Control · Mathematics 2017-03-31 Giulia Prando , Mattia Zorzi , Alessandra Bertoldo , Alessandro Chiuso

Typical fMRI studies have focused on either the mean trend in the blood-oxygen-level-dependent (BOLD) time course or functional connectivity (FC). However, other statistics of the neuroimaging data may contain important information. Despite…

Neurons and Cognition · Quantitative Biology 2018-08-08 Garren Gaut , Xiangrui Li , Zhong-Lin Lu , Mark Steyvers

In standard clinical within-subject analyses of event-related fMRI data, two steps are usually performed separately: detection of brain activity and estimation of the hemodynamic response. Because these two steps are inherently linked, we…

Applications · Statistics 2012-02-08 Lotfi Chaari , Thomas Vincent , Florence Forbes , Michel Dojat , Philippe Ciuciu

Functional magnetic resonance imaging (fMRI) technology is popularly used in many fields for studying how the brain reacts to mental stimuli. The identification of optimal fMRI experimental designs is crucial for rendering precise…

Statistics Theory · Mathematics 2015-10-30 Ching-Shui Cheng , Ming-Hung Kao

This article introduces an R package to perform statistical analysis for task-based fMRI data at both individual and group levels. The analysis to detect brain activation at the individual level is based on modeling the fMRI signal using…

Applications · Statistics 2021-11-03 Johnatan Cardona Jiménez
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