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Hypothesis:Diffusion in confinement is an important fundamental problem with significant implications for applications of supported liquid phases. However, resolving the spatially dependent diffusion coefficient, parallel and perpendicular…

When an ionic liquid adsorbs onto a porous electrode, its ionic arrangement is deeply modified due to a screening of the Coulombic interactions by the metallic surface and by the confinement imposed upon it by the electrode's morphology. In…

The field of nanofluidics has shown considerable progress over the past decade thanks to key instrumental advances, leading to the discovery of a number of exotic transport phenomena for fluids and ions under extreme confinement. Recently,…

Chemical reactions inside cells are typically subject to the effects both of the cell's confining surfaces and of the viscoelastic behavior of its contents. In this paper, we show how the outcome of one particular reaction of relevance to…

Soft Condensed Matter · Physics 2015-06-04 Pinaki Bhattacharyya , Rati Sharma , Binny J. Cherayil

Molecular dynamics (MD) simulations were performed to investigate the influence of mechanical strain on irradiation-induced defect and dislocation evolution in nickel single crystals subjected to cumulative overlapping 5 keV collision…

We study the effect of spatial confinement on the strength of propulsive diffusiophoretic forces acting on a particle that generates density gradients by exploiting the chemical free energy of its environment. Using a recently proposed…

Statistical Mechanics · Physics 2007-09-17 M. N. Popescu , S. Dietrich , G. Oshanin

The folding of RNA and DNA strands plays crucial roles in biological systems and bionanotechnology. However, studying these processes with high-resolution numerical models is beyond current computational capabilities due to the timescales…

Soft Condensed Matter · Physics 2024-02-07 F. Tosti Guerra , E. Poppleton , P. Šulc , L. Rovigatti

The percentage and sequence of AT and GC base pairs and charges on the DNA backbone contribute significantly to the stiffness of DNA. This elastic property of DNA also changes with small interacting ligands. The single-molecule force…

Soft Condensed Matter · Physics 2017-02-02 Anurag Singh , Amar Nath Gupta

Nano-clustering occurs in the monophasic "pre-Ouzo" region of ternary liquid mixtures without the use of surfactants. This study is proposed to elucidate the nucleation and stability of multiscale nanodomains in a surfactant-free…

Chemical Physics · Physics 2025-05-21 Yawen Gao , Changsheng Chen , Mingbo Li , Chao Sun

We study the electron dynamics at a monocrystalline Pd(111) surface with stepped vicinal nanostructures modeled in a simple Kronig-Penney scheme. The unoccupied bands of the surface are resonantly excited \textit{via} the resonant charge…

Atomic Physics · Physics 2021-06-08 John Shaw , David Monismith , Yixao Zhang , Yixao Zhang , Himadri S. Chakraborty

Many studies have revealed that confined water chain flipping is closely related to the spatial size and even quantum effects of the confinement environment. Here, we show that these are not the only factors that affect the flipping process…

Biological Physics · Physics 2021-07-07 Le Jin , Xinrui Yang , Yu Zhu , Zhiyuan Zhang , Rui Liu , Zhigang Wang

The growing significance of RNA engineering in diverse biological applications has spurred interest in developing AI methods for structure-based RNA design. While diffusion models have excelled in protein design, adapting them for RNA…

Biomolecules · Quantitative Biology 2024-06-11 Divya Nori , Wengong Jin

Recent biological experiments have shown that certain types of cells are able to move in structured and confined environment even without the activation of focal adhesion. Focusing on this particular phenomenon and based on previous works,…

Analysis of PDEs · Mathematics 2022-12-05 Chiara Giverso , Gaspard Jankowiak , Luigi Preziosi , Christian Schmeiser

Co-optimizing mRNA sequences for both codon optimality and secondary structure is crucial for producing stable and efficacious mRNA therapeutics. Codon optimization, which adjusts nucleotide sequences to enhance translational efficiency,…

Molecular clouds interacting with supernova remnants may be subject to a greatly enhanced irradiation by cosmic rays produced at the shocked interface between the ejecta and the molecular gas. Over the past decade, broad-band observations…

Astrophysics · Physics 2009-11-11 M. Fatuzzo , F. C. Adams , F. Melia

We introduce model folding, a novel data-free model compression technique that merges structurally similar neurons across layers, significantly reducing the model size without the need for fine-tuning or access to training data. Unlike…

Machine Learning · Computer Science 2025-08-13 Dong Wang , Haris Šikić , Lothar Thiele , Olga Saukh

We present two methods for characterization of motional-mode configurations that are generally applicable to the weak and strong-binding limit of single or multiple trapped atomic ions. Our methods are essential to realize control of the…

It has been shown that minimum free energy structure for RNAs and RNA-RNA interaction is often incorrect due to inaccuracies in the energy parameters and inherent limitations of the energy model. In contrast, ensemble based quantities such…

Biomolecules · Quantitative Biology 2013-01-09 Hamidreza Chitsaz , Elmirasadat Forouzmand , Gholamreza Haffari

Using both theoretical modeling and computer simulations we study a model system for DNA interactions in the vicinity of charged membranes. We focus on the polarization of the mobile charges in the membranes due to the nearby charged rods…

Soft Condensed Matter · Physics 2009-10-31 Rebecca Menes , Niels Gronbech Jensen , Phil A. Pincus

We study how confining the equilibrium hard-sphere fluid to restrictive one- and two-dimensional channels with smooth interacting walls modifies its structure, dynamics, and entropy using molecular dynamics and transition-matrix Monte Carlo…

Statistical Mechanics · Physics 2007-05-23 Jeetain Mittal , Jeffrey R. Errington , Thomas M. Truskett
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