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Finding an Approximate Longest Common Substring (ALCS) within a given set $S=\{s_1,s_2,\ldots,s_m\}$ of $m \ge 2$ strings is a key problem in computational biology, such as identifying related mutations across multiple genetic sequences. We…

Data Structures and Algorithms · Computer Science 2025-09-22 Hamed Hasibi , Neerja Mhaskar , W. F. Smyth

Transformer models trained on long sequences often achieve higher accuracy than short sequences. Unfortunately, conventional transformers struggle with long sequence training due to the overwhelming computation and memory requirements.…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-11-09 Xiao Wang , Isaac Lyngaas , Aristeidis Tsaris , Peng Chen , Sajal Dash , Mayanka Chandra Shekar , Tao Luo , Hong-Jun Yoon , Mohamed Wahib , John Gouley

This study proposes a data condensation method for multivariate kernel density estimation by genetic algorithm. First, our proposed algorithm generates multiple subsamples of a given size with replacement from the original sample. The…

Methodology · Statistics 2022-03-04 Kiheiji Nishida

Deep convolutional neural networks (CNNs) with strong expressive ability have achieved impressive performances on single image super-resolution (SISR). However, their excessive amounts of convolutions and parameters usually consume high…

Image and Video Processing · Electrical Eng. & Systems 2020-07-22 Chunwei Tian , Ruibin Zhuge , Zhihao Wu , Yong Xu , Wangmeng Zuo , Chen Chen , Chia-Wen Lin

De novo assembly enables investigations of unknown genomes, paving the way for personalized medicine and disease management. However, it faces immense computational challenges arising from the excessive data volumes and algorithmic…

Hardware Architecture · Computer Science 2025-05-14 Heewoo Kim , Sanjay Sri Vallabh Singapuram , Haojie Ye , Joseph Izraelevitz , Trevor Mudge , Ronald Dreslinski , Nishil Talati

DNA Data storage has recently attracted much attention due to its durable preservation and extremely high information density (bits per gram) properties. In this work, we propose a hybrid coding strategy comprising of generalized…

Information Theory · Computer Science 2021-12-20 Yixin Wang , Li Deng , Md. Noor-A-Rahim , Erry Gunawan , Yong L. Guan , Zhi P. Shi , Chueh L. Poh

Label prediction in neural networks (NNs) has O(n) complexity proportional to the number of classes. This holds true for classification using fully connected layers and cosine similarity with some set of class prototypes. In this paper we…

Machine Learning · Computer Science 2026-04-07 Nikita Gabdullin , Ilya Androsov

We consider a multi-stage distributed detection scenario, where $n$ sensors and a fusion center (FC) are deployed to accomplish a binary hypothesis test. At each time stage, local sensors generate binary messages, assumed to be spatially…

Signal Processing · Electrical Eng. & Systems 2023-01-04 Guangyang Zeng , Xiaoqiang Ren , Junfeng Wu

Graph Convolutional Networks (GCNs) and their variants have experienced significant attention and have become the de facto methods for learning graph representations. GCNs derive inspiration primarily from recent deep learning approaches,…

Machine Learning · Computer Science 2019-06-21 Felix Wu , Tianyi Zhang , Amauri Holanda de Souza , Christopher Fifty , Tao Yu , Kilian Q. Weinberger

The field of computational pathology has witnessed great advancements since deep neural networks have been widely applied. These networks usually require large numbers of annotated data to train vast parameters. However, it takes…

Computer Vision and Pattern Recognition · Computer Science 2022-08-11 Yixiao Zhang , Adam Kortylewski , Qing Liu , Seyoun Park , Benjamin Green , Elizabeth Engle , Guillermo Almodovar , Ryan Walk , Sigfredo Soto-Diaz , Janis Taube , Alex Szalay , Alan Yuille

Because of the decreasing cost and high digital resolution, next-generation sequencing (NGS) is expected to replace the traditional hybridization-based microarray technology. For genetics study, the first-step analysis of NGS data is often…

Applications · Statistics 2014-01-13 Zhigen Zhao , Wei Wang , Zhi Wei

DNA storage is now being considered as a new archival storage method for its durability and high information density, but still facing some challenges like high costs and low throughput. By reducing sequencing sample size for decoding…

Information Theory · Computer Science 2025-04-22 Ruiying Cao , Xin Chen

This paper is dedicated to lossless data compression with probability estimation using neural networks. First, we propose a probability estimation architecture based on a chain of neural predictors, so that each unit of the chain is defined…

Information Theory · Computer Science 2026-04-20 Yuriy Kim , Evgeny Belyaev

The Closest String Problem is an NP-hard problem that aims to find a string that has the minimum distance from all sequences that belong to the given set of strings. Its applications can be found in coding theory, computational biology, and…

Artificial Intelligence · Computer Science 2024-07-19 Alireza Abdi , Marko Djukanovic , Hesam Tahmasebi Boldaji , Hadis Salehi , Aleksandar Kartelj

Even though probabilistic treatments of neural networks have a long history, they have not found widespread use in practice. Sampling approaches are often too slow already for simple networks. The size of the inputs and the depth of typical…

Computer Vision and Pattern Recognition · Computer Science 2018-05-30 Jochen Gast , Stefan Roth

We prove that longest common prefix (LCP) information can be stored in much less space than previously known. More precisely, we show that in the presence of the text and the suffix array, o(n) additional bits are sufficient to answer…

Data Structures and Algorithms · Computer Science 2010-02-19 Johannes Fischer

DNA storage technology offers new possibilities for addressing massive data storage due to its high storage density, long-term preservation, low maintenance cost, and compact size. To improve the reliability of stored information, base…

Machine Learning · Computer Science 2024-09-24 Bowen Liu , Jiankun Li

The dominant approach to generating from language models subject to some constraint is locally constrained decoding (LCD), incrementally sampling tokens at each time step such that the constraint is never violated. Typically, this is…

The computational problem of inferring the full haplotype of a cell starting from read sequencing data is known as haplotype assembly, and consists in assigning all heterozygous Single Nucleotide Polymorphisms (SNPs) to exactly one of the…

Parallelization techniques have become ubiquitous for accelerating inference and training of deep neural networks. Despite this, several operations are still performed in a sequential manner. For instance, the forward and backward passes…

Machine Learning · Computer Science 2023-10-30 Federico Danieli , Miguel Sarabia , Xavier Suau , Pau Rodríguez , Luca Zappella