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In the paradigm of multi-task learning, mul- tiple related prediction tasks are learned jointly, sharing information across the tasks. We propose a framework for multi-task learn- ing that enables one to selectively share the information…

Machine Learning · Computer Science 2012-07-03 Abhishek Kumar , Hal Daume

While meta-analyzing retrospective cancer patient cohorts, an investigation of differences in the expressions of target oncogenes across cancer subtypes is of substantial interest because the results may uncover novel tumorigenesis…

Methodology · Statistics 2023-07-03 Subharup Guha , David C. Christiani , S. V. Subramanian , Yi Li

We propose a general and formal statistical framework for multiple tests of association between known fixed features of a genome and unknown parameters of the distribution of variable features of this genome in a population of interest. The…

Applications · Statistics 2008-12-18 Sandrine Dudoit , Sündüz Keleş , Mark J. van der Laan

In this article, we consider the problem of testing the independence between two random variables. Our primary objective is to develop tests that are highly effective at detecting associations arising from explicit or implicit functional…

Methodology · Statistics 2025-02-21 Seetharaman P , Sagnik Das , Angshuman Roy

The interactions between three or more random variables are often nontrivial, poorly understood, and yet, are paramount for future advances in fields such as network information theory, neuroscience, genetics and many others. In this work,…

Information Theory · Computer Science 2016-04-20 Fernando Rosas , Vasilis Ntranos , Christopher J. Ellison , Sofie Pollin , Marian Verhelst

This paper presents a general framework for modeling dependence in multivariate time series. Its fundamental approach relies on decomposing each signal in a system into various frequency components and then studying the dependence…

Methodology · Statistics 2021-04-01 Hernando Ombao , Marco Pinto

It is becoming increasingly common for researchers to consider incorporating external information from large studies to improve the accuracy of statistical inference instead of relying on a modestly sized dataset collected internally. With…

Methodology · Statistics 2021-07-20 Tian Gu , Jeremy M. G. Taylor , Bhramar Mukherjee

Developing effective multimodal data fusion strategies has become increasingly essential for improving the predictive power of statistical machine learning methods across a wide range of applications, from autonomous driving to medical…

Machine Learning · Computer Science 2025-07-29 Ziyi Liang , Annie Qu , Babak Shahbaba

Multivariate meta-analysis is gaining prominence in evidence synthesis research because it enables simultaneous synthesis of multiple correlated outcome data, and random-effects models have generally been used for addressing between-studies…

Methodology · Statistics 2021-07-14 Hisashi Noma , Kengo Nagashima , Toshi A. Furukawa

Decomposing knowledge into interchangeable pieces promises a generalization advantage when there are changes in distribution. A learning agent interacting with its environment is likely to be faced with situations requiring novel…

Machine Learning · Computer Science 2021-05-20 Kanika Madan , Nan Rosemary Ke , Anirudh Goyal , Bernhard Schölkopf , Yoshua Bengio

Background: Classifications in meta-research enable researchers to cope with an increasing body of scientific knowledge. They provide a framework for, e.g., distinguishing methods, reports, reproducibility, and evaluation in a knowledge…

Software Engineering · Computer Science 2022-09-22 Angelika Kaplan , Thomas Kühn , Ralf Reussner

The paramount importance of replicating associations is well recognized in the genome-wide associaton (GWA) research community, yet methods for assessing replicability of associations are scarce. Published GWA studies often combine…

Methodology · Statistics 2014-04-30 Ruth Heller , Daniel Yekutieli

We present a framework consisting of three approaches that can enhance meta-analyses: 1) scoping reviews (evidence map), 2) bibliometrics, and 3) alternative impact metrics. These three "enrichment" approaches facilitate the research…

Digital Libraries · Computer Science 2023-12-05 Yefeng Yang , Malgorzata Lagisz , Shinichi Nakagawa

The combination of multiple classifiers using ensemble methods is increasingly important for making progress in a variety of difficult prediction problems. We present a comparative analysis of several ensemble methods through two case…

Machine Learning · Computer Science 2013-09-20 Sean Whalen , Gaurav Pandey

As deep learning applications continue to become more diverse, an interesting question arises: Can general problem solving arise from jointly learning several such diverse tasks? To approach this question, deep multi-task learning is…

Machine Learning · Computer Science 2019-10-29 Elliot Meyerson , Risto Miikkulainen

There is an extensive literature on methods for meta-analysis of diagnostic studies, but it mainly focuses on a single test. However, the better understanding of a particular disease has led to the development of multiple tests. A…

Methodology · Statistics 2020-10-19 Aristidis K. Nikoloulopoulos

Meta-analyses play a crucial part in empirical science, enabling researchers to synthesize evidence across studies and draw more precise and generalizable conclusions. Despite their importance, access to advanced meta-analytic methodology…

Methodology · Statistics 2025-09-15 František Bartoš , Eric-Jan Wagenmakers , Wolfgang Viechtbauer

Consider making a prediction over new test data without any opportunity to learn from a training set of labelled data - instead given access to a set of expert models and their predictions alongside some limited information about the…

Machine Learning · Computer Science 2022-10-12 Alex J. Chan , Mihaela van der Schaar

When estimating causal effects using observational data, it is desirable to replicate a randomized experiment as closely as possible by obtaining treated and control groups with similar covariate distributions. This goal can often be…

Methodology · Statistics 2010-10-28 Elizabeth A. Stuart

Empirical claims often rely on one population, design, and analysis. Many-analysts, multiverse, and robustness studies expose how results can vary across plausible analytic choices. Synthesizing these results, however, is nontrivial as all…

Methodology · Statistics 2025-11-24 František Bartoš , Suzanne Hoogeveen , Alexandra Sarafoglou , Samuel Pawel