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This study aims to develop a digital twin (DT) framework to enhance adaptive proton stereotactic body radiation therapy (SBRT) for prostate cancer. Prostate SBRT has emerged as a leading option for external beam radiotherapy due to its…

Bose-Einstein condensate (BEC)-based atom interferometry exploits low temperatures and long coherence lengths to facilitate high-precision measurements. Progress in atom interferometry promises improvements in navigational devices like…

Quantum Gases · Physics 2021-11-25 Mary Clare Cassidy , Malcolm G. Boshier , Lee E. Harrell

Fast dose calculation is critical for online and real time adaptive therapy workflows. While modern physics-based dose algorithms must compromise accuracy to achieve low computation times, deep learning models can potentially perform dose…

Medical Physics · Physics 2023-07-19 Oscar Pastor-Serrano , Peng Dong , Charles Huang , Lei Xing , Zoltán Perkó

We investigate the ray dynamics in an optical cavity when a ray splitting mechanism is present. The cavity is a conventional two-mirror stable resonator and the ray splitting is achieved by inserting an optical beam splitter perpendicular…

Optics · Physics 2009-11-10 G. Puentes , A. Aiello , J. P. Woerdman

Purpose: Fast kV-switching (FKS) and dual-layer flat-panel detector (DL-FPD) technologies have been actively studied as promising dual-energy solutions for FPD-based cone-beam computed tomography (CBCT). However, CBCT spectral imaging is…

Medical Physics · Physics 2024-01-03 Hao Zhou , Li Zhang , Zhilei Wang , Hewei Gao

Low-dose computed tomography (LDCT) reduces radiation exposure but suffers from image artifacts and loss of detail due to quantum and electronic noise, potentially impacting diagnostic accuracy. Transformer combined with diffusion models…

Image and Video Processing · Electrical Eng. & Systems 2025-07-01 Qiqing Liu , Guoquan Wei , Zekun Zhou , Yiyang Wen , Liu Shi , Qiegen Liu

Intraoperative optical imaging is a localization technique for the functional areas of the human brain cortex during neurosurgical procedures. These areas can be assessed by monitoring cerebral hemodynamics and metabolism. A robust…

Intraoperative Cone Beam Computed Tomography (CBCT) provides a reliable 3D anatomical context essential for interventional planning. However, its static nature fails to provide continuous monitoring of soft-tissue deformations induced by…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Feng Li , Ziyuan Li , Zhongliang Jiang , Nassir Navab , Yuan Bi

Volumetry is one of the principal downstream applications of 3D medical image segmentation, for example, to detect abnormal tissue growth or for surgery planning. Conformal Prediction is a promising framework for uncertainty quantification,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-30 Benjamin Lambert , Florence Forbes , Senan Doyle , Michel Dojat

We demonstrate an object tracking method for 3D images with fixed computational cost and state-of-the-art performance. Previous methods predicted transformation parameters from convolutional layers. We instead propose an architecture that…

Computer Vision and Pattern Recognition · Computer Science 2021-09-28 Daniel Moyer , Esra Abaci Turk , P Ellen Grant , William M. Wells , Polina Golland

Limited-view artefacts are commonly present in optoacoustic tomography images, mainly due to practical geometrical and physical constraints imposed by the imaging systems as well as limited light penetration into large optically opaque…

Optics · Physics 2015-12-11 X L Dean-Ben , L Ding , D Razansky

Varian Medical Systems has manufactured and recently put into operation a clinically-applicable solution for image-guided radiation therapy. Cone-beam CT imaging, one of the operation modes of the imaging unit of this device, aims at…

Medical Physics · Physics 2007-05-23 Evangelos Matsinos , Wolfgang Kaissl

Purpose: Digital phantoms are one of the key components of virtual imaging trials (VITs) that aim to assess and optimize new medical imaging systems and algorithms. However, these phantoms vary in their voxel resolution, appearance, and…

Medical Physics · Physics 2024-02-02 Amar Kavuri , Mini Das

Diffusion tensor imaging (DTI) holds significant importance in clinical diagnosis and neuroscience research. However, conventional model-based fitting methods often suffer from sensitivity to noise, leading to decreased accuracy in…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Jialong Li , Zhicheng Zhang , Yunwei Chen , Qiqi Lu , Ye Wu , Xiaoming Liu , QianJin Feng , Yanqiu Feng , Xinyuan Zhang

Background: Windowed Fourier decompositions (WFD) are widely used in measuring stationary and non-stationary spectral phenomena and in describing pairwise relationships among multiple signals. Although a variety of WFDs see frequent…

Quantitative Methods · Quantitative Biology 2019-01-30 Christopher K. Kovach , Phillip E. Gander

The large volume of electroencephalograph (EEG) data produced by brain-computer interface (BCI) systems presents challenges for rapid transmission over bandwidth-limited channels in Internet of Things (IoT) networks. To address the issue,…

Signal Processing · Electrical Eng. & Systems 2025-03-14 Xin Zhu , Hongyi Pan , Ahmet Enis Cetin

X-ray micro tomography is a non-destructive, three-dimensional inspection technique applied across a vast range of fields and disciplines, ranging from research to industrial, encompassing engineering, biology and medical research.…

Medical differential phase contrast x-ray imaging (DPCI) promises improved soft-tissue contrast at lower x-ray dose. The dose strongly depends on both the angular sensitivity and on the visibility of a grating-based Talbot-Lau…

Medical Physics · Physics 2016-03-23 Oliver Preusche

Cone beam CT (CBCT) has been widely used for patient setup in image guided radiation therapy (IGRT). Radiation dose from CBCT scans has become a clinical concern. The purposes of this study are 1) to commission a GPU-based Monte Carlo (MC)…

The method of filtered back projection (FBP) is a widely used reconstruction technique in X-ray computerized tomography (CT), which is particularly important in clinical diagnostics. To reduce scanning times and radiation doses in medical…

Numerical Analysis · Mathematics 2024-08-14 Matthias Beckmann , Judith Nickel