Related papers: A remote response of ATP hydrolysis
Exergy is a thermodynamic quantity useful to obtain information on the work from any process. The analyses of irreversibility are important in the designing and development of the productive processes for the economic growth, but they play…
Autophagy is a conserved biological stress response in mammalian cells that is responsible for clearing damaged proteins and organelles from the cytoplasm and recycling their contents via the lysosomal pathway. In cases of mild stress,…
Water diffusion through membrane proteins is a key aspect of cellular function. Essential processes of cellular metabolism are driven by osmotic pressure, which depends on water channels. Membrane proteins such as aquaporins (AQPs) are…
The energy conversion efficiency of far-from-equilibrium systems is generally limited by irreversible thermodynamic fluxes that make contact with different heat baths. For complex systems, the states of the maximum efficiency and the…
Molecular beam experiments that use low-temperature bolometers as (energy-) detectors are well suited to the study of physisorption and recombination of hydrogen on low-temperature surfaces. Experiments where this technique is combined with…
A new empirical potential for efficient, large scale molecular dynamics simulation of water is presented. The HIPPO (Hydrogen-like Intermolecular Polarizable POtential) force field is based upon the model electron density of a hydrogen-like…
In this work we study the assisted translocation of a polymer across a membrane nanopore, inside which a molecular motor exerts a force fuelled by the hydrolysis of ATP molecules. In our model the motor switches to its active state for a…
Using some knowledge of multiplicity disributions for high energy reactions, it is possible to propose a simple analytical model of particle production by strong external sources. The model describes qualitatively most peculiar properties…
Nowadays hydroelectric energy is one of the best energy sources: it is cleaner, safer and more programmable than other sources. For this reason, its manage could not be done in an approssimative way, but advance mathematical models must be…
Through in-depth thinking and reasoning about the conditions required for cells to maintain unchanged material distribution, it is concluded that life metabolic reactions require high information content. However, the self-replication of a…
Herein (the first part of my work), I debunk the long-standing hypotheses that explain mitochondrial oxidative phosphorylation. Simple calculations point out that mitochondria are highly proton-deficient microcosms and therefore, elaborate…
Biological systems perform an astonishing array of dynamical processes -- including development and repair, regulation, behavior and motor control, sensing and signaling, and adaptation, among others. Powered by the transduction of stored…
The weighty evidences of specific transformations of the thermal motion in pure water in the physiological temperature interval (PTI) from (30 +(-) 3)o C to (42 +(-) 3)o C for warm-blooded organisms are presented. It is shown that near the…
Cellular metabolism is globally regulated by various currency metabolites such as ATP, GTP, and NAD(P)H. These metabolites cycle between charged (high-energy) and uncharged (low-energy) states to mediate energy transfer. While distinct…
The concept of entropy has been pivotal in the formulation of thermodynamics. For systems driven away from thermal equilibrium, a comparable role is played by entropy production and dissipation. Here we provide a comprehensive picture how…
We present the relatively less known thermodynamic concept of exergy in the context of ecology and sustainability. To this end, we first very briefly outline thermodynamics as it arose historically via engineering studies. This enables us…
The utilization of glycolysis in aerobic conditions have been a subject of debate for more than a century. A hypothesis supported by previous data is that glycolysis has a higher rate of ATP production per protein mass and per occupied…
In this paper we demonstrate how chemical free energy can be produced by a geological process. We provide a thermodynamic framework in which to assess how life emerged at the off-axis hydrothermal vent system; the RNA - clays system has…
Biological signaling is imagined as a combination of activation and transport. The former is triggered by local molecular interactions and the latter is the result of molecular diffusion. However, other fundamental physical principles of…
Chemically active droplets provide simple models for cell-like systems that can grow and divide. Such active droplet systems are driven away from thermodynamic equilibrium and turn over chemically, which corresponds to a simple metabolism.…