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The quintessential property of neuronal systems is their intensive patterns of selective synaptic connections. The current work describes a physics-based approach to neuronal shape modeling and synthesis and its consideration for the…

Neurons and Cognition · Quantitative Biology 2009-11-10 Luciano da Fontoura Costa , Regina Celia Coelho

Understanding how biological constraints shape neural computation is a central goal of computational neuroscience. Spatially embedded recurrent neural networks provide a promising avenue to study how modelled constraints shape the combined…

Neural and Evolutionary Computing · Computer Science 2024-09-27 Cornelia Sheeran , Andrew S. Ham , Duncan E. Astle , Jascha Achterberg , Danyal Akarca

Over the decades, Functional Analysis has been enriched and inspired on account of demands from neighboring fields, within mathematics, harmonic analysis (wavelets and signal processing), numerical analysis (finite element methods,…

Functional Analysis · Mathematics 2015-08-25 Palle Jorgensen , Feng Tian

Many empirical examples of regression discontinuity (RD) designs concern a continuous treatment variable, but the theoretical aspects of such models are less studied. This study examines the identification and estimation of the structural…

Econometrics · Economics 2022-07-19 Haitian Xie

Understanding the relation between cortical neuronal network structure and neuronal activity is a fundamental unresolved question in neuroscience, with implications to our understanding of the mechanism by which neuronal networks evolve…

Accurate models of mechanical system dynamics are often critical for model-based control and reinforcement learning. Fully data-driven dynamics models promise to ease the process of modeling and analysis, but require considerable amounts of…

Machine Learning · Computer Science 2021-04-19 A. René Geist , Sebastian Trimpe

Understanding the relationship between the dynamics of neural processes and the anatomical substrate of the brain is a central question in neuroscience. On the one hand, modern neuroimaging technologies, such as diffusion tensor imaging,…

We consider analysis of dependent functional data that are correlated because of a longitudinal-based design: each subject is observed at repeated time visits and for each visit we record a functional variable. We propose a novel…

Methodology · Statistics 2015-06-30 So Young Park , Ana-Maria Staicu

The analysis of spatial point patterns that occur in the network domain have recently gained much attraction and various intensity functions and measures have been proposed. However, the linkage of spatial network statistics to regression…

Applications · Statistics 2016-07-25 Matthias Eckardt , Jorge Mateu

Discovering causal relationship using multivariate functional data has received a significant amount of attention very recently. In this article, we introduce a functional linear structural equation model for causal structure learning when…

Methodology · Statistics 2023-11-01 Saptarshi Roy , Raymond K. W. Wong , Yang Ni

Key to structured prediction is exploiting the problem structure to simplify the learning process. A major challenge arises when data exhibit a local structure (e.g., are made by "parts") that can be leveraged to better approximate the…

Machine Learning · Statistics 2019-06-03 Carlo Ciliberto , Francis Bach , Alessandro Rudi

Large-scale white matter pathways crisscrossing the cortex create a complex pattern of connectivity that underlies human cognitive function. Generative mechanisms for this architecture have been difficult to identify in part because little…

Neurons and Cognition · Quantitative Biology 2015-06-16 Florian Klimm , Danielle S. Bassett , Jean M. Carlson , Peter J. Mucha

Traditional Functional Principal Component Analysis typically focuses on densely observed univariate functional data, yet many applications, particularly in longitudinal studies, involve multivariate functional data observed sparsely and…

Methodology · Statistics 2026-03-23 Uche Mbaka , Michelle Carey

Constructing generative models for functional observations is an important task in statistical functional analysis. In general, functional data contains both phase (or x or horizontal) and amplitude (or y or vertical) variability. Tradi-…

Computation · Statistics 2019-04-26 J. Derek Tucker , Wei Wu , Anuj Srivastava

Identifying a coupled dynamical system out of many plausible candidates, each of which could serve as the underlying generator of some observed measurements, is a profoundly ill posed problem that commonly arises when modelling real world…

Neurons and Cognition · Quantitative Biology 2019-09-17 Amirhossein Jafarian , Peter Zeidman , Vladimir Litvak , Karl Friston

Parameter estimation in structural dynamics generally involves inferring the values of physical, geometric, or even customized parameters based on first principles or expert knowledge, which is challenging for complex structural systems. In…

Computational Engineering, Finance, and Science · Computer Science 2025-04-08 Mingyuan Zhou , Haoze Song , Wenjing Ye , Wei Wang , Zhilu Lai

We consider functional linear regression models where functional outcomes are associated with scalar predictors by coefficient functions with shape constraints, such as monotonicity and convexity, that apply to sub-domains of interest. To…

Methodology · Statistics 2025-05-09 Kyunghee Han , Yeonjoo Park , Soo-Young Kim

With our ability to record more neurons simultaneously, making sense of these data is a challenge. Functional connectivity is one popular way to study the relationship between multiple neural signals. Correlation-based methods are a set of…

Neurons and Cognition · Quantitative Biology 2017-06-09 Tiger W. Lin , Anup Das , Giri P. Krishnan , Maxim Bazhenov , Terrence J. Sejnowski

This paper describes a relatively simple way of allowing a brain model to self-organise its concept patterns through nested structures. Time is a key element and a simulator would be able to show how patterns may form and then fire in…

Neural and Evolutionary Computing · Computer Science 2014-09-05 Kieran Greer

Encoding models are used for predicting brain activity in response to sensory stimuli with the objective of elucidating how sensory information is represented in the brain. Encoding models typically comprise a nonlinear transformation of…

Neurons and Cognition · Quantitative Biology 2017-03-13 Umut Güçlü , Marcel A. J. van Gerven