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This study proposes a novel, integrative framework for patient-centered data science in the digital health era. We developed a multidimensional model that combines traditional clinical data with patient-reported outcomes, social…
The establishment of links between data (e.g., patient records) and Web resources (e.g., literature) and the proper visualization of such discovered knowledge is still a challenge in most Life Science domains (e.g., biomedicine). In this…
In this article, we explain in detail the internal structures and databases of a smart health application. Moreover, we describe how to generate a statistically sound synthetic dataset using real-world medical data.
The proliferation of consumer health devices such as smart watches, sleep monitors, smart scales, etc, in many countries, has not only led to growing interest in health monitoring, but also to the development of a countless number of…
Objective: To (1) demonstrate the implementation of a data science platform built on open-source technology within a large, academic healthcare system and (2) describe two computational healthcare applications built on such a platform.…
In the past few decades, the life sciences have experienced an unprecedented accumulation of data, ranging from genomic sequences and proteomic profiles to heavy-content imaging, clinical assays, and commercial biological products for…
The global shortage and uneven distribution of medical expertise continue to hinder equitable access to accurate diagnostic care. While existing intelligent diagnostic system have shown promise, most struggle with dual-user interaction, and…
This article presents our steps to integrate complex and partly unstructured medical data into a clinical research database with subsequent decision support. Our main application is an integrated faceted search tool, accompanied by the…
The fundamental aim of the healthcare sector is to incorporate different technologies to observe and keep a track of the various clinical parameters of the patients in day to day life. Distant patient observation applications are becoming…
The escalating cost, extended timelines, and low success rates in pharmaceutical research demand a fundamental rethinking of biotechnology R&D infrastructure. This chapter introduces the concept of the AI-Integrated Biotechnology Hub, a…
Medical experts may use Artificial Intelligence (AI) systems with greater trust if these are supported by contextual explanations that let the practitioner connect system inferences to their context of use. However, their importance in…
Clinicians are interested in better understanding complex diseases, such as cancer or rare diseases, so they need to produce and exchange data to mutualize sources and join forces. To do so and ensure privacy, a natural way consists in…
Connected health is a multidisciplinary approach focused on health management, prioritizing pa-tient needs in the creation of tools, services, and treatments. This paradigm ensures proactive and efficient care by facilitating the timely…
With the advancement of internet communication and telemedicine, people are increasingly turning to the web for various healthcare activities. With an ever-increasing number of diseases and symptoms, diagnosing patients becomes challenging.…
The Linked Clinical Trials (LinkedCT) project aims at publishing the first open semantic web data source for clinical trials data. The database exposed by LinkedCT is generated by (1) transforming existing data sources of clinical trials…
Data integration among various stakeholders in the healthcare space remains a challenge, despite the impressive advances in Health AI in the past decade. There is a lot of ``messy'' non-standard but structured data that are continually…
Data management can be a complex challenge in fields such as bioinformatics and health sciences, which continuously generate extensive heterogeneous datasets. In the context of collaborative global health initiatives, secure storage and…
A promising application of AI to healthcare is the retrieval of information from electronic health records (EHRs), e.g. to aid clinicians in finding relevant information for a consultation or to recruit suitable patients for a study. This…
The proliferation of sensor technologies and advancements in data collection methods have enabled the accumulation of very large amounts of data. Increasingly, these datasets are considered for scientific research. However, the design of…
In this paper, we develop a novel logic-based approach to detecting high-level temporally extended events from timestamped data and background knowledge. Our framework employs logical rules to capture existence and termination conditions…