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We study the Stochastic Gradient Langevin Dynamics (SGLD) algorithm for non-convex optimization. The algorithm performs stochastic gradient descent, where in each step it injects appropriately scaled Gaussian noise to the update. We analyze…

Machine Learning · Computer Science 2018-04-10 Yuchen Zhang , Percy Liang , Moses Charikar

Coarse-grained (CG) models are simplified representations of soft matter systems that are commonly employed to overcome size and time limitations in computational studies. Many approaches have been developed to construct and parametrise…

Statistical Mechanics · Physics 2022-09-27 Piero Luchi , Roberto Menichetti , Gianluca Lattanzi , Raffaello Potestio

We introduce exponential numerical integration methods for stiff stochastic dynamical systems of the form $d\mathbf{z}_t = L(t)\mathbf{z}_tdt + \mathbf{f}(t)dt + Q(t)d\mathbf{W}_t$. We consider the setting of time-varying operators $L(t),…

Numerical Analysis · Mathematics 2022-12-20 Dev Jasuja , P. J. Atzberger

In this study, we present a comprehensive analysis of the motion of a tagged monomer within a Gaussian semiflexible polymer model. We carefully derived the generalized Langevin Equation (GLE) that governs the motion of a tagged central…

Soft Condensed Matter · Physics 2024-07-23 Xavier Durang , Jae-Hyung Jeon

We develop a formulation for molecular dynamics, Langevin, and hybrid Monte Carlo algorithms in the recently proposed generalized ensemble that is based on a physically motivated realisation of Tsallis weights. The effectiveness of the…

Biological Physics · Physics 2016-09-08 Ulrich H. E. Hansmann , Frank Eisenmenger , Yuko Okamoto

This work presents an extension of discretely entropy stable discontinuous Galerkin (DG) methods to the resistive magnetohydrodynamics (MHD) equations. Although similar to the compressible Navier-Stokes equations at first sight, there are…

Numerical Analysis · Mathematics 2017-11-16 Marvin Bohm , Andrew R. Winters , Dominik Derigs , Gregor J. Gassner , Stefanie Walch , Joachim Saur

We provide an analytical framework for analyzing the quality of stochastic Verlet-type integrators for simulating the Langevin equation. Focusing only on basic objective measures, we consider the ability of an integrator to correctly…

Computational Physics · Physics 2026-02-12 Niels Grønbech-Jensen

The generalized linear models (GLMs) are widely used in statistical analysis and the related design issues are undoubtedly challenging. The state-of-the-art works mostly apply to design criteria on the estimates of regression coefficients.…

Methodology · Statistics 2020-04-21 Yiou Li , Xinwei Deng

Modern biomedical datasets are increasingly high dimensional and exhibit complex correlation structures. Generalized Linear Mixed Models (GLMMs) have long been employed to account for such dependencies. However, proper specification of the…

The Dynamical Graph Grammar (DGG) formalism can describe complex system dynamics with graphs that are mapped into a master equation. An exact stochastic simulation algorithm may be used, but it is slow for large systems. To overcome this…

Quantitative Methods · Quantitative Biology 2024-07-16 Eric Medwedeff , Eric Mjolsness

The linear Markov Decision Process (MDP) framework offers a principled foundation for reinforcement learning (RL) with strong theoretical guarantees and sample efficiency. However, its restrictive assumption-that both transition dynamics…

Machine Learning · Statistics 2025-06-03 Sinian Zhang , Kaicheng Zhang , Ziping Xu , Tianxi Cai , Doudou Zhou

This tutorial provides an overview of the generalized Lyapunov method (GLM) for analyzing input-to-state stability (ISS) of partial differential equations (PDEs). We begin by revisiting the classical Lyapunov method and the standard…

Optimization and Control · Mathematics 2026-05-05 Jun Zheng , Guchuan Zhu

Stochastic Gradient Langevin Dynamics (SGLD) is a popular variant of Stochastic Gradient Descent, where properly scaled isotropic Gaussian noise is added to an unbiased estimate of the gradient at each iteration. This modest change allows…

Machine Learning · Computer Science 2017-06-06 Maxim Raginsky , Alexander Rakhlin , Matus Telgarsky

Monte Carlo simulations are widely used to simulate complex molecular systems, but standard approaches suffer from metastability. Lately, the use of non-local proposal updates in a collective-variable (CV) space has been proposed in several…

Statistical Mechanics · Physics 2026-04-20 Christoph Schönle , Davide Carbone , Marylou Gabrié , Tony Lelièvre , Gabriel Stoltz

Graph Neural Networks (GNNs) have demonstrated significant success in graph learning and are widely adopted across various critical domains. However, the irregular connectivity between vertices leads to inefficient neighbor aggregation,…

Hardware Architecture · Computer Science 2025-06-27 Gongjian Sun , Mingyu Yan , Dengke Han , Runzhen Xue , Duo Wang , Xiaochun Ye , Dongrui Fan

The properties of molecules and materials containing light nuclei are affected by their quantum mechanical nature. Modelling these quantum nuclear effects accurately requires computationally demanding path integral techniques. Considerable…

Chemical Physics · Physics 2020-04-22 Venkat Kapil , David M. Wilkins , Jinggang Lan , Michele Ceriotti

Any first course on polymer physics teaches that the dynamics of a tagged monomer of a polymer is anomalously subdiffusive, i.e., the mean-square displacement of a tagged monomer increases as $t^\alpha$ for some $\alpha<1$ until the…

Soft Condensed Matter · Physics 2010-06-16 Debabrata Panja

Maximizing storage performance in geological carbon storage (GCS) is crucial for commercial deployment, but traditional optimization demands resource-intensive simulations, posing computational challenges. This study introduces the…

Machine Learning · Computer Science 2024-06-10 Zhongzheng Wang , Yuntian Chen , Guodong Chen , Dongxiao Zhang

While gradient-based discrete samplers are effective in sampling from complex distributions, they are susceptible to getting trapped in local minima, particularly in high-dimensional, multimodal discrete distributions, owing to the…

Machine Learning · Statistics 2025-05-21 Luxu Liang , Yuhang Jia , Feng Zhou

We present the Gaussian process dynamical mixture model (GPDMM) and show its utility in single-example learning of human motion data. The Gaussian process dynamical model (GPDM) is a form of the Gaussian process latent variable model…

Machine Learning · Computer Science 2025-06-18 Jesse St. Amand , Leonardo Gizzi , Martin A. Giese