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We study the problem usually referred to as group testing in the context of COVID-19. Given $n$ samples taken from patients, how should we select mixtures of samples to be tested, so as to maximize information and minimize the number of…

Methodology · Statistics 2020-05-14 Louis Abraham , Gary Bécigneul , Bernhard Schölkopf

In this paper, we consider the group testing problem with adaptive test designs and noisy outcomes. We propose a computationally efficient four-stage procedure with components including random binning, identification of bins containing…

Computation · Statistics 2019-11-11 Jonathan Scarlett

Accurate detection of infected individuals is one of the critical steps in stopping any pandemic. When the underlying infection rate of the disease is low, testing people in groups, instead of testing each individual in the population, can…

Group testing enables to identify infected individuals in a population using a smaller number of tests than individual testing. To achieve this, group testing algorithms commonly assume knowledge of the number of infected individuals;…

Information Theory · Computer Science 2023-05-16 Chaorui Yao , Pavlos Nikolopoulos , Christina Fragouli

In order to identify the infected individuals of a population, their samples are divided in equally sized groups called pools and a single laboratory test is applied to each pool. Individuals whose samples belong to pools that test negative…

Statistics Theory · Mathematics 2021-10-06 Inés Armendáriz , Pablo A. Ferrari , Daniel Fraiman , José M. Martínez , Silvina Ponce Dawson

We consider the nonadaptive group testing with N items, of which $K = \Theta(N^\theta)$ are defective. We study a test design in which each item appears in nearly the same number of tests. For each item, we independently pick L tests…

Information Theory · Computer Science 2018-09-26 Oliver Johnson , Matthew Aldridge , Jonathan Scarlett

Group testing is a well known search problem that consists in detecting up to $s$ defective elements of the set $[t]=\{1,\ldots,t\}$ by carrying out tests on properly chosen subsets of $[t]$. In classical group testing the goal is to find…

Information Theory · Computer Science 2016-07-05 A. G. D'yachkov , I. V. Vorobyev , N. A. Polyanskii , V. Yu. Shchukin

Group testing is one of the fundamental problems in coding theory and combinatorics in which one is to identify a subset of contaminated items from a given ground set. There has been renewed interest in group testing recently due to its…

Information Theory · Computer Science 2022-02-11 Mira Gonen , Michael Langberg , Alex Sprintson

The group testing problem is concerned with identifying a small set of infected individuals in a large population. At our disposal is a testing procedure that allows us to test several individuals together. In an idealized setting, a test…

Information Theory · Computer Science 2023-09-19 Oliver Gebhard , Oliver Johnson , Philipp Loick , Maurice Rolvien

The use of group testing to locate all instances of disease in a large population of blood samples was first considered seventy years ago. Since then, several methods have been used to approximate the minimum expected number of tests. The…

Applications · Statistics 2015-03-24 Seth Zimmerman

In the long-studied problem of combinatorial group testing, one is asked to detect a set of $k$ defective items out of a population of size $n$, using $m \ll n$ disjunctive measurements. In the non-adaptive setting, the most widely used…

Information Theory · Computer Science 2020-09-28 Mahdi Cheraghchi , Vasileios Nakos

Large scale disease screening is a complicated process in which high costs must be balanced against pressing public health needs. When the goal is screening for infectious disease, one approach is group testing in which samples are…

Applications · Statistics 2021-03-02 Gregory Haber , Yaakov Malinovsky , Paul S. Albert

We study the group test for DNA library screening based on probabilistic approach. Group test is a method of detecting a few positive items from among a large number of items, and has wide range of applications. In DNA library screening,…

Computation · Statistics 2010-04-27 Takafumi Kanamori , Hiroaki Uehara , Masakazu Jimbo

We have a large number of samples and we want to find the infected ones using as few number of tests as possible. We can use group testing which tells about a small group of people whether at least one of them is infected. Group testing is…

Quantitative Methods · Quantitative Biology 2020-05-07 Endre Csóka

In group testing, the task is to determine the distinguished members of a set of objects L by asking subset queries of the form ``does the subset Q of L contain a distinguished object?'' The primary biological application of group testing…

Combinatorics · Mathematics 2008-02-03 Emanuel Knill , S. Muthukrishnan

We study the problem of identifying a small set $k\sim n^\theta$, $0<\theta<1$, of infected individuals within a large population of size $n$ by testing groups of individuals simultaneously. All tests are conducted concurrently. The goal is…

Discrete Mathematics · Computer Science 2025-03-05 Amin Coja-Oghlan , Max Hahn-Klimroth , Lukas Hintze , Dominik Kaaser , Lena Krieg , Maurice Rolvien , Olga Scheftelowitsch

The main goal of group testing with inhibitors (GTI) is to efficiently identify a small number of defective items and inhibitor items in a large set of items. A test on a subset of items is positive if the subset satisfies some specific…

Information Theory · Computer Science 2019-02-12 Thach V. Bui , Minoru Kuribayashi , Mahdi Cheraghchi , Isao Echizen

We study the canonical problem of maximizing a stochastic submodular function subject to a cardinality constraint, where the goal is to select a subset from a ground set of items with uncertain individual performances to maximize their…

Data Structures and Algorithms · Computer Science 2019-05-10 Shreyas Sekar , Milan Vojnovic , Se-Young Yun

Consider the following Stochastic Score Classification Problem. A doctor is assessing a patient's risk of developing a certain disease, and can perform $n$ tests on the patient. Each test has a binary outcome, positive or negative. A…

Data Structures and Algorithms · Computer Science 2018-06-29 Dimitrios Gkenosis , Nathaniel Grammel , Lisa Hellerstein , Devorah Kletenik

We consider the problem of group testing (pooled testing), first introduced by Dorfman. For non-adaptive testing strategies, we refer to a non-defective item as `intruding' if it only appears in positive tests. Such items cause…

Probability · Mathematics 2023-09-19 Letian Yu , Fraser Daly , Oliver Johnson
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