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Tethered particle motion experiments are versatile single-molecule techniques enabling one to address in vitro the molecular properties of DNA and its interactions with various partners involved in genetic regulations. These techniques…

Biological Physics · Physics 2019-09-05 Manoel Manghi , Nicolas Destainville , Annaël Brunet

The design of fluid channel structures of reactors or separators of chemical processes is key to enhancing the mass transfer processes inside the devices. However, the systematic design of channel topological structures is difficult for…

Fluid Dynamics · Physics 2025-03-07 Chenhui Kou , Yuhui Yin , Min Zhu , Shengkun Jia , Yiqing Luo , Xigang Yuana , Lu Lu

We present a new adaptive resolution technique for efficient particle-based multiscale molecular dynamics (MD) simulations. The presented approach is tailor-made for molecular systems where atomistic resolution is required only in spatially…

Soft Condensed Matter · Physics 2007-05-23 Matej Praprotnik , Luigi Delle Site , Kurt Kremer

Knots are intricate structures that cannot be unambiguously distinguished with any single topological invariant. Momentum space knots, in particular, have been elusive due to their requisite finely tuned long-ranged hoppings. Even if…

Mesoscale and Nanoscale Physics · Physics 2020-12-04 Ching Hua Lee , Amanda Sutrisno , Tobias Hofmann , Tobias Helbig , Yuhan Liu , Yee Sin Ang , Lay Kee Ang , Xiao Zhang , Martin Greiter , Ronny Thomale

The simulation of high-energy physics collision events is a key element for data analysis at present and future particle accelerators. The comparison of simulation predictions to data allows looking for rare deviations that can be due to…

High Energy Physics - Experiment · Physics 2024-07-16 Francesco Vaselli , Filippo Cattafesta , Patrick Asenov , Andrea Rizzi

A method of {\it topological grammars} is proposed for multidimensional data approximation. For data with complex topology we define a {\it principal cubic complex} of low dimension and given complexity that gives the best approximation for…

Neural and Evolutionary Computing · Computer Science 2007-05-23 A. N. Gorban , N. R. Sumner , A. Y. Zinovyev

Topological data analysis (TDA) is a branch of computational mathematics, bridging algebraic topology and data science, that provides compact, noise-robust representations of complex structures. Deep neural networks (DNNs) learn millions of…

Mesoscale simulations of woven composites using parameterized analytical geometries offer a way to connect constituent material properties and their geometric arrangement to effective composite properties and performance. However, the…

Materials Science · Physics 2023-02-21 Collin W. Foster , Lincoln N. Collins , Francesco Panerai , Scott A. Roberts

Topological quantum computing has recently proven itself to be a powerful computational model when constructing viable architectures for large scale computation. The topological model is constructed from the foundation of a error correction…

Quantum Physics · Physics 2013-06-24 Simon J. Devitt , Kae Nemoto

Topological quantum computation may provide a robust approach for encoding and manipulating information utilizing the topological properties of anyonic quasi-particle excitations. We develop an efficient means to map between dense and…

Quantum Physics · Physics 2011-08-02 Haitan Xu , J. M. Taylor

We present a novel kernel-based machine learning algorithm for identifying the low-dimensional geometry of the effective dynamics of high-dimensional multiscale stochastic systems. Recently, the authors developed a mathematical framework…

Dynamical Systems · Mathematics 2020-02-04 Andreas Bittracher , Stefan Klus , Boumediene Hamzi , Péter Koltai , Christof Schütte

Quantum compiling, a process that decomposes the quantum algorithm into a series of hardware-compatible commands or elementary gates, is of fundamental importance for quantum computing. We introduce an efficient algorithm based on deep…

Quantum Physics · Physics 2020-10-22 Yuan-Hang Zhang , Pei-Lin Zheng , Yi Zhang , Dong-Ling Deng

A core challenge in the interpretation of deep neural networks is identifying commonalities between the underlying algorithms implemented by distinct networks trained for the same task. Motivated by this problem, we introduce DYNAMO, an…

Machine Learning · Computer Science 2023-03-01 Jordan Cotler , Kai Sheng Tai , Felipe Hernández , Blake Elias , David Sussillo

We perform topological data analysis on the internal states of convolutional deep neural networks to develop an understanding of the computations that they perform. We apply this understanding to modify the computations so as to (a) speed…

Machine Learning · Computer Science 2018-11-06 Gunnar Carlsson , Rickard Brüel Gabrielsson

A parameterization strategy for molecular models on the basis of force fields is proposed, which allows a rapid development of models for small molecules by using results from quantum mechanical (QM) ab initio calculations and thermodynamic…

Chemical Physics · Physics 2009-04-22 Bernhard Eckl , Jadran Vrabec , Hans Hasse

We present a 3D, topological picture-language for quantum information. Our approach combines charged excitations carried by strings, with topological properties that arise from embedding the strings in the interior of a three-dimensional…

Quantum Physics · Physics 2018-03-19 Zhengwei Liu , Alex Wozniakowski , Arthur Jaffe

Graph neural networks are emerging as promising methods for modeling molecular graphs, in which nodes and edges correspond to atoms and chemical bonds, respectively. Recent studies show that when 3D molecular geometries, such as bond…

Machine Learning · Computer Science 2021-10-06 Zhao Xu , Youzhi Luo , Xuan Zhang , Xinyi Xu , Yaochen Xie , Meng Liu , Kaleb Dickerson , Cheng Deng , Maho Nakata , Shuiwang Ji

Topological data analysis offers a rich source of valuable information to study vision problems. Yet, so far we lack a theoretically sound connection to popular kernel-based learning techniques, such as kernel SVMs or kernel PCA. In this…

Machine Learning · Statistics 2014-12-24 Jan Reininghaus , Stefan Huber , Ulrich Bauer , Roland Kwitt

Engineering synthetic dimensions, where the physics of additional spatial dimensions is simulated within the internal states of a quantum system, allows the realisation of phenomena not otherwise accessible in experiments. Ultracold…

Many biological and medical tasks require the delineation of 3D curvilinear structures such as blood vessels and neurites from image volumes. This is typically done using neural networks trained by minimizing voxel-wise loss functions that…

Computer Vision and Pattern Recognition · Computer Science 2022-12-27 Doruk Oner , Hussein Osman , Mateusz Kozinski , Pascal Fua