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Brownian dynamics simulations are an increasingly popular tool for understanding spatially-distributed biochemical reaction systems. Recent improvements in our understanding of the cellular environment show that volume exclusion effects are…

Chemical Physics · Physics 2017-09-13 Stephen Smith , Ramon Grima

A numerical method to efficiently solve for mixing and reaction of scalars in a two-dimensional flow field at large P\'eclet numbers but otherwise arbitrary Damk\"ohler numbers is reported. We consider a strip of one reactant in a pool of…

Fluid Dynamics · Physics 2016-06-17 Aditya Bandopadhyay , Tanguy Le Borgne , Yves Méheust

The problem of mass diffusion in layered systems has relevance to applications in different scientific disciplines, e.g., chemistry, material science, soil science, and biomedical engineering. The mathematical challenge in these type of…

Statistical Mechanics · Physics 2020-10-28 Oded Farago

We investigate numerically, using the bond-fluctuation model, the adsorption of many random AB--copolymers with excluded volume interactions at the interface between two solvents. We find two regimes, controlled by the total number of…

Soft Condensed Matter · Physics 2007-05-23 Gongwen Peng , Jens-Uwe Sommer , Alexander Blumen

Understanding frictional phenomena is a fascinating fundamental problem with huge potential impact on energy saving. Such an understanding requires monitoring what happens at the sliding buried interface, which is almost inaccessible by…

Mesoscale and Nanoscale Physics · Physics 2023-04-24 Seiji Kajita , Alberto Pacini , Gabriele Losi , Nobuaki Kikkawa , Maria Clelia Righi

We present the first exact simulation method for multidimensional reflected Brownian motion (RBM). Exact simulation in this setting is challenging because of the presence of correlated local-time-like terms in the definition of RBM. We…

Probability · Mathematics 2017-08-31 Jose Blanchet , Karthyek R. A. Murthy

As a universal quantum mechanical approach to the dynamical many-body problem, the time-dependent density functional theory (TDDFT) might be inadequate to describe crucial observables that rely on two-body evolution behavior, like the…

Computational Physics · Physics 2025-11-17 Jiong-Hang Liang , Yunfeng Xiong

Particle-based stochastic reaction-diffusion (PBSRD) models are a popular approach for capturing stochasticity in reaction and transport processes across biological systems. In some contexts, the overdamped approximation inherent in such…

Biological Physics · Physics 2025-06-17 Samuel A. Isaacson , Qianhan Liu , Konstantinos Spiliopoulos , Chen Yao

Kinetic simulations have demonstrated that three-dimensional reconnection in collisionless regimes proceeds through the formation and interaction of magnetic flux ropes, which are generated due to the growth of tearing instabilities at…

Plasma Physics · Physics 2016-02-17 Cihan Akcay , William Daughton , Vyacheslav S. Lukin , Yi-Hsin Liu

This article proposes a hybrid adaptive numerical method based on the Dual Reciprocity Method (DRM) to solve problems with non-linear boundary conditions and large-scale problems, named Hybrid Adaptive Dual Reciprocity Method (H-DRM). The…

Numerical Analysis · Mathematics 2024-10-30 Rômulo Damasclin Chaves dos Santos , Jorge Henrique de Oliveira Sales

Two-tower models are widely adopted in the industrial-scale matching stage across a broad range of application domains, such as content recommendations, advertisement systems, and search engines. This model efficiently handles large-scale…

Information Retrieval · Computer Science 2025-03-03 Yihan Wang , Fei Xiong , Zhexin Han , Qi Song , Kaiqiao Zhan , Ben Wang

Discrete-state, continuous-time Markov models are becoming commonplace in the modelling of biochemical processes. The mathematical formulations that such models lead to are opaque, and, due to their complexity, are often considered…

Quantitative Methods · Quantitative Biology 2017-10-31 Christopher Lester

We propose a new geometric approach to describe the qualitative dynamics of chemical reactions networks. By this method we identify metastable regimes, defined as low dimensional regions of the phase space close to which the dynamics is…

Molecular Networks · Quantitative Biology 2015-11-19 Satya Swarup Samal , Aurélien Naldi , Dima Grigoriev , Andreas Weber , Nathalie Théret , Ovidiu Radulescu

We performed two-dimensional simulated tempering (ST) simulations of the two-dimensional Ising model with different lattice sizes in order to investigate the two-dimensional ST's applicability to dealing with phase transitions and to study…

Statistical Mechanics · Physics 2015-06-05 Tetsuro Nagai , Yuko Okamoto

Biochemical reactions typically occur at low copy numbers, but at once in crowded and diverse environments. Space and stochasticity therefore play an essential role in biochemical networks. Spatial-stochastic simulations have become a…

Thermal Radiative Transfer (TRT) is the dominant energy transfer mechanism in high-energy density physics with applications in inertial confinement fusion and astrophysics. The stiff interactions between the material and radiation fields…

Computational Physics · Physics 2019-05-01 Hans Hammer , HyeongKae Park , Luis Chacon

In this paper, using an algorithm based on the retrospective rejection sampling scheme, we propose an exact simulation of a Brownian diffusion whose drift admits several jumps. We treat explicitly and extensively the case of two jumps,…

Probability · Mathematics 2016-05-27 David Dereudre , Sara Mazzonetto , Sylvie Roelly

We describe a new algorithm for simulating complex Markoff-processes. We have used a reaction-cell method in order to simulate arbitrary reactions. It can be used for any kind of RDS on arbitrary topologies, including fractal dimensions or…

chem-ph · Physics 2009-10-28 Thomas Fricke , Dietmar Wendt

Tiny Recursive Models (TRMs) have recently demonstrated remarkable performance on ARC-AGI, showing that very small models can compete against large foundation models through a two-step refinement mechanism that updates an internal reasoning…

Machine Learning · Computer Science 2026-03-10 Paulius Rauba , Claudio Fanconi , Mihaela van der Schaar

We propose a two-scale neural network method for optimal control problems governed by convection-dominated convection-diffusion-reaction equations. Building on two-scale architectures developed for singularly perturbed forward problems, we…

Numerical Analysis · Mathematics 2026-05-19 Sijing Liu , Marcus Sarkis , Yi Zhang , Zhongqiang Zhang
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