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The stochastic simulation of biological systems is an increasingly popular technique in bioinformatics. It often is an enlightening technique, which may however result in being computational expensive. We discuss the main opportunities to…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-11-17 Marco Aldinucci , Mario Coppo , Ferruccio Damiani , Maurizio Drocco , Massimo Torquati , Angelo Troina

A system architecture is suggested for a System on Chip that will combine several different memristor-based, bio-inspired computation arrays with inter- and intra-chip communication. It will serve as a benchmark system for future…

Emerging Technologies · Computer Science 2025-05-19 Christian Grewing , Arun Ashok , Sabitha Kusuma , Michael Schiek , Andre Zambanini , Stefan van Waasen

MiMiC is a flexible and efficient framework for multiscale simulations in which different subsystems are treated by individual client programs. In this work, we present a new interface with OpenMM to be used as an MM client program and we…

Chemical Physics · Physics 2025-02-11 Andrea Levy , Andrej Antalík , Jógvan Magnus Haugaard Olsen , Ursula Rothlisberger

Rapid CMOS device size reduction resulted in billions of transistors on a chip have led to integration of many cores leading to many challenges such as increased power dissipation, thermal dissipation, occurrence of transient faults and…

Hardware Architecture · Computer Science 2023-04-12 Shashikiran Venkatesha , Ranjani Parthasarathi

MiMiC is a framework for performing multiscale simulations in which loosely coupled external programs describe individual subsystems at different resolutions and levels of theory. To make it highly efficient and flexible, we adopt an…

Recently the hardware emulation technique has emerged as a promising approach to accelerating hardware verification/debugging process. To fully evaluate the powerfulness of the emulation approach and demonstrate its potential impact, we…

Hardware Architecture · Computer Science 2016-02-10 Kai Cong , Li Lei , Zhenkun Yang , Fei Xie

Now days, manufacturers are focusing on increasing the concurrency in multiprocessor system-on-a-chip (MPSoC) architecture instead of increasing clock speed, for embedded systems. Traditionally lock-based synchronization is provided to…

Hardware Architecture · Computer Science 2012-02-06 Shaily Mittal , Nitin

Nowadays System-On-Chips (SoCs) have evolved considerably in term of performances, reliability and integration capacity. The last advantage has induced the growth of the number of cores or Intellectual Properties (IPs) in a same chip.…

Hardware Architecture · Computer Science 2013-12-13 Ahmed Ben Achballah , Slim Ben Saoud

Most atomic physics experiments are controlled by a digital pattern generator used to synchronize all equipment by providing triggers and clocks. Recently, the availability of well-documented open-source development tools has lifted the…

Instrumentation and Detectors · Physics 2021-06-16 A. Sitaram , G. K. Campbell , A. Restelli

The increasing density of transistors in Integrated Circuits (ICs) has enabled the development of highly integrated Systems-on-Chip (SoCs) and, more recently, Multiprocessor Systems-on-Chip (MPSoCs). To address scalability challenges in…

Hardware Architecture · Computer Science 2025-04-29 Rodrigo Cataldo , Cesar Marcon , Debora Matos

Growing power dissipation due to high performance requirement of processor suggests multicore processor technology, which has become the technology for present and next decade. Research advocates asymmetric multi-core processor system for…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-02-15 Alan David

Modern high-performance computing architectures (Multicore, GPU, Manycore) are based on tightly-coupled clusters of processing elements, physically implemented as rectangular tiles. Their size and aspect ratio strongly impact the achievable…

Hardware Architecture · Computer Science 2022-09-05 Gianna Paulin , Matheus Cavalcante , Paul Scheffler , Luca Bertaccini , Yichao Zhang , Frank Gürkaynak , Luca Benini

Microprocessors have revolutionized the world we live in and continuous efforts are being made to manufacture not only faster chips but also smarter ones. A number of techniques such as data level parallelism, instruction level parallelism…

Hardware Architecture · Computer Science 2011-10-18 Balaji Venu

Any architecture for practical quantum computing must be scalable. An attractive approach is to create multiple cores, computing regions of fixed size that are well-spaced but interlinked with communication channels. This exploded…

Quantum Physics · Physics 2022-11-08 Hamza Jnane , Brennan Undseth , Zhenyu Cai , Simon C Benjamin , Bálint Koczor

The smart integrated systems of tomorrow would demand a combination of micromechanical components and traditional electronics. On-chip solutions will be the ultimate goal. One way of making such systems is to implement the mechanical parts…

Other Computer Science · Computer Science 2008-02-22 O. Soeraasen , J. E. Ramstad

Scaling up hardware systems has become an important tactic for improving performance as Moore's law fades. Unfortunately, simulations of large hardware systems are often a design bottleneck due to slow throughput and long build times. In…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-07-31 Steven Herbst , Noah Moroze , Edgar Iglesias , Andreas Olofsson

There are increasing number of works addressing the design challenges of fast, scalable solutions for the growing number of new type of applications. Recently, many of the solutions aimed at improving processing element capabilities to…

Hardware Architecture · Computer Science 2019-12-16 Somnath Mazumdar , Alberto Scionti

Computers are a very important part of our lives and the major reason why they have been such a success is because of the excellent graphical operating systems that run on these powerful machines. As the computer hardware is becoming more…

Operating Systems · Computer Science 2012-05-30 Plawan Kumar Rath , G. N. Anil

Increasing complexity of modern multi-processor system on chip (MPSoC) and the decreasing feature size have introduced new challenges. System designers have to consider now aspects which were not part of the design process in past times.…

Other Computer Science · Computer Science 2014-05-14 Aurang Zaib , Prashanth Raju , Thomas Wild , Andreas Herkersdorf

The design space exploration of scaled-out manycores for communication-intensive applications (e.g., graph analytics and sparse linear algebra) is hampered due to either lack of scalability or accuracy of existing frameworks at simulating…

Hardware Architecture · Computer Science 2024-04-23 Marcelo Orenes-Vera , Esin Tureci , Margaret Martonosi , David Wentzlaff