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Tract-specific diffusion measures, as derived from brain diffusion MRI, have been linked to white matter tract structural integrity and neurodegeneration. As a consequence, there is a large interest in the automatic segmentation of white…

Image and Video Processing · Electrical Eng. & Systems 2019-08-28 Bo Li , Marius de Groot , Meike Vernooij , Arfan Ikram , Wiro Niessen , Esther Bron

Diffusion weighted imaging techniques permit us to infer microstructural detail in biological tissue in vivo and noninvasively. Modern sequences are based on advanced diffusion encoding schemes, allowing probing of more revealing measures…

Diffusion MRI tractography technique enables non-invasive visualization of the white matter pathways in the brain. It plays a crucial role in neuroscience and clinical fields by facilitating the study of brain connectivity and neurological…

Computer Vision and Pattern Recognition · Computer Science 2025-03-06 Yiqiong Yang , Yitian Yuan , Baoxing Ren , Ye Wu , Yanqiu Feng , Xinyuan Zhang

High angular resolution diffusion imaging data is the observed characteristic function for the local diffusion of water molecules in tissue. This data is used to infer structural information in brain imaging. Nonparametric scalar measures…

Applications · Statistics 2011-08-17 Sofia C. Olhede , Brandon Whitcher

Diffusion MRI tractography is an important tool for identifying and analyzing the intracranial course of cranial nerves (CNs). However, the complex environment of the skull base leads to ambiguous spatial correspondence between diffusion…

Image and Video Processing · Electrical Eng. & Systems 2024-09-23 Lei Xie , Qingrun Zeng , Huajun Zhou , Guoqiang Xie , Mingchu Li , Jiahao Huang , Jianan Cui , Hao Chen , Yuanjing Feng

In vivo mapping of the neurite density with diffusion MRI (dMRI) is a high but challenging aim. First, it is unknown whether all neurites exhibit completely anisotropic ('stick-like') diffusion. Second, the 'density' of tissue components…

Diffusion-weighted magnetic resonance imaging (dMRI) is widely used to assess the brain white matter. One of the most common computations in dMRI involves cross-subject tract-specific analysis, whereby dMRI-derived biomarkers are compared…

Image and Video Processing · Electrical Eng. & Systems 2023-07-12 Davood Karimi , Hamza Kebiri , Ali Gholipour

Diffusion magnetic resonance imaging (dMRI) provides critical insights into the microstructural and connectional organization of the human brain. However, the availability of high-field, open-access datasets that include raw k-space data…

Image and Video Processing · Electrical Eng. & Systems 2024-12-10 Shanshan Wang , Shoujun Yu , Jian Cheng , Sen Jia , Changjun Tie , Jiayu Zhu , Haohao Peng , Yijing Dong , Jianzhong He , Fan Zhang , Yaowen Xing , Xiuqin Jia , Qi Yang , Qiyuan Tian , Hua Guo , Guobin Li , Hairong Zheng

Diffusion-weighted imaging (DWI) is a powerful non-invasive tool which is widely used in clinical routine. Mostly, apparent diffusion coefficient maps are acquired, which cannot be directly related to cellular structure. More recently it…

In Diffusion Tensor Imaging (DTI) or High Angular Resolution Diffusion Imaging (HARDI), a tensor field or a spherical function field (e.g., an orientation distribution function field), can be estimated from measured diffusion weighted…

Computer Vision and Pattern Recognition · Computer Science 2017-10-17 Jian Cheng , Peter J. Basser

Fiber tracking based on diffusion weighted Magnetic Resonance Imaging (dMRI) allows for noninvasive reconstruction of fiber bundles in the human brain. In this chapter, we discuss sources of error and uncertainty in this technique, and…

Computer Vision and Pattern Recognition · Computer Science 2013-07-15 Thomas Schultz , Anna Vilanova , Ralph Brecheisen , Gordon Kindlmann

Diffusion tensor imaging provides important information on tissue structure and orientation of fiber tracts in brain white matter in vivo. It results in diffusion tensors, which are $3\times3$ symmetric positive definite (SPD) matrices,…

Applications · Statistics 2013-04-17 Ying Yuan , Hongtu Zhu , Martin Styner , John H. Gilmore , J. S. Marron

Brain network analysis plays a crucial role in diagnosing and monitoring neurodegenerative disorders such as Alzheimer's disease (AD). Existing approaches for constructing structural brain networks from diffusion tensor imaging (DTI) often…

Neurons and Cognition · Quantitative Biology 2025-05-30 Xuhang Chen , Michael Kwok-Po Ng , Kim-Fung Tsang , Chi-Man Pun , Shuqiang Wang

Geostatistical modeling for continuous point-referenced data has been extensively applied to neuroimaging because it produces efficient and valid statistical inference. However, diffusion tensor imaging (DTI), a neuroimaging characterizing…

Magnetic resonance imaging (MRI) is the method of choice for noninvasive studies of micrometer-scale structures in biological tissues via their effects on the time/frequency-dependent ("restricted") and anisotropic self-diffusion of water.…

Soft Condensed Matter · Physics 2021-11-16 Omar Narvaez , Maxime Yon , Hong Jiang , Diana Bernin , Eva Forssell-Aronsson , Alejandra Sierra , Daniel Topgaard

Portable, ultra-low-field (ULF) magnetic resonance imaging has the potential to expand access to neuroimaging but currently suffers from coarse spatial and angular resolutions and low signal-to-noise ratios. Diffusion tensor imaging (DTI),…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Mark D. Olchanyi , Annabel Sorby-Adams , John Kirsch , Brian L. Edlow , Ava Farnan , Renfei Liu , Matthew S. Rosen , Emery N. Brown , W. Taylor Kimberly , Juan Eugenio Iglesias

Deep learning has shown great potential in accelerating diffusion tensor imaging (DTI). Nevertheless, existing methods tend to suffer from Rician noise and detail loss in reconstructing the DTI-derived parametric maps especially when…

Computer Vision and Pattern Recognition · Computer Science 2024-01-04 Wenxin Fan , Jian Cheng , Cheng Li , Xinrui Ma , Jing Yang , Juan Zou , Ruoyou Wu , Qiegen Liu , Shanshan Wang

We present a method to estimate a multivariate Gaussian distribution of diffusion tensor features in a set of brain regions based on a small sample of healthy individuals, and use this distribution to identify imaging abnormalities in…

Applications · Statistics 2017-04-24 Matineh Shaker , Deniz Erdogmus , Jennifer Dy , Sylvain Bouix

The displacement distribution of a water molecular is characterized mathematically as Gaussianity without considering potential diffusion barriers and compartments. However, this is not true in real scenario: most biological tissues are…

Computation · Statistics 2015-07-27 Jia Liu

Models of diffusion MRI within a voxel are useful for making inferences about the properties of the tissue and inferring fiber orientation distribution used by tractography algorithms. A useful model must fit the data accurately. However,…

Quantitative Methods · Quantitative Biology 2017-02-08 Ariel Rokem , Jason D. Yeatman , Franco Pestilli , Kendrick N. Kay , Aviv Mezer , Stefan van der Walt , Brian A. Wandell