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Can LLM agents explore codebases and reason about code semantics without executing the code? We study this capability, which we call agentic code reasoning, and introduce semi-formal reasoning: a structured prompting methodology that…

Software Engineering · Computer Science 2026-03-05 Shubham Ugare , Satish Chandra

We explore the class of real numbers that are computed in real time by deterministic chemical reaction networks that are integral in the sense that all their reaction rate constants are positive integers. We say that such a reaction network…

Computational Complexity · Computer Science 2018-03-29 Xiang Huang , Titus H. Klinge , James I. Lathrop , Xiaoyuan Li , Jack H. Lutz

DNA-synthesis providers screen incoming orders by searching the requested sequence against curated hazard lists. We show that this baseline collapses to a 100% false-flag rate when the hazardous sequence comes from a taxonomic family absent…

Genomics · Quantitative Biology 2026-05-04 Najmul Hasan

Living systems operate out of equilibrium, continuously consuming energy to sustain organised, functional states. Their emergent behaviour usually relies on a set of interconnected chemical reaction networks (CRNs) driven by external fluxes…

Statistical Mechanics · Physics 2026-02-03 Shiling Liang , Paolo De Los Rios , Daniel Maria Busiello

Production deep learning systems across enterprise domains operate under constraints that academic benchmarks routinely obscure: labeled data is expensive, inference budgets are tight, and models that cannot explain their behavior are…

Machine Learning · Computer Science 2026-05-26 Rowan Martnishn

Convolutional neural networks (CNNs) are widely used for image recognition and text analysis, and have been suggested for application on one-dimensional data as a way to reduce the need for pre-processing steps. Pre-processing is an…

Machine Learning · Computer Science 2020-05-18 Ine L. Jernelv , Dag Roar Hjelme , Yuji Matsuura , Astrid Aksnes

We investigate the functioning of a classifying biological neural network from the perspective of statistical learning theory, modelled, in a simplified setting, as a continuous-time stochastic recurrent neural network (RNN) with identity…

Machine Learning · Statistics 2023-09-13 Wiebke Bartolomaeus , Youness Boutaib , Sandra Nestler , Holger Rauhut

This paper provides a collection of mathematical and computational tools for the study of robustness in nonlinear gene regulatory networks, represented by time- and state-discrete dynamical systems taking on multiple states. The focus is on…

Dynamical Systems · Mathematics 2016-08-30 Claus Kadelka , Yuan Li , Jack Kuipers , John O. Adeyeye , Reinhard Laubenbacher

This paper contributes to a development of randomized methods for neural networks. The proposed learner model is generated incrementally by stochastic configuration (SC) algorithms, termed as Stochastic Configuration Networks (SCNs). In…

Neural and Evolutionary Computing · Computer Science 2018-02-14 Dianhui Wang , Ming Li

The popularity of molecular computation has given rise to several models of abstraction, one of the more recent ones being Chemical Reaction Networks (CRNs). These are equivalent to other popular computational models, such as Vector…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-02-28 Robert M. Alaniz , Bin Fu , Timothy Gomez , Elise Grizzell , Andrew Rodriguez , Marco Rodriguez , Robert Schweller , Tim Wylie

We present a novel framework for chemical learning based on Competitive Dimerization Networks (CDNs) - systems in which multiple molecular species, e.g. proteins or DNA/RNA oligomers, reversibly bind to form dimers. We show that these…

Statistical Mechanics · Physics 2025-06-18 Alexei V. Tkachenko , Bortolo Matteo Mognetti , Sergei Maslov

Our work addresses the problem of predicting the highest priority functional group present in an organic molecule. Functional Groups are groups of bound atoms that determine the physical and chemical properties of organic molecules. In the…

Machine Learning · Computer Science 2026-03-26 Kunal Khatri , Vineet Mehta

We provide a rigorous definition of free-energy transduction and its efficiency in arbitrary -- linear or nonlinear -- open chemical reaction networks (CRNs) operating at steady state. Our method is based on the knowledge of the…

Molecular Networks · Quantitative Biology 2022-06-15 Artur Wachtel , Riccardo Rao , Massimiliano Esposito

Scale-free networks are abundant in nature and society, describing such diverse systems as the world wide web, the web of human sexual contacts, or the chemical network of a cell. All models used to generate a scale-free topology are…

Statistical Mechanics · Physics 2009-11-07 Albert-Laszlo Barabasi , Erzsebet Ravasz , Tamas Vicsek

Chemical reaction network theory is a powerful framework to describe and analyze chemical systems. While much about the concentration profile in an equilibrium state can be determined in terms of the graph structure, the overall reaction's…

Molecular Networks · Quantitative Biology 2024-02-29 Tomoharu Suda

We consider network design problems with deadline or delay. All previous results for these models are based on randomized embedding of the graph into a tree (HST) and then solving the problem on this tree. We show that this is not…

Data Structures and Algorithms · Computer Science 2020-04-20 Yossi Azar , Noam Touitou

Deep neural network (DNN) based approaches hold significant potential for reinforcement learning (RL) and have already shown remarkable gains over state-of-art methods in a number of applications. The effectiveness of DNN methods can be…

Machine Learning · Statistics 2017-06-01 Henghui Zhu , Feng Nan , Ioannis Paschalidis , Venkatesh Saligrama

In a reconfiguration version of an optimization problem $\mathcal{Q}$ the input is an instance of $\mathcal{Q}$ and two feasible solutions $S$ and $T$. The objective is to determine whether there exists a step-by-step transformation between…

Data Structures and Algorithms · Computer Science 2019-10-03 Daniel Lokshtanov , Amer E. Mouawad , Fahad Panolan , Sebastian Siebertz

The recent paper by W.-X. Wang, Y.-C. Lai, J. Ren, B. Li & C. Grebogi [arXiv:1107.2177v1] proposed a method for the control of complex networks with nonlinear dynamics based on linearizing the system around a finite number of local desired…

Disordered Systems and Neural Networks · Physics 2011-09-01 Jie Sun , Sean P. Cornelius , William L. Kath , Adilson E. Motter

The generalization properties of Gaussian processes depend heavily on the choice of kernel, and this choice remains a dark art. We present the Neural Kernel Network (NKN), a flexible family of kernels represented by a neural network. The…

Machine Learning · Computer Science 2018-08-07 Shengyang Sun , Guodong Zhang , Chaoqi Wang , Wenyuan Zeng , Jiaman Li , Roger Grosse
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