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Purpose: To estimate fiber-specific $T_1$ values, i.e. proxies for myelin content, in heterogeneous brain tissue. Methods: A diffusion-$T_1$ correlation experiment was carried out on an in vivo human brain using tensor-valued diffusion…

Medical Physics · Physics 2021-04-02 A. Reymbaut , J. Critchley , G. Durighel , T. Sprenger , M. Sughrue , K. Bryskhe , D. Topgaard

Diffusion MRI (dMRI) is the primary imaging modality used to study brain microstructure in vivo. Reliable and computationally efficient parameter inference for common dMRI biophysical models is a challenging inverse problem, due to factors…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 William Consagra , Lipeng Ning , Yogesh Rathi

Diffusion-weighted magnetic resonance imaging (D-MRI) is an in-vivo and non-invasive imaging technology to probe anatomical architectures of biological samples. The anatomy of white matter fiber tracts in the brain can be revealed to help…

Applications · Statistics 2023-05-18 Jilei Yang , Seungyong Hwang , Jie Peng

The purpose of this work is to develop a framework for single-subject analysis of diffusion tensor imaging (DTI) data. This framework (termed TOADDI) is capable of testing whether an individual tract as represented by the major eigenvector…

We propose a new model to describe diffusion processes within active deformable media. Our general theoretical framework is based on physical and mathematical considerations, and it suggests to use diffusion tensors directly coupled to…

Tissues and Organs · Quantitative Biology 2021-03-03 Christian Cherubini , Simonetta Filippi , Alessio Gizzi , Ricardo Ruiz-Baier

Diffusion MRI (dMRI) is a critical non-invasive technique to estimate fiber orientation distribution (FOD) for characterizing white matter integrity. Estimating FOD from single-shell low angular resolution dMRI (LAR-FOD) is limited by…

Computer Vision and Pattern Recognition · Computer Science 2025-12-19 Hao Tang , Hanyu Liu , Alessandro Perelli , Xi Chen , Chao Li

Tensor regression models, such as CP regression and Tucker regression, have many successful applications in neuroimaging analysis where the covariates are of ultrahigh dimensionality and possess complex spatial structures. The…

Machine Learning · Computer Science 2020-10-29 Da Xu

Tensor regression has attracted significant attention in statistical research. This study tackles the challenge of handling covariates with smooth varying structures. We introduce a novel framework, termed functional tensor regression,…

Methodology · Statistics 2025-06-12 Tongyu Li , Fang Yao , Anru R. Zhang

The first part of the paper is devoted to diffraction phenomena that can be expressed by fractional Fourier transforms whose orders are real numbers. According to a scalar theory, diffraction acts on the amplitude of the electric field as…

Optics · Physics 2022-03-17 Pierre Pellat-Finet , Éric Fogret

Brain network analysis plays a crucial role in diagnosing and monitoring neurodegenerative disorders such as Alzheimer's disease (AD). Existing approaches for constructing structural brain networks from diffusion tensor imaging (DTI) often…

Neurons and Cognition · Quantitative Biology 2025-05-30 Xuhang Chen , Michael Kwok-Po Ng , Kim-Fung Tsang , Chi-Man Pun , Shuqiang Wang

The connectivity and structural integrity of the white matter of the brain is nowadays known to be implicated into a wide range of brain-related disorders. However, it was not before the advent of diffusion Magnetic Resonance Imaging (dMRI)…

Computer Vision and Pattern Recognition · Computer Science 2014-01-27 Q. Zhou , O. Michailovich , Y. Rathi

Background: Diffusion tensor imaging (DTI) has been used to characterize forearm muscle architecture. Since only uniform sampling is performed for seed points rather than fiber tracts, the tracts may be unevenly distributed in the muscle…

Image and Video Processing · Electrical Eng. & Systems 2023-06-27 Yang Li , Shihan Ma , Jiamin Zhao , Qing Li , Xinjun Sheng

Diffusion models have shown incredible capabilities as generative models; indeed, they power the current state-of-the-art models on text-conditioned image generation such as Imagen and DALL-E 2. In this work we review, demystify, and unify…

Machine Learning · Computer Science 2022-08-26 Calvin Luo

In neuroscience, functional brain connectivity describes the connectivity between brain regions that share functional properties. Neuroscientists often characterize it by a time series of covariance matrices between functional measurements…

Methodology · Statistics 2019-07-09 Zhenhua Lin , Dehan Kong , Qiang Sun

Diffusion Tensor Imaging (DTI) provides the possibility of estimating the location and course of eloquent structures in the human brain. Knowledge about this is of high importance for preoperative planning of neurosurgical interventions and…

Computer Vision and Pattern Recognition · Computer Science 2011-03-11 Miriam H. A. Bauer , Jan Egger , Daniela Kuhnt , Sebastiano Barbieri , Jan Klein , Horst K. Hahn , Bernd Freisleben , Christopher Nimsky

We present a novel method for estimation of the fiber orientation distribution (FOD) function based on diffusion-weighted Magnetic Resonance Imaging (D-MRI) data. We formulate the problem of FOD estimation as a regression problem through…

Applications · Statistics 2016-12-23 Hao Yan , Owen Carmichael , Debashis Paul , Jie Peng

In this paper, we present a mathematical study of wave scattering by a hard elastic obstacle embedded in a soft elastic body in three dimensions. Our contributions are threefold. First, we characterize subwavelength resonances using the…

Analysis of PDEs · Mathematics 2025-01-14 Bochao Chen , Yixian Gao , Peijun Li , Yuanchun Ren

Diffusion models are generative models that have recently demonstrated impressive performances in terms of sampling quality and density estimation in high dimensions. They rely on a forward continuous diffusion process and a backward…

Machine Learning · Computer Science 2024-02-07 Christian Horvat , Jean-Pascal Pfister

The structure and variability of the brain's connections can be investigated via prediction of non-imaging phenotypes using neural networks. However, known neuroanatomical relationships between input features are generally ignored in…

Image and Video Processing · Electrical Eng. & Systems 2023-01-06 Yuqian Chen , Fan Zhang , Leo R. Zekelman , Tengfei Xue , Chaoyi Zhang , Yang Song , Nikos Makris , Yogesh Rathi , Weidong Cai , Lauren J. O'Donnell

Let $v$ be a vector field in a bounded open set $G\subset {\mathbb {R}}^d$. Suppose that $v$ is observed with a random noise at random points $X_i, i=1,...,n,$ that are independent and uniformly distributed in $G.$ The problem is to…

Statistics Theory · Mathematics 2009-09-29 Vladimir Koltchinskii , Lyudmila Sakhanenko , Songhe Cai