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Adherent biological cells generate traction forces on a substrate that play a central role for migration, mechanosensing, differentiation, and collective behavior. The established method for quantifying this cell-substrate interaction is…

Cell Behavior · Quantitative Biology 2020-05-05 Yunfei Huang , Gerhard Gompper , Benedikt Sabass

The future space-based gravitational wave observatory LISA will consist of a constellation of three spacecraft in a triangular constellation, connected by laser interferometers with 2.5 million-kilometer arms. Among other challenges, the…

General Relativity and Quantum Cosmology · Physics 2022-04-27 Quentin Baghi , James Ira Thorpe , Jacob Slutsky , John Baker

In this article we describe the first investigations of the complete engineering model of the Optical Metrology System (OMS), a key subsystem of the LISA Pathfinder science mission to space. The latter itself is a technological precursor…

Instrumentation and Detectors · Physics 2011-04-07 G. Hechenblaikner , R. Gerndt , U. Johann , P. Luetzow-Wentzky , V. Wand , H. Audley , K. Danzmann , A. Garcia-Marin , G. Heinzel , M. Nofrarias , F. Steier

The Laser Interferometer Space Antenna will be the first Gravitational Wave observatory in space. It is scheduled to fly in the early 2030's. LISA design predicts sensitivity levels that enable the detection a Stochastic Gravitational Wave…

Instrumentation and Methods for Astrophysics · Physics 2020-12-02 Nikolaos Karnesis , Marc Lilley , Antoine Petiteau

The Laser Interferometer Space Antenna (LISA) is due to launch in the mid-2030s. A key challenge for LISA data analysis is efficient Bayesian inference with parametrised gravitational-wave models, particularly for early inspirals of low-…

General Relativity and Quantum Cosmology · Physics 2025-12-15 Jethro Linley

Electrostatic force actuation is a key component of the system of geodesic reference test masses (TM) for the LISA orbiting gravitational wave observatory and in particular for performance at low frequencies, below 1 mHz, where the…

Modeling non-linear temporal trajectories is of fundamental interest in many application areas, such as in longitudinal microbiome analysis. Many existing methods focus on estimating mean trajectories, but it is also often of value to…

Methodology · Statistics 2020-12-02 Lingjing Jiang , Yuan Zhong , Chris Elrod , Loki Natarajan , Rob Knight , Wesley K. Thompson

The identification of Linear Time-Varying (LTV) systems from input-output data is a fundamental yet challenging ill-posed inverse problem. This work introduces a unified Bayesian framework that models the system's impulse response, $h(t,…

Machine Learning · Statistics 2026-04-01 Yaniv Shulman

This paper presents a new Bayesian model and algorithm used for depth and intensity profiling using full waveforms from the time-correlated single photon counting (TCSPC) measurement in the limit of very low photon counts. The model…

Applications · Statistics 2016-04-20 Yoann Altmann , Ximing Ren , Aongus McCarthy , Gerald S. Buller , Steve McLaughlin

Tracer-kinetic analysis of dynamic contrast-enhanced magnetic resonance imaging data is commonly performed with the well-known Tofts model and nonlinear least squares (NLLS) regression. This approach yields point estimates of model…

Medical Physics · Physics 2020-01-08 Andreas Mittermeier , Birgit Ertl-Wagner , Jens Ricke , Olaf Dietrich , Michael Ingrisch

We present an in-depth analysis of the LISA Pathfinder differential acceleration performance over the entire course of its science operations, spanning approximately 500 days. We find that: 1) the evolution of the Brownian noise that…

We present a Bayesian approach to identify optimal transformations that map model input points to low dimensional latent variables. The "projection" mapping consists of an orthonormal matrix that is considered a priori unknown and needs to…

Machine Learning · Statistics 2021-09-22 Panagiotis Tsilifis , Piyush Pandita , Sayan Ghosh , Valeria Andreoli , Thomas Vandeputte , Liping Wang

The proposed Laser Interferometer Space Antenna (LISA) mission is tasked with the detection and characterization of gravitational waves from various sources in the universe. This endeavor is challenged by transient displacement and…

Instrumentation and Methods for Astrophysics · Physics 2024-05-21 Niklas Houba , Luigi Ferraioli , Domenico Giardini

Tilt-to-length (TTL) noise induced by angular jitter of spacecraft and test masses can affect the sensitivity of space-based gravitational-wave detectors such as LISA, Taiji, and TianQin. Such angular jitter can be measured using the…

General Relativity and Quantum Cosmology · Physics 2026-02-09 Xue Wang , Gang Wang

Detecting stochastic gravitational wave backgrounds (SGWBs) with The Laser Interferometer Space Antenna (LISA) is among the mission science objectives. Disentangling SGWBs of astrophysical and cosmological origin is a challenging task,…

Cosmology and Nongalactic Astrophysics · Physics 2024-05-14 Federico Pozzoli , Riccardo Buscicchio , Christopher J. Moore , Francesco Haardt , Alberto Sesana

Earth observation from satellite sensory data poses challenging problems, where machine learning is currently a key player. In recent years, Gaussian Process (GP) regression has excelled in biophysical parameter estimation tasks from…

Instrumental artefacts, such as glitches, can significantly compromise the scientific output of LISA. Our methodology employs advanced Bayesian techniques, including Reversible Jump Markov Chain Monte Carlo and parallel tempering to find…

General Relativity and Quantum Cosmology · Physics 2025-09-16 Martina Muratore , Jonathan Gair , Olaf Hartwig , Michael L. Katz , Alexandre Toubiana

We investigate sources of error in acceleration statistics from Lagrangian Particle Tracking (LPT) data and demonstrate techniques to eliminate or minimise bias errors introduced during processing. Numerical simulations of particle tracking…

Fluid Dynamics · Physics 2018-11-14 John M. Lawson , Eberhard Bodenschatz , Cristian C. Lalescu , Michael Wilczek

Future space borne gravitational wave detectors will require a precise definition of calibration signals to ensure the achievement of their design sensitivity. The careful design of the test signals plays a key role in the correct…

Tilt-to-length coupling was the limiting noise source in LISA Pathfinder between 20 and 200 mHz before subtraction in post-processing. To prevent the adding of sensing noise to the data by the subtraction process, the success of this…

General Relativity and Quantum Cosmology · Physics 2023-08-07 Marie-Sophie Hartig , Gudrun Wanner