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Single Particle Tracking (SPT) can aid in understanding complex spatio-temporal processes. However, quantifying diffusivity and forces from individual live cell trajectories is complicated by inter- & intra-trajectory kinetic heterogeneity,…

Quantitative Methods · Quantitative Biology 2016-05-19 Christopher P. Calderon

Extracting information efficiently from quantum systems is a major component of quantum information processing tasks. Randomized measurements, or classical shadows, enable predicting many properties of arbitrary quantum states using few…

Single-shot error correction corrects data noise using only a single round of noisy measurements on the data qubits, removing the need for intensive measurement repetition. We introduce a general concept of confinement for quantum codes,…

Quantum Physics · Physics 2021-06-23 Armanda O. Quintavalle , Michael Vasmer , Joschka Roffe , Earl T. Campbell

Quantum metrology and sensing seek advantage in estimating an unknown parameter of some quantum state or channel, using entanglement such as spin squeezing produced by one-axis twists or other quantum resources. In particular, qubit phase…

Quantum Physics · Physics 2024-05-29 Tyler G. Thurtell , Akimasa Miyake

A central challenge in computational modeling of dynamic biological systems is parameter inference from experimental time course measurements. However, one would not only like to infer kinetic parameters but also study their variability…

Interferometers with single particles are susceptible for dephasing perturbations from the environment, such as electromagnetic oscillations or mechanical vibrations. On the one hand, this limits sensitive quantum phase measurements as it…

Diffusion models struggle to produce samples that respect constraints, a common requirement in scientific applications. Recent approaches have introduced regularization terms in the loss or guidance methods during sampling to enforce such…

Machine Learning · Computer Science 2026-02-06 Victor M. Yeom-Song , Severi Rissanen , Arno Solin , Samuel Kaski , Mingfei Sun

Quantum error correction is essential for reliable quantum computation, where surface codes demonstrate high fault-tolerant thresholds and hardware efficiency. However, noise in single-shot measurements limits logical readout fidelity,…

Quantum Physics · Physics 2025-05-13 Xiao-Yue Xu , Chen Ding , Wan-Su Bao

In diverse biological applications, particle tracking of passive microscopic species has become the experimental measurement of choice -- when either the materials are of limited volume, or so soft as to deform uncontrollably when…

Applications · Statistics 2019-11-18 Yun Ling , Martin Lysy , Ian Seim , Jay M. Newby , David B. Hill , Jeremy Cribb , M. Gregory Forest

Single-molecule localization microscopy allows practitioners to locate and track labeled molecules in biological systems. When extracting diffusion coefficients from the resulting trajectories, it is common practice to perform a linear fit…

Biological Physics · Physics 2024-06-19 Jakob Tómas Bullerjahn , Gerhard Hummer

Imaging data has become widely available to study biological systems at various scales, for example the motile behaviour of bacteria or the transport of mRNA, and it has the potential to transform our understanding of key transport…

Quantitative Methods · Quantitative Biology 2018-06-05 Jonathan U. Harrison , Ruth E. Baker

Quantum theory allows the traversing of multiple channels in a superposition of different orders. When the order in which the channels are traversed is controlled by an auxiliary quantum system, various unknown parameters of the channels…

Quantum Physics · Physics 2023-09-27 A. Z. Goldberg , L. L. Sanchez-Soto , K. Heshami

Quantum simulation, the study of strongly correlated quantum matter using synthetic quantum systems, has been the most successful application of quantum computers to date. It often requires determining observables with high precision, for…

Diffusion models have recently emerged as the dominant approach in visual generation tasks. However, the lengthy denoising chains and the computationally intensive noise estimation networks hinder their applicability in low-latency and…

Computer Vision and Pattern Recognition · Computer Science 2026-04-23 Qian Zeng , Jie Song , Yuanyu Wan , Huiqiong Wang , Mingli Song

Industrial, metrological, and medical applications provide a strong technological pull for advanced nanoscale sensors exploiting the unique sensitivity of quantum coherent systems to their environments. Essential to the functionality of…

Quantum Physics · Physics 2018-02-07 V. M. Frey , S. Mavadia , L. M. Norris , W. de Ferranti , D. Lucarelli , L. Viola , M. J. Biercuk

This paper proposes a belief propagation (BP)-based algorithm for sequential detection and estimation of multipath component (MPC) parameters based on radio signals. Under dynamic channel conditions with moving transmitter/receiver, the…

Information Theory · Computer Science 2022-05-24 Xuhong Li , Erik Leitinger , Alexander Venus , Fredrik Tufvesson

A distinguishing feature of active particles is the nature of the non-equilibrium noise driving their dynamics. Control of these noise properties is, therefore, of both fundamental and applied interest. We demonstrate emergent tuning of the…

Soft Condensed Matter · Physics 2021-01-05 Aniruddh Murali , Pritha Dolai , Ashwini Krishna , K. Vijay Kumar , Shashi Thutupalli

We describe how a single-particle tracking experiment should be designed in order for its recorded trajectories to contain the most information about a tracked particle's diffusion coefficient. The precision of estimators for the diffusion…

Biological Physics · Physics 2016-08-10 Christian L. Vestergaard

In an idealistic setting, quantum metrology protocols allow to sense physical parameters with mean squared error that scales as $1/N^2$ with the number of particles involved---substantially surpassing the $1/N$-scaling characteristic to…

Quantum Physics · Physics 2015-01-05 Jan Kolodynski

Restrictions to molecular motion by barriers (membranes) are ubiquitous in biological tissues, porous media and composite materials. A major challenge is to characterize the microstructure of a material or an organism nondestructively using…

Soft Condensed Matter · Physics 2011-03-11 Dmitry S. Novikov , Els Fieremans , Jens H. Jensen , Joseph A. Helpern
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