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We study the question of how best to assign an encouragement in a randomized encouragement study. In our setting, units arrive with covariates, receive a nudge toward treatment or control, acquire one of those statuses in a way that need…

Methodology · Statistics 2025-05-12 Tim Morrison , Minh Nguyen , Jonathan Chen , Michael Baiocchi , Art B. Owen

In optimal policy problems where treatment effects vary at the individual level, optimally allocating treatments to recipients is complex even when potential outcomes are known. We present an algorithm for multi-arm treatment allocation…

Econometrics · Economics 2024-04-30 Torben S. D. Johansen

Particle filtering is a powerful tool for target tracking. When the budget for observations is restricted, it is necessary to reduce the measurements to a limited amount of samples carefully selected. A discrete stochastic nonlinear…

Systems and Control · Electrical Eng. & Systems 2020-05-19 Antoine Aspeel , Amaury Gouverneur , Raphaël M. Jungers , Benoît Macq

Context: Utilization of operating theaters is a major cost driver in hospitals. Optimizing this variable through optimized surgery schedules may significantly lower cost and simultaneously improve medical outcomes. Previous studies proposed…

Applications · Statistics 2025-09-05 Harald Störrle , Anastasia Hort

Uncertainty in surgery durations continues to be difficult to account for in operating room scheduling. In particular, it remains complex to accurately incorporate uncertainty in surgical overtime constraints within mixed-integer linear…

Optimization and Control · Mathematics 2026-04-29 Cindy Pistorius , J. Theresia van Essen

Matching is a widely used causal inference design that aims to approximate a randomized experiment using observational data by forming matched sets of treated and control units based on similarities in their covariates. Ideally, treated…

Methodology · Statistics 2026-04-06 Jianan Zhu , Jeffrey Zhang , Zijian Guo , Siyu Heng

We describe an application of machine learning to the problem of predicting preterm birth. We conduct a secondary analysis on a clinical trial dataset collected by the National In- stitute of Child Health and Human Development (NICHD) while…

Online experiments in internet systems, also known as A/B tests, are used for a wide range of system tuning problems, such as optimizing recommender system ranking policies and learning adaptive streaming controllers. Decision-makers…

Machine Learning · Computer Science 2025-07-01 Qing Feng , Samuel Daulton , Benjamin Letham , Maximilian Balandat , Eytan Bakshy

Difference-in-differences (DID) is one of the most widely used causal inference frameworks in observational studies. However, most existing DID methods are designed for binary treatments and cannot be readily applied to non-binary treatment…

Methodology · Statistics 2025-12-01 Siyu Heng , Yuan Huang , Hyunseung Kang

Objective: Mixtures of temporally nonstationary signals are very common in biomedical applications. The nonstationarity of the source signals can be used as a discriminative property for signal separation. Herein, a semi-blind source…

Signal Processing · Electrical Eng. & Systems 2021-08-24 Fahimeh Jamshidian-Tehrani , Reza Sameni , Christian Jutten

Maternal mortality remains a significant global public health challenge. One promising approach to reducing maternal deaths occurring during facility-based childbirth is through early warning systems, which require the consistent monitoring…

In survival contexts, substantial literature exists on estimating optimal treatment regimes, where treatments are assigned based on personal characteristics to maximize the survival probability. These methods assume that a set of covariates…

Methodology · Statistics 2025-07-24 Junwen Xia , Zishu Zhan , Jingxiao Zhang

Parallel processing is a principle which enables simultaneous implementation of anesthesia induction and operating room (OR) turnover with the aim of improving OR utilization. In this article, we study the problem of scheduling surgeries…

Optimization and Control · Mathematics 2022-01-03 Batuhan Celik , Serhat Gul , Melih Celik

Motivated by an observational study of the effect of hospital ward versus intensive care unit admission on severe sepsis mortality, we develop methods to address two common problems in observational studies: (1) when there is a lack of…

Applications · Statistics 2015-08-13 Colin B. Fogarty , Mark E. Mikkelsen , David F. Gaieski , Dylan S. Small

Patients with motor control difficulties often "type" on a computer using a switch keyboard to guide a scanning cursor to text elements. We show how to optimize some parts of the design of switch keyboards by casting the design problem as…

Human-Computer Interaction · Computer Science 2015-03-18 Xiao Zhang , Kan Fang , Gregory Francis

Matching is an important tool in causal inference. The method provides a conceptually straightforward way to make groups of units comparable on observed characteristics. The use of the method is, however, limited to situations where the…

Methodology · Statistics 2019-06-18 Fredrik Sävje , Michael J. Higgins , Jasjeet S. Sekhon

Delayed outcomes are ubiquitous in online experimentation. When such a temporal dimension is present, treatment influences not only the outcome value but also the outcome timing, which can move in opposite directions. Motivated by the…

Methodology · Statistics 2026-03-30 Michael Lindon , Nathan Kallus

Problem definition: Access to accurate predictions of patients' outcomes can enhance medical staff's decision-making, which ultimately benefits all stakeholders in the hospitals. A large hospital network in the US has been collaborating…

This paper proposes a statistical framework of using artificial intelligence to improve human decision making. The performance of each human decision maker is benchmarked against that of machine predictions. We replace the diagnoses made by…

Econometrics · Economics 2024-12-10 Kai Feng , Han Hong , Ke Tang , Jingyuan Wang

Despite algorithms' potential to improve public services, adoption has been limited by concerns about effectiveness and equity. We conduct a randomized controlled trial ($N=4,681$) providing real-time algorithm support to Child Protective…

General Economics · Economics 2026-02-19 Marie-Pascale Grimon , Christopher Mills