English
Related papers

Related papers: Multiobjective optimization in Gene Expression Pro…

200 papers

Next-generation sequencing technologies now constitute a method of choice to measure gene expression. Data to analyze are read counts, commonly modeled using Negative Binomial distributions. A relevant issue associated with this…

Methodology · Statistics 2014-11-10 Elisabetta Bonafede , Franck Picard , Stéphane Robin , Cinzia Viroli

Multi-omic datasets offer opportunities for improved biomarker discovery in cancer research, but their high dimensionality and limited sample sizes make identifying compact and effective biomarker panels challenging. Feature selection in…

Genomics · Quantitative Biology 2026-04-02 Luca Cattelani , Vittorio Fortino

Multi-objective evolutionary algorithms (MOEAs) have become essential tools for solving multi-objective optimization problems (MOPs), making their running time analysis crucial for assessing algorithmic efficiency and guiding practical…

Neural and Evolutionary Computing · Computer Science 2025-07-04 Han Huang , Tianyu Wang , Chaoda Peng , Tongli He , Zhifeng Hao

Real-world optimization problems often involve stochastic and dynamic components. Evolutionary algorithms are particularly effective in these scenarios, as they can easily adapt to uncertain and changing environments but often uncertainty…

Neural and Evolutionary Computing · Computer Science 2024-04-10 Ishara Hewa Pathiranage , Frank Neumann , Denis Antipov , Aneta Neumann

Software quality estimation is a challenging and time-consuming activity, and models are crucial to face the complexity of such activity on modern software applications. In this context, software refactoring is a crucial activity within…

Software Engineering · Computer Science 2024-01-31 Vittorio Cortellessa , Daniele Di Pompeo , Vincenzo Stoico , Michele Tucci

Chance constrained optimization problems allow to model problems where constraints involving stochastic components should only be violated with a small probability. Evolutionary algorithms have been applied to this scenario and shown to…

Neural and Evolutionary Computing · Computer Science 2024-08-23 Frank Neumann , Carsten Witt

Efficiency of an optimization process is largely determined by the search algorithm and its fundamental characteristics. In a given optimization, a single type of algorithm is used in most applications. In this paper, we will investigate…

Optimization and Control · Mathematics 2012-03-30 Xin-She Yang , Suash Deb

Evolutionary Computation algorithms have been used to solve optimization problems in relation with architectural, hyper-parameter or training configuration, forging the field known today as Neural Architecture Search. These algorithms have…

Neural and Evolutionary Computing · Computer Science 2024-02-06 Javier Poyatos , Daniel Molina , Aitor Martínez , Javier Del Ser , Francisco Herrera

Many real-world applications require decision-makers to assess the quality of solutions while considering multiple conflicting objectives. Obtaining good approximation sets for highly constrained many-objective problems is often a difficult…

Artificial Intelligence · Computer Science 2025-08-13 Rodrigo Lankaites Pinheiro , Dario Landa-Silva , Wasakorn Laesanklang , Ademir Aparecido Constantino

Dynamic multiobjective optimization problems (DMOPs) feature time-varying objectives, which cause the Pareto optimal solution (POS) set to drift over time and make it difficult to maintain both convergence and diversity under limited…

Neural and Evolutionary Computing · Computer Science 2026-03-31 Jian Guan , Huolong Wu , Zhenzhong Wang , Gary G. Yen , Min Jiang

We propose the cone epsilon-dominance approach to improve convergence and diversity in multiobjective evolutionary algorithms (MOEAs). A cone-eps-MOEA is presented and compared with MOEAs based on the standard Pareto relation (NSGA-II,…

Neural and Evolutionary Computing · Computer Science 2020-08-11 Lucas S. Batista , Felipe Campelo , Frederico G. Guimarães , Jaime A. Ramírez

The research community continues to seek increasingly more advanced synthetic data generators to reliably evaluate the strengths and limitations of machine learning methods. This work aims to increase the availability of datasets…

Machine Learning · Computer Science 2026-01-30 Joanna Komorniczak

Molecular docking is an essential tool for drug design. It helps the scientist to rapidly know if two molecules, respectively called ligand and receptor, can be combined together to obtain a stable complex. We propose a new multi-objective…

Quantitative Methods · Quantitative Biology 2008-11-05 Jean-Charles Boisson , Laetitia Jourdan , El-Ghazali Talbi , Dragos Horvath

In multi-objective optimization problems, there might exist hidden objectives that are important to the decision-maker but are not being optimized. On the other hand, there might also exist irrelevant objectives that are being optimized but…

Optimization and Control · Mathematics 2022-06-06 Seyed Mahdi Shavarani , Manuel López-Ibáñez , Richard Allmendinger

Site-specific weather forecasts are essential to accurate prediction of power demand and are consequently of great interest to energy operators. However, weather forecasts from current numerical weather prediction (NWP) models lack the…

Atmospheric and Oceanic Physics · Physics 2024-08-02 MengMeng Han , Tennessee Leeuwenburg , Brad Murphy

Food production is a complex process which can benefit from many optimisation approaches. However, there is growing interest in methods that support customisation of food properties to satisfy individual consumer preferences. This paper…

Neural and Evolutionary Computing · Computer Science 2022-04-14 Mohammad Majid al-Rifaie , Marc Cavazza

This paper concerns the modeling and numerical simulation of the process of speciation. In particular, given conditions for which one or more speciation events within an ecosystem occur, our aim is to develop the necessary modeling and…

Populations and Evolution · Quantitative Biology 2021-10-08 Mats K. Brun , Elyes Ahmed , Jan Martin Nordbotten , Nils Christian Stenseth

The incentive for using Evolutionary Algorithms (EAs) for the automated optimization and training of deep neural networks (DNNs), a process referred to as neuroevolution, has gained momentum in recent years. The configuration and training…

Neural and Evolutionary Computing · Computer Science 2022-05-09 Fergal Stapleton , Edgar Galván , Ganesh Sistu , Senthil Yogamani

Data-driven evolutionary multi-objective optimization (EMO) has been recognized as an effective approach for multi-objective optimization problems with expensive objective functions. The current research is mainly developed for problems…

Neural and Evolutionary Computing · Computer Science 2022-05-31 Renzhi Chen , Ke Li

As evolutionary algorithms (EAs) are general-purpose optimization algorithms, recent theoretical studies have tried to analyze their performance for solving general problem classes, with the goal of providing a general theoretical…

Neural and Evolutionary Computing · Computer Science 2022-11-29 Chao Qian