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Probabilistic programs encode stochastic models as ordinary-looking programs with primitives for sampling numbers from predefined distributions and conditioning. Their applications include, among many others, machine learning and modeling…

Formal Languages and Automata Theory · Computer Science 2025-12-16 Dominik Geißler , Tobias Winkler

Inference of population structure from genetic data plays an important role in population and medical genetics studies. With the advancement and decreasing cost of sequencing technology, the increasingly available whole genome sequencing…

Applications · Statistics 2022-05-17 Yuyang Xu , Zhonghua Liu , Jianfeng Yao

Novel technologies in genomics allow creating data in exascale dimension with relatively minor effort of human and laboratory and thus monetary resources compared to capabilities only a decade ago. While the availability of this data…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-11-10 Sandra Gesing , Thomas Richard Connor , Ian Taylor

The Bayesian evidence, crucial ingredient for model selection, is arguably the most important quantity in Bayesian data analysis: at the same time, however, it is also one of the most difficult to compute. In this paper we present a…

Methodology · Statistics 2024-05-14 Stefano Rinaldi , Gabriele Demasi , Walter Del Pozzo , Otto A. Hannuksela

Monte Carlo inference has asymptotic guarantees, but can be slow when using generic proposals. Handcrafted proposals that rely on user knowledge about the posterior distribution can be efficient, but are difficult to derive and implement.…

Artificial Intelligence · Computer Science 2018-01-16 Marco F. Cusumano-Towner , Vikash K. Mansinghka

Motivation: Most existing methods for DNA sequence analysis rely on accurate sequences or genotypes. However, in applications of the next-generation sequencing (NGS), accurate genotypes may not be easily obtained (e.g. multi-sample…

Genomics · Quantitative Biology 2013-03-19 Heng Li

We are often interested in clustering objects that evolve over time and identifying solutions to the clustering problem for every time step. Evolutionary clustering provides insight into cluster evolution and temporal changes in cluster…

Machine Learning · Computer Science 2019-12-30 Natalia M. Arzeno , Haris Vikalo

Genetic data are frequently categorical and have complex dependence structures that are not always well understood. For this reason, clustering and classification based on genetic data, while highly relevant, are challenging statistical…

Methodology · Statistics 2016-06-13 Gabriela Bettella Cybis , Marcio Valk , Silvia Regina Costa Lopes

Phylogenetic placement refers to a family of tools and methods to analyze, visualize, and interpret the tsunami of metagenomic sequencing data generated by high-throughput sequencing. Compared to alternative (e. g., similarity-based)…

Populations and Evolution · Quantitative Biology 2025-01-09 Lucas Czech , Alexandros Stamatakis , Micah Dunthorn , Pierre Barbera

The package numericalsgps performs computations with and for numerical semigroups. Recently also affine semigroups are admitted as objects for calculations. This manuscript is a survey of what the package does, and at the same time of the…

Commutative Algebra · Mathematics 2019-02-12 Manuel Delgado , Pedro A. García Sánchez

Short tandem repeats (STRs) and single nucleotide polymorphisms (SNPs) are two kinds of commonly used markers in Y chromosome studies of forensic and population genetics. There has been increasing interest in the cost saving strategy by…

Populations and Evolution · Quantitative Biology 2013-10-22 Chuan-Chao Wang , Ling-Xiang Wang , Rukesh Shrestha , Shaoqing Wen , Manfei Zhang , Xinzhu Tong , Li Jin , Hui Li

Recently, it has become feasible to generate large-scale, multi-tissue gene expression data, where expression profiles are obtained from multiple tissues or organs sampled from dozens to hundreds of individuals. When traditional clustering…

Quantitative Methods · Quantitative Biology 2021-10-29 Pau Erola , Johan LM Björkegren , Tom Michoel

Matching one set of objects to another is a ubiquitous task in machine learning and computer vision that often reduces to some form of the quadratic assignment problem (QAP). The QAP is known to be notoriously hard, both in theory and in…

Machine Learning · Computer Science 2012-07-03 Deepti Pachauri , Maxwell Collins , Vikas SIngh , Risi Kondor

Statistical models serve as the cornerstone for hypothesis testing in empirical studies. This paper introduces a new cross-platform Python-based package designed to utilise different likelihood prescriptions via a flexible plug-in system.…

High Energy Physics - Phenomenology · Physics 2024-01-29 Jack Y. Araz

Jigsaw puzzle solving has been an increasingly popular task in the computer vision research community. Recent works have utilized cutting-edge architectures and computational approaches to reassemble groups of pieces into a coherent image,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-13 Ofir Itzhak Shahar , Gur Elkin , Ohad Ben-Shahar

IT systems of today are becoming larger and more complex, rendering their human supervision more difficult. Artificial Intelligence for IT Operations (AIOps) has been proposed to tackle modern IT administration challenges thanks to AI and…

Computers and Society · Computer Science 2020-12-17 Paolo Notaro , Jorge Cardoso , Michael Gerndt

The Python package pyABC provides a framework for approximate Bayesian computation (ABC), a likelihood-free parameter inference method popular in many research areas. At its core, it implements a sequential Monte-Carlo (SMC) scheme, with…

Quantitative Methods · Quantitative Biology 2022-03-25 Yannik Schälte , Emmanuel Klinger , Emad Alamoudi , Jan Hasenauer

Traditionally, signal classification is a process in which previous knowledge of the signals is needed. Human experts decide which features are extracted from the signals, and used as inputs to the classification system. This requirement…

Neural and Evolutionary Computing · Computer Science 2019-04-11 Daniel Rivero , Enrique Fernandez-Blanco , Julian Dorado , Alejandro Pazos

This paper proposes probabilistic conformal prediction (PCP), a predictive inference algorithm that estimates a target variable by a discontinuous predictive set. Given inputs, PCP construct the predictive set based on random samples from…

Machine Learning · Statistics 2022-06-22 Zhendong Wang , Ruijiang Gao , Mingzhang Yin , Mingyuan Zhou , David M. Blei

The de novo assembly of large, complex genomes is a significant challenge with currently available DNA sequencing technology. While many de novo assembly software packages are available, comparatively little attention has been paid to…

Genomics · Quantitative Biology 2013-07-31 Jared T. Simpson
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