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Three-dimensional microscopy is often limited by anisotropic spatial resolution, resulting in lower axial resolution than lateral resolution. Current State-of-The-Art (SoTA) isotropic reconstruction methods utilizing deep neural networks…

Image and Video Processing · Electrical Eng. & Systems 2023-06-22 Mingjie Pan , Yulu Gan , Fangxu Zhou , Jiaming Liu , Aimin Wang , Shanghang Zhang , Dawei Li

The thalamus is a subcortical gray matter structure that plays a key role in relaying sensory and motor signals within the brain. Its nuclei can atrophy or otherwise be affected by neurological disease and injuries including mild traumatic…

Image and Video Processing · Electrical Eng. & Systems 2023-02-02 Chang Yan , Muhan Shao , Zhangxing Bian , Anqi Feng , Yuan Xue , Jiachen Zhuo , Rao P. Gullapalli , Aaron Carass , Jerry L. Prince

Objective: Soft-tissue sarcoma spreads preferentially along muscle fibers. We explore the utility of deriving muscle fiber orientations from diffusion tensor MRI (DT-MRI) for defining the boundary of the clinical target volume in muscle…

Deep learning has shown great potential in accelerating diffusion tensor imaging (DTI). Nevertheless, existing methods tend to suffer from Rician noise and detail loss in reconstructing the DTI-derived parametric maps especially when…

Computer Vision and Pattern Recognition · Computer Science 2024-01-04 Wenxin Fan , Jian Cheng , Cheng Li , Xinrui Ma , Jing Yang , Juan Zou , Ruoyou Wu , Qiegen Liu , Shanshan Wang

Structural MRI(S-MRI) is one of the most versatile imaging modality that revolutionized the anatomical study of brain in past decades. The corpus callosum (CC) is the principal white matter fibre tract, enabling all kinds of…

Image and Video Processing · Electrical Eng. & Systems 2023-06-02 Vamshi Krishna Kancharla , Debanjali Bhattacharya , Neelam Sinha , Jitender Saini , Pramod Kumar Pal , Sandhya M

This paper is a contribution to the "BraTS 2023 Local Synthesis of Healthy Brain Tissue via Inpainting Challenge". The task of this challenge is to transform tumor tissue into healthy tissue in brain magnetic resonance (MR) images. This…

Image and Video Processing · Electrical Eng. & Systems 2024-10-24 Alicia Durrer , Philippe C. Cattin , Julia Wolleb

White matter (WM) tract segmentation is a crucial step for brain connectivity studies. It is performed on diffusion magnetic resonance imaging (dMRI), and deep neural networks (DNNs) have achieved promising segmentation accuracy. Existing…

Image and Video Processing · Electrical Eng. & Systems 2023-09-26 Wan Liu , Chuyang Ye

Clinical diffusion imaging requires short acquisition times and good image quality to permit its use in various medical applications. In turn, these demands require the development of a robust and efficient post-processing framework in…

Medical Physics · Physics 2015-02-18 Ivan I. Maximov , Farida Grinberg , Irene Neuner , N. Jon Shah

Diffusion MRI (dMRI) is a valuable imaging technique to study the brain in vivo. However, the resolution of dMRI is limited by the low signal-to-noise ratio (SNR) of this technique. Various acquisition strategies have been developed to…

Medical Physics · Physics 2023-05-30 Sajjad Feizollah , Christine L. Tardif

Tractography from high-dimensional diffusion magnetic resonance imaging (dMRI) data allows brain's structural connectivity analysis. Recent dMRI studies aim to compare connectivity patterns across subject groups and disease populations to…

Magnetic resonance (MR) images from multiple sources often show differences in image contrast related to acquisition settings or the used scanner type. For long-term studies, longitudinal comparability is essential but can be impaired by…

Image and Video Processing · Electrical Eng. & Systems 2023-03-16 Alicia Durrer , Julia Wolleb , Florentin Bieder , Tim Sinnecker , Matthias Weigel , Robin Sandkühler , Cristina Granziera , Özgür Yaldizli , Philippe C. Cattin

In silico tissue models enable evaluating quantitative models of magnetic resonance imaging. This includes validating and sensitivity analysis of imaging biomarkers and tissue microstructure parameters. We propose a novel method to generate…

Objective: To report imaging protocol and scheduling variance in routine care of glioblastoma patients in order to demonstrate challenges of integrating deep-learning models in glioblastoma care pathways. Additionally, to understand the…

Aim: This study aims to enhance interpretability and explainability of multi-modal prediction models integrating imaging and tabular patient data. Methods: We adapt the xAI methods Grad-CAM and Occlusion to multi-modal, partly interpretable…

Image and Video Processing · Electrical Eng. & Systems 2025-04-10 Jonas Brändli , Maurice Schneeberger , Lisa Herzog , Loran Avci , Nordin Dari , Martin Häansel , Hakim Baazaoui , Pascal Bühler , Susanne Wegener , Beate Sick

Diffusion models have shown impressive performance for image generation, often times outperforming other generative models. Since their introduction, researchers have extended the powerful noise-to-image denoising pipeline to discriminative…

Image and Video Processing · Electrical Eng. & Systems 2023-12-21 Fahim Ahmed Zaman , Mathews Jacob , Amanda Chang , Kan Liu , Milan Sonka , Xiaodong Wu

Subtle changes in white matter (WM) microstructure have been associated with normal aging and neurodegeneration. To study these associations in more detail, it is highly important that the WM tracts can be accurately and reproducibly…

Image and Video Processing · Electrical Eng. & Systems 2020-05-27 Bo Li , Marius de Groot , Rebecca M. E. Steketee , Rozanna Meijboom , Marion Smits , Meike W. Vernooij , M. Arfan Ikram , Jiren Liu , Wiro J. Niessen , Esther E. Bron

Information from an image occurs over multiple and distinct spatial scales. Image pyramid multiresolution representations are a useful data structure for image analysis and manipulation over a spectrum of spatial scales. This paper employs…

Computer Vision and Pattern Recognition · Computer Science 2022-04-22 Steve T. M. Ataky , Diego Saqui , Jonathan de Matos , Alceu S. Britto , Alessandro L. Koerich

Predicting brain maturity using noninvasive magnetic resonance images (MRI) can distinguish different age groups and help to assess neurodevelopmental disorders. However, group-wise differences are often less informative for assessing…

Neurons and Cognition · Quantitative Biology 2014-12-17 Cheol E. Han , Luis R. Peraza , John-Paul Taylor , Marcus Kaiser

White matter tractography is an advanced neuroimaging technique that reconstructs the 3D white matter pathways of the brain from diffusion MRI data. It can be framed as a pathfinding problem aiming to infer neural fiber trajectories from…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Itzik Waizman , Yakov Gusakov , Itay Benou , Tammy Riklin Raviv

Registration, which aims to find an optimal one-to-one correspondence between different data, is an important problem in various fields. This problem is especially challenging when large deformations occur. In this paper, we present a novel…

Differential Geometry · Mathematics 2013-10-08 Lam Ka Chun , Lok Ming Lui