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Chemical algorithms are statistical algorithms described and represented as chemical reaction networks. They are particularly attractive for traffic shaping and general control of network dynamics; they are analytically tractable, they…

Emerging Technologies · Computer Science 2016-01-21 Massimo Monti , Manolis Sifalakis , Christian F. Tschudin , Marco Luise

The study of the dynamics of chemical reactions, and in particular phenomena such as oscillating reactions, has led to the recognition that many dynamical properties of a chemical reaction can be predicted from graph theoretical properties…

Dynamical Systems · Mathematics 2022-11-08 J. J. P. Veerman , Tessa Whalen-Wagner , Ewan Kummel

A family of results, referred to as inheritance results, tell us which enlargements of a chemical reaction network (CRN) preserve its capacity for nontrivial behaviours such as multistationarity and oscillation. In this paper, the following…

Dynamical Systems · Mathematics 2023-02-23 Murad Banaji

In our earlier work, we introduced the concept of Gene Regulatory Neural Network (GRNN), which utilizes natural neural network-like structures inherent in biological cells to perform computing tasks using chemical inputs. We define this…

Neural and Evolutionary Computing · Computer Science 2024-03-14 Samitha Somathilaka , Adrian Ratwatte , Sasitharan Balasubramaniam , Mehmet Can Vuran , Witawas Srisa-an , Pietro Liò

The use of mathematical models has helped to shed light on countless phenomena in chemistry and biology. Often, though, one finds that systems of interest in these fields are dauntingly complex. In this paper, we attempt to synthesize and…

Molecular Networks · Quantitative Biology 2007-09-04 Mark Lipson

The population protocol model describes a network of $n$ anonymous agents who cannot control with whom they interact. The agents collectively solve some computational problem through random pairwise interactions, each agent updating its own…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-10-25 David Doty , Mahsa Eftekhari

Gene regulatory networks (GRNs) play a central role in cellular decision-making. Understanding their structure and how it impacts their dynamics constitutes thus a fundamental biological question. GRNs are frequently modeled as Boolean…

Molecular Networks · Quantitative Biology 2024-01-19 Claus Kadelka , Taras-Michael Butrie , Evan Hilton , Jack Kinseth , Addison Schmidt , Haris Serdarevic

A barrage relay network (BRN) is a broadcast oriented ad hoc network involving autonomous cooperative communication, a slotted time-division frame format, and a coarse slot-level synchronization. While inherently a broadcast protocol, BRNs…

Information Theory · Computer Science 2016-11-08 Salvatore Talarico , Matthew C. Valenti , Thomas R. Halford

We study genetic networks that produce many species of non-coding RNA molecules that are present at a moderate density, as typically exists in the cell. The associations of the many species of these RNA are modeled physically, taking into…

Genomics · Quantitative Biology 2014-09-08 J. M. Deutsch

Gene Regulatory Networks (GRNs) are intricate biological systems that control gene expression and regulation in response to environmental and developmental cues. Advances in computational biology, coupled with high throughput sequencing…

Machine Learning · Computer Science 2025-04-18 Akshata Hegde , Tom Nguyen , Jianlin Cheng

Modern computational chemistry has reached a stage at which massive exploration into chemical reaction space with unprecedented resolution with respect to the number of potentially relevant molecular structures has become possible. Various…

Chemical Physics · Physics 2020-04-27 Jan P. Unsleber , Markus Reiher

Graphs are central to the chemical sciences, providing a natural language to describe molecules, proteins, reactions, and industrial processes. They capture interactions and structures that underpin materials, biology, and medicine. This…

We study population protocols, a model of distributed computing appropriate for modeling well-mixed chemical reaction networks and other physical systems where agents exchange information in pairwise interactions, but have no control over…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-01-24 David Doty , Mahsa Eftekhari , Leszek Gąsieniec , Eric Severson , Grzegorz Stachowiak , Przemysław Uznański

Artificial neural network (ANN) has been widely used due to its strong nonlinear mapping ability, fault tolerance and self-learning ability. This article summarizes the development history of artificial neural networks, introduces three…

Systems and Control · Electrical Eng. & Systems 2021-10-12 Fei Liang , Taowen Zhang

We mathematically prove that chemical reaction networks without hidden layers can solve tasks for which spiking neural networks require hidden layers. Our proof uses the deterministic mass-action kinetics formulation of chemical reaction…

Machine Learning · Computer Science 2026-03-13 Sophie Jaffard , Ivo F. Sbalzarini

We consider here the morphogenesis (pattern formation) problem for some genetic network models. First, we show that any given spatio-temporal pattern can be generated by a genetic network involving a sufficiently large number of genes.…

Dynamical Systems · Mathematics 2007-05-23 S. Genieys , S. Vakulenko

Chemical kinetics and reaction engineering consists of the phenomenological framework for the disentanglement of reaction mechanisms, optimization of reaction performance and the rational design of chemical processes. Here, we utilize…

Machine Learning · Computer Science 2021-12-10 Gabriel S. Gusmão , Adhika P. Retnanto , Shashwati C. da Cunha , Andrew J. Medford

Informally, a chemical reaction network is "atomic" if each reaction may be interpreted as the rearrangement of indivisible units of matter. There are several reasonable definitions formalizing this idea. We investigate the computational…

Computational Complexity · Computer Science 2017-10-03 David Doty , Shaopeng Zhu

Graph transformation systems have the potential to be realistic models of chemistry, provided a comprehensive collection of reaction rules can be extracted from the body of chemical knowledge. A first key step for rule learning is the…

Discrete Mathematics · Computer Science 2016-04-22 Christoph Flamm , Daniel Merkle , Peter F. Stadler , Uffe Thorsen

This document is focused on computing systems implemented in technologies that communicate and compute with temporal transients. Although described in general terms, implementations of spiking neural networks are of primary interest. As…

Neural and Evolutionary Computing · Computer Science 2022-01-20 James E. Smith
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