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Denoising Diffusion Probabilistic Models (DDPM) are powerful state-of-the-art methods used to generate synthetic data from high-dimensional data distributions and are widely used for image, audio, and video generation as well as many more…

Machine Learning · Statistics 2025-04-25 Iskander Azangulov , George Deligiannidis , Judith Rousseau

Nonparametric two sample testing deals with the question of consistently deciding if two distributions are different, given samples from both, without making any parametric assumptions about the form of the distributions. The current…

Statistics Theory · Mathematics 2014-11-25 Aaditya Ramdas , Sashank J. Reddi , Barnabas Poczos , Aarti Singh , Larry Wasserman

Size distortion can occur if an asymptotic testing procedure requiring diverging sample sizes, is implemented to data with very small sample sizes. In this paper, we consider one-sample and two-sample tests for mean vectors when data are…

Methodology · Statistics 2022-03-17 Jun Li

We study high-dimensional two-sample mean comparison and address the curse of dimensionality through data-adaptive projections. Leveraging the low-dimensional and localized signal structures commonly seen in single-cell genomics data, our…

Methodology · Statistics 2025-06-12 Tianyu Zhang , Jing Lei , Kathryn Roeder

Asymptotic methods for hypothesis testing in high-dimensional data usually require the dimension of the observations to increase to infinity, often with an additional condition on its rate of increase compared to the sample size. On the…

Statistics Theory · Mathematics 2024-03-26 Joydeep Chowdhury , Subhajit Dutta , Marc G. Genton

The package High-dimensional Metrics (\Rpackage{hdm}) is an evolving collection of statistical methods for estimation and quantification of uncertainty in high-dimensional approximately sparse models. It focuses on providing confidence…

Machine Learning · Statistics 2017-09-28 Victor Chernozhukov , Chris Hansen , Martin Spindler

A common problem in genetics is that of testing whether a set of highly dependent gene expressions differ between two populations, typically in a high-dimensional setting where the data dimension is larger than the sample size. Most…

Methodology · Statistics 2015-03-11 Måns Thulin

Popular guidance for denoising diffusion probabilistic model (DDPM) linearly combines distinct conditional models together to provide enhanced control over samples. However, this approach overlooks nonlinear effects that become significant…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Candi Zheng , Yuan Lan

High-dimensional k-sample comparison is a common applied problem. We construct a class of easy-to-implement nonparametric distribution-free tests based on new tools and unexplored connections with spectral graph theory. The test is shown to…

Methodology · Statistics 2019-08-12 Subhadeep , Mukhopadhyay , Kaijun Wang

We consider the change point testing problem for high-dimensional time series. Unlike conventional approaches, where one tests whether the difference $\delta$ of the mean vectors before and after the change point is equal to zero, we argue…

Statistics Theory · Mathematics 2025-09-01 Pascal Quanz , Holger Dette

Consider $d$ dependent change point tests, each based on a CUSUM-statistic. We provide an asymptotic theory that allows us to deal with the maximum over all test statistics as both the sample size $n$ and $d$ tend to infinity. We achieve…

Statistics Theory · Mathematics 2017-12-07 Moritz Jirak

Repeated-measure designs allow comparisons within a group as well as between groups, and are commonly referred to as split-plot designs. While originating in agricultural experiments, they are now widely used in medical research,…

Computation · Statistics 2025-12-22 Paavo Sattler , Nils Hichert

Ensuring the robustness of deep learning models requires comprehensive and diverse testing. Existing approaches, often based on simple data augmentation techniques or generative adversarial networks, are limited in producing realistic and…

Computer Vision and Pattern Recognition · Computer Science 2025-02-10 Luciano Baresi , Davide Yi Xian Hu , Muhammad Irfan Mas'udi , Giovanni Quattrocchi

This paper presents a selective survey of recent developments in statistical inference and multiple testing for high-dimensional regression models, including linear and logistic regression. We examine the construction of confidence…

Methodology · Statistics 2023-01-26 T. Tony Cai , Zijian Guo , Yin Xia

The statistical analysis of discrete data has been the subject of extensive statistical research dating back to the work of Pearson. In this survey we review some recently developed methods for testing hypotheses about high-dimensional…

Machine Learning · Statistics 2017-12-19 Sivaraman Balakrishnan , Larry Wasserman

In typical high dimensional statistical inference problems, confidence intervals and hypothesis tests are performed for a low dimensional subset of model parameters under the assumption that the parameters of interest are unconstrained.…

Methodology · Statistics 2019-11-19 Ming Yu , Varun Gupta , Mladen Kolar

In this paper, we study inference for high-dimensional data characterized by small sample sizes relative to the dimension of the data. In particular, we provide an infinite-dimensional framework to study statistical models that involve…

Statistics Theory · Mathematics 2010-02-25 Jim Kuelbs , Anand N. Vidyashankar

We introduce sparse random projection, an important dimension-reduction tool from machine learning, for the estimation of discrete-choice models with high-dimensional choice sets. Initially, high-dimensional data are compressed into a…

Machine Learning · Statistics 2016-04-21 Khai X. Chiong , Matthew Shum

Next-generation sequencing technologies now constitute a method of choice to measure gene expression. Data to analyze are read counts, commonly modeled using Negative Binomial distributions. A relevant issue associated with this…

Methodology · Statistics 2014-11-10 Elisabetta Bonafede , Franck Picard , Stéphane Robin , Cinzia Viroli

This paper proposes a novel two-step strategy for testing the goodness-of-fit of parametric regression models in ultra-high dimensional sparse settings, where the predictor dimension far exceeds the sample size. This regime usually renders…

Methodology · Statistics 2025-12-30 Falong Tan , Jie Liu , Heng Peng , Lixing Zhu