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We present the results of an R&D study for a specialized processor capable of precisely reconstructing events with hundreds of charged-particle tracks in pixel and silicon strip detectors at $40\,\rm MHz$, thus suitable for processing LHC…

The advent of next-generation sequencing (NGS) has revolutionized genomic research by enabling cost-effective, high-throughput sequencing of a diverse range of organisms. This breakthrough has unleashed a "Cambrian explosion" in genomic…

Identifying gene splicing is a core and significant task confronted in modern collaboration between artificial intelligence and bioinformatics. Past decades have witnessed great efforts on this concern, such as the bio-plausible splicing…

Quantitative Methods · Quantitative Biology 2024-06-19 Qi-Jie Li , Qian Sun , Shao-Qun Zhang

This paper highlights first steps towards enabling graphics processing unit (GPU) acceleration of the task-parallel smoothed particle hydrodynamics (SPH) solver SWIFT. Novel combinations of algorithms are presented, enabling SWIFT to…

It is usually infeasible to fit and train an entire large deep neural network (DNN) model using a single edge device due to the limited resources. To facilitate intelligent applications across edge devices, researchers have proposed…

Machine Learning · Computer Science 2023-11-13 Yuhao Chen , Yuxuan Yan , Qianqian Yang , Yuanchao Shu , Shibo He , Zhiguo Shi , Jiming Chen

The algorithm-to-hardware High-level synthesis (HLS) tools today are purported to produce hardware comparable in quality to handcrafted designs, particularly with user directive driven or domains specific HLS. However, HLS tools are not…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-08-28 Vinay B. Y. Kumar , Pinalkumar Engineer , Mandar Datar , Yatish Turakhia , Saurabh Agarwal , Sanket Diwale , Sachin B. Patkar

Euler-Lagrange (EL) simulations provide a direct and robust framework for modeling disperse multiphase flows. However, they are computationally expensive. While various approaches have attempted to leverage heterogeneous computing…

Computational Engineering, Finance, and Science · Computer Science 2026-03-31 Silvio Schmalfuß , Sergey Lesnik , Henrik Rusche , Dennis Niedermeier

Multigrid algorithms are among the fastest iterative methods known today for solving large linear and some non-linear systems of equations. Greatly optimized for serial operation, they still have a great potential for parallelism not fully…

Numerical Analysis · Computer Science 2011-08-11 Julian Becerra-Sagredo , Carlos Malaga , Francisco Mandujano

This paper presents the use of element-based algebraic multigrid (AMGe) hierarchies, implemented in the ParELAG (Parallel Element Agglomeration Algebraic Multigrid Upscaling and Solvers) library, to produce multilevel preconditioners and…

Numerical Analysis · Mathematics 2023-07-04 Delyan Z. Kalchev , Panayot S. Vassilevski , Umberto Villa

Pairwise sequence alignment is one of the most computationally intensive kernels in genomic data analysis, accounting for more than 90% of the runtime for key bioinformatics applications. This method is particularly expensive for…

Hybrid parallelism techniques are essential for efficiently training large language models (LLMs). Nevertheless, current automatic parallel planning frameworks often overlook the simultaneous consideration of node heterogeneity and dynamic…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-06-04 Ruilong Wu , Xinjiao Li , Yisu Wang , Xinyu Chen , Dirk Kutscher

High-performance analysis of unstructured data like graphs now is critical for applications ranging from business intelligence to genome analysis. Towards this, data centers hold large graphs in memory to serve multiple concurrent queries…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-09-27 Emory Smith , Shannon Kuntz , Jason Riedy , Martin Deneroff

Recent efforts to improve the performance of neural network (NN) accelerators that meet today's application requirements have given rise to a new trend of logic-based NN inference relying on fixed-function combinational logic (FFCL). This…

Hardware Architecture · Computer Science 2023-04-14 Jingkai Hong , Arash Fayyazi , Amirhossein Esmaili , Mahdi Nazemi , Massoud Pedram

This work proposes RaNNC (Rapid Neural Network Connector) as middleware for automatic hybrid parallelism. In recent deep learning research, as exemplified by T5 and GPT-3, the size of neural network models continues to grow. Since such…

Machine Learning · Computer Science 2021-03-31 Masahiro Tanaka , Kenjiro Taura , Toshihiro Hanawa , Kentaro Torisawa

We present results of an R&D study for a specialized processor capable of precisely reconstructing, in pixel detectors, hundreds of charged-particle tracks from high-energy collisions at 40 MHz rate. We apply a highly parallel…

Convolutional Neural Networks (CNNs) and Transformers have achieved remarkable success in computer vision tasks. However, their deep architectures often lead to high computational redundancy, making them less suitable for…

Computer Vision and Pattern Recognition · Computer Science 2024-10-03 Novendra Setyawan , Ghufron Wahyu Kurniawan , Chi-Chia Sun , Jun-Wei Hsieh , Jing-Ming Guo , Wen-Kai Kuo

The field of connectomics faces unprecedented "big data" challenges. To reconstruct neuronal connectivity, automated pixel-level segmentation is required for petabytes of streaming electron microscopy data. Existing algorithms provide…

Spiking Neural Networks (SNNs) hold great potential to realize brain-inspired, energy-efficient computational systems. However, current SNNs still fall short in terms of multi-scale temporal processing compared to their biological…

Neural and Evolutionary Computing · Computer Science 2024-08-28 Xinyi Chen , Jibin Wu , Chenxiang Ma , Yinsong Yan , Yujie Wu , Kay Chen Tan

Recent years have witnessed the growing popularity of domain-specific accelerators (DSAs), such as Google's TPUs, for accelerating various applications such as deep learning, search, autonomous driving, etc. To facilitate DSA designs,…

Machine Learning · Computer Science 2023-06-06 Yunsheng Bai , Atefeh Sohrabizadeh , Zongyue Qin , Ziniu Hu , Yizhou Sun , Jason Cong

This paper explores the synergistic potential of neuromorphic and edge computing to create a versatile machine learning (ML) system tailored for processing data captured by dynamic vision sensors. We construct and train hybrid models,…

Neural and Evolutionary Computing · Computer Science 2024-07-12 James Seekings , Peyton Chandarana , Mahsa Ardakani , MohammadReza Mohammadi , Ramtin Zand