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Related papers: Concurrent and Accurate RNA Sequencing on Multicor…

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Pyrosequencing is among the emerging sequencing techniques, capable of generating upto 100,000 overlapping reads in a single run. This technique is much faster and cheaper than the existing state of the art sequencing technique such as…

Genomics · Quantitative Biology 2016-09-08 Fahad Saeed , Ashfaq Khokhar , Osvaldo Zagordi , Niko Beerenwinkel

Maximizing parallelism level in applications can be achieved by minimizing overheads due to load imbalances and waiting time due to memory latencies. Compiler optimization is one of the most effective solutions to tackle this problem. The…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-03-29 Zahra Khatami , Hartmut Kaiser , J. Ramanujam

Hardware accelerators, such as those based on GPUs and FPGAs, offer an excellent opportunity to efficiently parallelize functionalities. Recently, modern embedded platforms started being equipped with such accelerators, resulting in a…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-05-16 Daniel Casini , Paolo Pazzaglia , Alessandro Biondi , Marco Di Natale

Background: Short-read aligners have recently gained a lot of speed by exploiting the massive parallelism of GPU. An uprising alternative to GPU is Intel MIC; supercomputers like Tianhe-2, currently top of TOP500, is built with 48,000 MIC…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-02-21 Sze-Hang Chan , Jeanno Cheung , Edward Wu , Heng Wang , Chi-Man Liu , Xiaoqian Zhu , Shaoliang Peng , Ruibang Luo , Tak-Wah Lam

The High Luminosity upgrade of the Large Hadron Collider (HL-LHC) will produce particle collisions with up to 200 simultaneous proton-proton interactions. These unprecedented conditions will create a combinatorial complexity for…

Accelerating Human Action Recognition (HAR) efficiently for real-time surveillance and robotic systems on edge chips remains a challenging research field, given its high computational and memory requirements. This paper proposed an…

Computer Vision and Pattern Recognition · Computer Science 2023-11-08 Azzam Alhussain , Mingjie Lin

While there have been many studies on hardware acceleration for deep learning on images, there has been a rather limited focus on accelerating deep learning applications involving graphs. The unique characteristics of graphs, such as the…

Machine Learning · Computer Science 2021-11-12 Atefeh Sohrabizadeh , Yuze Chi , Jason Cong

Convolutional Neural Networks (CNNs) combine large amounts of parallelizable computation with frequent memory access. Field Programmable Gate Arrays (FPGAs) can achieve low latency and high throughput CNN inference by implementing dataflow…

Hardware Architecture · Computer Science 2024-08-20 Mario Doumet , Marius Stan , Mathew Hall , Vaughn Betz

Neutral atom quantum computers (NAQCs) are among the most promising computational platforms for quantum computing. Controlling and measuring individual atoms and their states, which often requires multiple imaging and image-analysis…

Quantum Physics · Physics 2026-04-02 Jonas Winklmann , Yian Yu , Xiaorang Guo , Korbinian Staudacher , Martin Schulz

In this paper, we describe a high-level synthesis (HLS) tool that automatically allows area/throughput trade-offs for implementing streaming task graphs (STG). Our tool targets a massively parallel processor array (MPPA) architecture, very…

Hardware Architecture · Computer Science 2016-06-14 Hossein Omidian , Guy G. F. Lemieux

We present PEANUT (ParallEl AligNment UTility), a highly parallel GPU-based read mapper with several distinguishing features, including a novel q-gram index (called the q-group index) with small memory footprint built on-the-fly over the…

Data Structures and Algorithms · Computer Science 2014-03-10 Johannes Köster , Sven Rahmann

In the era of diminishing returns from Moores Law, heterogeneous computing systems have emerged as a vital approach to enhance computational efficiency. This paper introduces a novel MLIR-based dialect, named hyper, designed to optimize…

Cryptography and Security · Computer Science 2025-06-05 Zhiyuan Tan , Liutong Han , Mingjie Xing , Yanjun Wu

We present both a novel Convolutional Neural Network (CNN) accelerator architecture and a network compiler for FPGAs that outperforms all prior work. Instead of having generic processing elements that together process one layer at a time,…

Hardware Architecture · Computer Science 2020-07-22 Mathew Hall , Vaughn Betz

The continually increasing volume of DNA sequence data has resulted in a growing demand for fast implementations of core algorithms. Computation of pairwise alignments between candidate haplotypes and sequencing reads using Pair-HMMs is a…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-01-27 Bertil Schmidt , Felix Kallenborn , Alexander Wichmann , Alejandro Chacon , Christian Hundt

This book focuses on the use of algorithmic high-level synthesis (HLS) to build application-specific FPGA systems. Our goal is to give the reader an appreciation of the process of creating an optimized hardware design using HLS. Although…

Hardware Architecture · Computer Science 2018-05-11 Ryan Kastner , Janarbek Matai , Stephen Neuendorffer

Nearest Neighbor Search (NNS) has recently drawn a rapid increase of interest due to its core role in managing high-dimensional vector data in data science and AI applications. The interest is fueled by the success of neural embedding,…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-02-01 Zhen Peng , Minjia Zhang , Kai Li , Ruoming Jin , Bin Ren

Heterogeneous MPSoCs comprise diverse processing units of varying compute capabilities. To date, the mapping strategies of neural networks (NNs) onto such systems are yet to exploit the full potential of processing parallelism, made…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-02-28 Halima Bouzidi , Mohanad Odema , Hamza Ouarnoughi , Smail Niar , Mohammad Abdullah Al Faruque

Metagenome assembly is the process of transforming a set of short, overlapping, and potentially erroneous DNA segments from environmental samples into the accurate representation of the underlying microbiomes's genomes. State-of-the-art…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-09-20 Evangelos Georganas , Rob Egan , Steven Hofmeyr , Eugene Goltsman , Bill Arndt , Andrew Tritt , Aydin Buluc , Leonid Oliker , Katherine Yelick

The high-throughput short-reads RNA-seq protocols often produce paired-end reads, with the middle portion of the fragments being unsequenced. We explore if the full-length fragments can be computationally reconstructed from the sequenced…

Genomics · Quantitative Biology 2023-10-06 Xiang Li , Mingfu Shao

At the last step of short read mapping, the candidate locations of the reads on the reference genome are verified to compute their differences from the corresponding reference segments using sequence alignment algorithms. Calculating the…

Genomics · Quantitative Biology 2024-07-04 Zülal Bingöl , Mohammed Alser , Onur Mutlu , Ozcan Ozturk , Can Alkan